Announcements Trials
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Phase

Phase 1 1

Status

Completed 24Unknown 5Terminated 3Recruiting 2Suspended 1Enrolling by invitation 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 11Lymphoid 11Myeloid 3Sarcoma 1Plasma cell 1Gastrointestinal 1

Conditions

Colorectal Neoplasms 29Pancreatic Neoplasms 18Stomach Neoplasms 13Carcinoma, Hepatocellular 13Breast Neoplasms 8Rectal Neoplasms 7Neoplasms 7Esophageal Neoplasms 7Colonic Neoplasms 7Carcinoma, Non-Small-Cell Lung 5Prostatic Neoplasms 4Lung Neoplasms 4Cholangiocarcinoma 4Carcinoma, Renal Cell 4Neoplasm Metastasis 3Endometrial Neoplasms 3Diabetes Mellitus 3Crohn Disease 3Uterine Cervical Neoplasms 2Triple Negative Breast Neoplasms 2Peritoneal Neoplasms 2Ovarian Neoplasms 2Multiple Sclerosis 2Multiple Myeloma 2Melanoma 2Liver Neoplasms 2Irritable Bowel Syndrome 2Head and Neck Neoplasms 2Gastrointestinal Stromal Tumors 2Gastrointestinal Neoplasms 2

Interventions

vactosertib 1fludarabine phosphate 1aldesleukin 1Interleukin-2 1IL32 protein, human 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Suspended × Precursor Cell Lymphoblastic Leukemia-Lymphoma × Gastrointestinal × Clear all
NCT05400122 2025-11-12

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

Case Comprehensive Cancer Center

Phase 1 Suspended
12 enrolled
GastrointestinalLymphoidMyeloidOther hematologic neoplasmPlasma cell

Esophageal Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasm Metastasis, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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