Clinical Trials Browser

OTHER × Neoplastic Syndromes, Hereditary × Gastrointestinal × Clear all

NCT07542405 2026-05-19

A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American Families

Phase NA Not yet recruiting

150 enrolled

Gastrointestinal

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary

NCT06708429 2026-04-24

LYNX-EYE

Recruiting

300 enrolled

GastrointestinalGynecologic

Turcot syndrome, Lynch syndrome I (site-specific colonic cancer), Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Colorectal Neoplasms, Endometrial Neoplasms, Lynch Syndrome II

NCT07461246 2026-03-10

RIPAF

Active not recruiting

1,500 enrolled

GastrointestinalSarcoma

Turcot syndrome, Attenuated familial adenomatous polyposis, Polyposis Syndrome, Hereditary Mixed, 1, Gardner Syndrome, Neoplastic Syndromes, Hereditary, Adenomatous Polyposis Coli, Colorectal Neoplasms, Desmoid Tumors

NCT07381985 2026-02-02

LINC

Phase NA Enrolling by invitation

200 enrolled

Gastrointestinal

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary

NCT04494945 2026-01-23

Identifying and Caring for Individuals With Inherited Cancer Syndrome

Phase NA Recruiting

27,500 enrolled

BreastGastrointestinalGynecologic

Carcinoma, Intraductal, Noninfiltrating, Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Hereditary Breast and Ovarian Cancer Syndrome

NCT04261972 2026-01-14

CHARM1

Active not recruiting

1,416 enrolled

BreastGastrointestinalGynecologic

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplasms, Neoplastic Syndromes, Hereditary, Hereditary Breast and Ovarian Cancer Syndrome

NCT06726642 2025-12-16

CHARM2

Recruiting

1,000 enrolled

BreastGastrointestinalGynecologic

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Stomach Neoplasms, Li-Fraumeni Syndrome, Hereditary Breast and Ovarian Cancer Syndrome

NCT06218433 2025-11-18

Urothelial Cancer Screening in Individuals With Lynch Syndrome Using a Urine Tumor DNA Panel (LS-URO Study)

Phase NA Recruiting

200 enrolled

GastrointestinalGenitourinary

Urogenital Diseases, Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary

NCT04763915 2025-09-19

IMPACT

Phase NA Active not recruiting

720 enrolled

BreastGastrointestinalGenitourinaryGynecologic

Breast Neoplasms, Neoplastic Syndromes, Hereditary, Prostatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT03426878 2025-09-11

CHARM

Phase NA Completed

967 enrolled 13 charts

BreastGastrointestinalGynecologic

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Hereditary Breast and Ovarian Cancer Syndrome

NCT06096688 2025-09-04

Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction

Recruiting

1,120 enrolled

GastrointestinalGynecologic

Carcinoma, Neoplastic Syndromes, Hereditary, Polyps, Colorectal Neoplasms, Endometrial Neoplasms

NCT06914726 2025-08-05

PC-CDS

Phase NA Enrolling by invitation

2,488 enrolled

BreastGastrointestinalGynecologic

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Ovarian Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT06999954 2025-05-31

SDS-GPS

Recruiting

8,000 enrolled

Classical hematologyGastrointestinalLymphoidMyeloid

Neutropenia, severe chronic, Neutropenia, Severe Congenital, Autosomal Recessive 3, Congenital Bone Marrow Failure Syndromes, Shwachman-Diamond Syndrome, Primary Immunodeficiency Diseases, Immunologic Deficiency Syndromes, Lymphoma, Follicular, Myelodysplastic Syndromes, Neoplastic Syndromes, Hereditary, Exocrine Pancreatic Insufficiency, Pancytopenia

NCT03979612 2019-06-07

GENEPY

Unknown

450 enrolled

BreastGastrointestinalGynecologic

Colorectal Neoplasms, Hereditary Nonpolyposis, Disease Susceptibility, Neoplasms, Neoplastic Syndromes, Hereditary, Hereditary Breast and Ovarian Cancer Syndrome

NCT00808743 2013-05-16

PreDuoFAP

Phase 2/3 Completed

37 enrolled

Gastrointestinal

Adenoma, Digestive System Diseases, Digestive System Neoplasms, Duodenal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplastic Syndromes, Hereditary, Adenomatous Polyposis Coli, Polyps, Adenomatous Polyps, Genetic Diseases, Inborn