Clinical Trials

2,500 enrolled

Colonic Neoplasms, Rectal Neoplasms, Recurrence, Colorectal Neoplasms, Anastomotic Leak

NCT05283330 2026-03-20

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

BreastCNSGastrointestinalGenitourinaryGynecologicThoracic

48 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Colonic Neoplasms, Glioblastoma, Neoplasm Metastasis, Prostatic Neoplasms, Recurrence, Colorectal Neoplasms

NCT06158139 2026-03-19

Autologous CAR-T Cells Targeting B7-H3 in PDAC

27 enrolled

Pancreatic Neoplasms, Recurrence

NCT07221253 2026-03-17

AB02

Phase 3 Recruiting

1,100 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Recurrence

NCT04907643 2026-02-20

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

EndocrineGastrointestinalNET

360 enrolled

Cancer Pain, Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Biliary Tract Neoplasms, Carcinoid Tumor, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Stomach Neoplasms, Neuroendocrine Tumors, Visceral Pain

NCT06051695 2026-02-20

EVEREST-2

Phase 1/2 Recruiting

474 enrolled

GastrointestinalGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Colorectal Neoplasms

NCT04928677 2026-02-17

A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment

50 enrolled

Simpson-Golabi-Behmel syndrome, Recurrence, Hepatoblastoma

NCT06330064 2026-02-12

A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)

DermatologicGastrointestinalGenitourinaryGynecologicHead & Neck

520 enrolled

Adenocarcinoma Of Esophagus, Squamous Cell Carcinoma of Head and Neck, Biliary Tract Neoplasms, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Recurrence, Colorectal Neoplasms, Endometrial Neoplasms

NCT07198945 2026-02-04

STARLING

546 enrolled

Adenoma, Colonic Neoplasms, Colonic Polyps, Neoplasm Recurrence, Local, Recurrence

NCT04150042 2026-01-29

SHARON

BreastGastrointestinalGynecologicThoracic

24 enrolled

BreastGastrointestinal

Breast Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Recurrence

NCT05150691 2026-01-28

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

Phase 1/2 Recruiting

796 enrolled

Bile Duct Neoplasms, Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07337421 2026-01-13

Efcacy and Safety of Postoperative Adjuvant Hepatic Arterial Infusion Chemotherapy With mFOLFOX in Hepatocellular Carcinoma With High-risk Recurrence Factors

Carcinoma, Hepatocellular, Recurrence

NCT07337460 2026-01-13

Efficacy and Safety of Icaritin Combined With mFOLFOX in Postoperative HCC With High-risk Recurrence Factors

Carcinoma, Hepatocellular, Recurrence

NCT04400357 2025-12-18

PORTAL

Phase NA Completed

268 enrolled

Phase 2 Active not recruiting

Pancreatic Cyst, Pancreatic Neoplasms, Recurrence, Cholangiocarcinoma, Pancreatitis, Chronic

NCT02151084 2025-12-16

A Study of Different Dosing Schedules of Selumetinib With Cisplatin/Gemcitabine (CIS/GEM) Versus CIS/GEM Alone in Biliary Cancer

57 enrolled

Gallbladder Neoplasms, Recurrence

NCT04204850 2025-12-03

Cabozantinib to Treat Recurrent Liver Cancer Post Transplant

20 enrolled

Carcinoma, Hepatocellular, Recurrence

NCT04337177 2025-09-23

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

CNSGastrointestinalSarcoma

20 enrolled

Medulloblastoma, Neuroblastoma, Recurrence, Rhabdomyosarcoma, Sarcoma, Ewing, Hepatoblastoma

NCT05990543 2025-09-08

Combination of Nelmastobart and Capecitabine Therapy in Metastatic Colorectal Cancer

Phase 1/2 Active not recruiting

59 enrolled

Recurrence, Colorectal Neoplasms

NCT07098949 2025-08-01

Acupuncture Combined With Chemotherapy for Gastric Cancer After Surgery

346 enrolled

Recurrence, Stomach Neoplasms

NCT07077798 2025-07-22

Adjuvant Sintilimab Plus Lenvatinib for HCC Characterized With VETC Following Liver Resection

234 enrolled

Carcinoma, Hepatocellular, Recurrence

NCT01781728 2025-07-20

Palliative Stereotactic Radiation for Pancreatic or Periampullary Adenocarcinoma

Phase 2 Completed

48 enrolled 12 charts

DermatologicGastrointestinalThoracic

Pancreatic Neoplasms, Recurrence

NCT05573035 2025-07-01

A Study to Investigate LYL845 in Adults With Solid Tumors

Phase 1 Terminated

39 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Recurrence, Colorectal Neoplasms

NCT02804815 2025-06-10

Add-Aspirin: A Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival After Primary Therapy in Common Non Metastatic Solid Tumours

Phase 3 Active not recruiting

11,000 enrolled

BreastGastrointestinalGenitourinary

Breast Neoplasms, Neoplasms, Prostatic Neoplasms, Recurrence, Colorectal Neoplasms

NCT03959839 2025-06-03

DSETAMIS2018

Phase NA Completed

70 enrolled

Rectal Neoplasms, Recurrence

NCT01493206 2025-05-31

A Prospective Single Arm Study of Intraoperative Radiotherapy for Locally Advanced or Recurrent Rectal Cancer

Phase 2 Completed

32 enrolled

Rectal Neoplasms, Recurrence

NCT06090994 2025-05-07

Prevention of Recurrence and Metastasis of Colorectal Cancer by Comparing Huaier With Capecitabine Monotherapy

Phase 4 Recruiting

756 enrolled

BreastGastrointestinalGynecologicSarcoma

Neoplasm Metastasis, Recurrence, Colorectal Neoplasms

NCT02632448 2025-05-02

A Study of LY2880070 in Participants With Advanced or Metastatic Cancer

Phase 1/2 Completed

229 enrolled

Breast Neoplasms, Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Sarcoma, Colorectal Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors, Triple Negative Breast Neoplasms

NCT06420440 2025-05-01

Neoadjuvant Therapy in Patients With Resectable HCC Screened by a Multimodal Deep Learning Model

160 enrolled

Phase 1/2 Active not recruiting

Carcinoma, Hepatocellular, Recurrence

NCT05736731 2025-04-25

EVEREST-1

160 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms, Pancreatic Neoplasms, Recurrence, Colorectal Neoplasms

NCT05396300 2025-04-22

A Clinical Study of CEA-targeted CAR-T in the Treatment of CEA-positive Advanced Malignant Solid Tumors

43 enrolled

Esophageal Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Recurrence, Stomach Neoplasms, Colorectal Neoplasms

NCT06434896 2025-04-10

CrEATE

1,320 enrolled

Colonic Neoplasms, Recurrence

NCT06914674 2025-04-06

SPTP

Neoplasm Metastasis, Pancreatic Neoplasms, Recurrence

NCT00545545 2025-03-19

Safety/Efficacy Study of Imprime PGG With Cetuximab in Patients With Recurrent/Progressive Colorectal Carcinoma

Phase 1/2 Completed

32 enrolled 23 charts

Carcinoma, Recurrence, Colorectal Neoplasms

NCT05631574 2025-02-07

Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer

Phase 1 Terminated

13 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Recurrence, Colorectal Neoplasms

NCT06475352 2025-01-27

FUDOSE

400 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicMyeloidOther hematologic neoplasmSarcomaThoracic

Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Colorectal Neoplasms

NCT03154190 2025-01-24

Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer

Phase NA Completed

128 enrolled 24 charts

Urinary Bladder Neoplasms, Bone Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Esophageal Neoplasms, Melanoma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Sarcoma, Stomach Neoplasms, Leukemia, Myeloid, Acute, Disease Progression, Triple Negative Breast Neoplasms

NCT06791616 2025-01-24

Surveillance Intervals After Piecemeal Resection of Non-pedunculated Colorectal Lesions ≥20mm

746 enrolled

GastrointestinalGenitourinarySarcoma

Colonic Polyps, Recurrence, Colorectal Neoplasms

NCT04791228 2025-01-01

A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors

Phase 2 Withdrawn

Carcinoma, Carcinoma, Hepatocellular, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Recurrence, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing

NCT04908176 2024-12-13

A Drug-drug Interaction Study of Avapritinib and Midazolam

CNSGastrointestinalSarcoma

10 enrolled

Glioblastoma, Neoplasms, Recurrence, Gastrointestinal Stromal Tumors

NCT06609876 2024-12-03

Donafenib as Adjuvant Therapy Following Ablation for Recurrent HCC

108 enrolled

Carcinoma, Hepatocellular, Recurrence

NCT05476796 2024-10-24

LOGICAN

118 enrolled

BreastGastrointestinalGynecologicSarcomaThoracic

Adenocarcinoma Of Esophagus, Adenocarcinoma, Neoplasm Metastasis, Recurrence

NCT03345485 2024-10-21

EDO-S101

Phase 1/2 Completed

71 enrolled 39 charts

Breast Neoplasms, Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Recurrence, Sarcoma, Endometrial Neoplasms, Gastrointestinal Stromal Tumors, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT02595866 2024-08-09

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

DermatologicGastrointestinalLymphoidSarcomaThoracic

58 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Lung Neoplasms, Lymphoma, Non-Hodgkin, Melanoma, Neoplasm Metastasis, Neoplasms, Recurrence, Sarcoma, Kaposi, HIV Infections

NCT03439085 2024-07-09

DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers

Phase 2 Terminated

41 enrolled 13 charts

GastrointestinalGenitourinaryGynecologic

Anal Canal Carcinoma, Anus Neoplasms, Uterine Cervical Neoplasms, Neoplasm Metastasis, Neoplasms, Penile Neoplasms, Recurrence, Vaginal Neoplasms, Vulvar Neoplasms

NCT03464305 2024-03-19

ASPIRIN

Phase 3 Active not recruiting

148 enrolled

Phase 4 Not yet recruiting

Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Site, Pathologic Processes, Recurrence, Colorectal Neoplasms, Disease Attributes

NCT06311916 2024-03-15

Efficacy and Safety of Neoadjuvant Therapy in Patients With Resectable HCC Screened by a Multimodal Deep Learning Model.

312 enrolled

Carcinoma, Hepatocellular, Recurrence

NCT00020267 2024-03-04

Vaccine Therapy in Treating Patients With Metastatic Cancer

BreastDermatologicGastrointestinalSarcomaThoracic

Uveal Melanoma, Bone Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Eye Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Rectal Neoplasms, Recurrence, Sarcoma, Osteosarcoma, Skin Neoplasms, Colorectal Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Breast Neoplasms, Male, Muscle Neoplasms, Genetic Diseases, Inborn, Histiocytoma, Malignant Fibrous

NCT05861947 2024-01-31

JIVAN

Phase 1 Unknown

GastrointestinalGenitourinaryThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Colonic Neoplasms, Esophageal Neoplasms, Kidney Neoplasms, Recurrence, Stomach Neoplasms

NCT05910970 2024-01-23

PREVENT-2

Phase 3 Unknown

200 enrolled