Clinical Trials

157 enrolled 18 charts

Phase 2 Active not recruiting

Adenocarcinoma, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT03678883 2026-04-03

9-ING-41 in Patients With Advanced Cancers

350 enrolled

BreastCNSGastrointestinalGenitourinaryLymphoidOther hematologic neoplasmSarcomaThoracic

Bone Neoplasms, Breast Neoplasms, Glioma, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Non-Hodgkin, Neoplasm Metastasis, Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Pancreatic Neoplasms, Sarcoma, Colorectal Neoplasms, Leukemia-Lymphoma, Adult T-Cell

NCT06360354 2026-03-31

MTAPESTRY 103

Phase 1 Recruiting

350 enrolled

Neoplasms, Pancreatic Neoplasms

NCT05586516 2026-03-30

A Study to Assess an ATX Inhibitor (IOA-289) in Patients With Metastatic Pancreatic Cancer

16 enrolled

Fibrosis, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT02705196 2026-02-24

LOAd703 Oncolytic Virus Therapy for Pancreatic Cancer

51 enrolled

Adenoviridae Infections, Neoplasms, Pancreatic Neoplasms

NCT03929666 2025-09-12

A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer

74 enrolled

Biliary Tract Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT03697564 2025-08-06

Nivolumab + Cabiralizumab + Gemcitabine in Patients With Stage IV Pancreatic Cancer

2 enrolled 10 charts

Neoplasms, Pancreatic Neoplasms

NCT04306900 2025-07-29

TTX-030 in Combination With Immunotherapy and/or Chemotherapy in Subjects With Advanced Cancers

GastrointestinalGenitourinaryThoracic

185 enrolled 28 charts

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT03884556 2025-07-02

TTX-030 Single Agent and in Combination With Immunotherapy or Chemotherapy for Patients With Advanced Cancers

GastrointestinalGenitourinaryLymphoidThoracic

56 enrolled 19 charts

Urinary Bladder Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Pancreatic Neoplasms

NCT02632448 2025-05-02

A Study of LY2880070 in Participants With Advanced or Metastatic Cancer

BreastGastrointestinalGynecologicSarcoma

229 enrolled

Breast Neoplasms, Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Sarcoma, Colorectal Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors, Triple Negative Breast Neoplasms

NCT02650804 2025-03-26

BPM31510 Administered Intravenously With Gemcitabine in Advanced Pancreatic Cancer Patients

45 enrolled 14 charts

Neoplasms, Pancreatic Neoplasms

NCT05494866 2025-03-25

IntenSify

Phase 1 Terminated

6 enrolled

Adenocarcinoma, Carcinoma, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Glandular and Epithelial, Pancreatic Neoplasms

NCT03535727 2024-12-31

A Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic Cancer

48 enrolled 24 charts

Adenocarcinoma, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Neoplasms, Neoplasms, Glandular and Epithelial, Pancreatic Diseases, Pancreatic Neoplasms

NCT03997968 2024-12-24

A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors

BreastGastrointestinalGynecologicHead & NeckLymphoidPlasma cellSarcomaThoracic

169 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Head and Neck Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Lymphoma, Mantle-Cell, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT06119217 2024-12-04

Phase 2 Study of TTX-030 and Chemotherapy With or Without Budigalimab for 1L mPDAC Patients

Phase 2 Active not recruiting

194 enrolled

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT02009449 2024-11-15

IVY

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

353 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT03512756 2024-11-06

A Randomized Phase 2/3 Multi-Center Study of SM-88 in Participants With Metastatic Pancreatic Cancer

Phase 2/3 Terminated

130 enrolled 13 charts

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT03507491 2024-10-04

Nab-paclitaxel in Combination with Gemcitabine for Pediatric Relapsed and Refractory Solid Tumors

CNSGastrointestinalGenitourinarySarcoma

24 enrolled

Neoplasms, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma

NCT03267316 2024-08-22

CANFOUR

BreastGastrointestinalThoracic

167 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT01231347 2024-07-16

GAMMA

Phase 3 Completed

800 enrolled 11 charts

Endocrine Gland Neoplasms, Jaundice, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT02352337 2024-07-10

PANOPTIMOX

276 enrolled 12 charts

Neoplasms, Pancreatic Neoplasms

NCT04336098 2024-06-04

Study of SRF617 in Patients With Advanced Solid Tumors

85 enrolled

GastrointestinalThoracic

Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT02993731 2023-11-15

CanStem111P

Phase 3 Completed

1,134 enrolled 18 charts

Adenocarcinoma, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Pancreatic Diseases, Pancreatic Neoplasms, Carcinoma, Pancreatic Ductal

NCT04299880 2023-11-08

Rollover Study to Provide Continued Access to Napabucasin for Patients Enrolled in Boston Biomedical-sponsored Protocols

7 enrolled

Adenocarcinoma, Digestive System Diseases, Digestive System Neoplasms, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Pancreatic Neoplasms

NCT00020345 2023-10-31

Combination Chemotherapy and Radiation Therapy Plus Surgery in Treating Patients With Advanced Cancer of the Pancreas

Gastrointestinal Neoplasms, Neoplasms, Pancreatic Neoplasms

NCT01726582 2023-08-14

Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine")

229 enrolled 14 charts

Adenocarcinoma, Neoplasms, Pancreatic Neoplasms

NCT01964430 2023-06-28

apact

Phase 3 Completed

866 enrolled 21 charts

Adenocarcinoma, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Neoplasms, Neoplasms by Site, Pancreatic Diseases, Pancreatic Neoplasms

NCT04163900 2023-05-24

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Phase 3 Terminated

773 enrolled 15 charts

Adenocarcinoma, Biliary Tract Neoplasms, Digestive System Neoplasms, Neoplasm Metastasis, Neoplasms, Cholangiocarcinoma

NCT02210559 2023-03-02

A Study of Gemcitabine Plus Nab-paclitaxel With or Without FG-3019 in Participants With Locally Advanced, Unresectable Pancreatic Cancer

37 enrolled 16 charts

Neoplasms, Pancreatic Neoplasms

NCT03102320 2022-06-30

ARCS-Multi

BreastGastrointestinalThoracic

173 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasms, Pancreatic Neoplasms, Thymoma, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT02138383 2021-08-17

Enzalutamide in Combination With Gemcitabine and Nab-Paclitaxel for the Treatment of Advanced Pancreatic Cancer

25 enrolled

Neoplasms, Pancreatic Neoplasms

NCT02045602 2020-10-08

Phase I Dose Escalation Study of Intravenous VCN-01 With or Without Gemcitabine and Abraxane® in Patients With Advanced Solid Tumors

42 enrolled

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT01189929 2020-09-09

A Study of Gemcitabine and Demcizumab (OMP-21M18) With or Without Abraxane® as 1st-line Treatment in Subjects With Locally Advanced or Metastatic Pancreatic Cancer

57 enrolled

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT03027284 2020-05-19

A Study of Merestinib (LY2801653) in Japanese Participants With Advanced or Metastatic Cancer

19 enrolled

GastrointestinalLymphoid

Gallbladder Neoplasms, Lymphoma, Non-Hodgkin, Neoplasm Metastasis, Neoplasms, Cholangiocarcinoma

NCT03610100 2019-10-29

ACELARATE

Phase 2/3 Suspended

328 enrolled

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT03697239 2019-06-11

High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer

Phase 1/2 Withdrawn

Neoplasms, Pancreatic Neoplasms

NCT03797443 2019-05-31

High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer

Phase 1/2 Withdrawn

Neoplasms, Pancreatic Neoplasms

NCT03908333 2019-05-30

High Dose Ascorbic Acid and Nanoparticle Paclitaxel Protein Bound and Cisplatin and Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer

Phase 1/2 Withdrawn

Neoplasms, Pancreatic Neoplasms

NCT01088815 2019-04-26

Hedgehog Inhibitors for Metastatic Adenocarcinoma of the Pancreas

98 enrolled 14 charts

Adenocarcinoma, Carcinoma, Digestive System Diseases, Digestive System Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Pancreatic Diseases, Pancreatic Neoplasms

NCT01453153 2018-11-30

Study of Gemcitabine + PEGPH20 vs Gemcitabine Alone in Stage IV Previously Untreated Pancreatic Cancer

28 enrolled 31 charts

Neoplasms, Pancreatic Neoplasms

NCT01086332 2018-11-13

Evaluation of Nelfinavir and Chemoradiation for Pancreatic Cancer

Phase 1 Terminated

7 enrolled

Neoplasms, Pancreatic Neoplasms

NCT00557492 2018-09-25

Efficacy of Neoadjuvant Chemoradiation for Potentially Resectable Pancreas Cancer

59 enrolled 13 charts

Neoplasms, Pancreatic Neoplasms

NCT01663272 2018-09-19

A Trial of Cabozantinib (XL184) and Gemcitabine in Advanced Pancreatic Cancer

12 enrolled 6 charts

Neoplasms, Pancreatic Neoplasms

NCT00783172 2018-09-06

Opioid Growth Factor (OGF) and Gemcitabine: Novel Treatment for Pancreatic Cancer

Phase 1 Terminated

4 enrolled

Neoplasms, Pancreatic Neoplasms

NCT01373164 2018-05-16

A Study in Metastatic Cancer and Advanced or Metastatic Unresectable Pancreatic Cancer

170 enrolled 25 charts

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT01888978 2018-04-09

Molecularly Tailored Therapy for Pancreas Cancer

19 enrolled

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT00907166 2017-03-21

A Phase I/II Open-Label Dose-Escalation Clinical Trial of CPI-613 in Combination With Gemcitabine in Cancer Patients

Phase 1/2 Terminated

6 enrolled

Neoplasms, Pancreatic Neoplasms

NCT01964534 2017-01-31

AFUGEM

Phase 2 Unknown

114 enrolled

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT00336700 2016-09-19

A Phase II Study of Gemcitabine and Erlotinib As Adjuvant Therapy In Patients With Resected Pancreatic Cancer

Phase 2 Terminated

25 enrolled 10 charts