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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 8Thoracic 1Lymphoid 1Gynecologic 1Genitourinary 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Colorectal Neoplasms 77Pancreatic Neoplasms 56Stomach Neoplasms 52Rectal Neoplasms 43Esophageal Squamous Cell Carcinoma 38Esophageal Neoplasms 38Neoplasm Metastasis 25Colonic Neoplasms 23Neoplasms 15Cholangiocarcinoma 13Liver Neoplasms 10Gastrointestinal Neoplasms 10Breast Neoplasms 9Adenocarcinoma Of Esophagus 9Carcinoma, Hepatocellular 7Anus Neoplasms 7Lung Neoplasms 6Head and Neck Neoplasms 6Biliary Tract Neoplasms 6Ovarian Neoplasms 5Melanoma 5Adenocarcinoma 5Kidney Neoplasms 4Gastrointestinal Diseases 4Digestive System Neoplasms 4Carcinoma, Squamous Cell 4Carcinoma, Non-Small-Cell Lung 4Uterine Cervical Neoplasms 3Sarcoma 3Lymphoma 3

Interventions

fludarabine 4aldesleukin 4Cyclophosphamide 4pembrolizumab 3fludarabine phosphate 2Taxes 2Radiotherapy 2Polymerase Chain Reaction 2Nicotine 2Gene Expression Profiling 2Fluorodeoxyglucose F18 2Counseling 2Cisplatin 2Bupropion 2Biopsy 2Adoptive Transfer 2motexafin gadolinium 1fluoromisonidazole 1entinostat 1durvalumab 1bintrafusp alfa protein, human 1Zinc Oxide 1Varenicline 1Tomography, X-Ray Computed 1Tobacco Use Cessation Devices 1Surgical Procedures, Operative 1Sucralfate 1Salts 1Rubidium-82 1Ritonavir 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Oropharyngeal Neoplasms × Drug Therapy × Gastrointestinal × Clear all
NCT03329950 2024-03-28

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

Celldex Therapeutics

Phase 1 Completed
132 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Mouth Neoplasms, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Cholangiocarcinoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Hyper-IgM Immunodeficiency Syndrome

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