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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other solid neoplasm 1Gynecologic 1Gastrointestinal 1

Conditions

Pancreatic Neoplasms 50Colorectal Neoplasms 39Stomach Neoplasms 27Carcinoma, Hepatocellular 26Ovarian Neoplasms 25Melanoma 21Breast Neoplasms 20Carcinoma, Non-Small-Cell Lung 19Neoplasms 15Neoplasm Metastasis 15Colonic Neoplasms 14Esophageal Neoplasms 13Uterine Cervical Neoplasms 11Sarcoma 10Liver Neoplasms 10Carcinoma, Renal Cell 10Lung Neoplasms 9Anus Neoplasms 9Rectal Neoplasms 8Head and Neck Neoplasms 8Squamous Cell Carcinoma of Head and Neck 7Osteosarcoma 7Triple Negative Breast Neoplasms 6Mesothelioma 6Hepatoblastoma 6Gastrointestinal Neoplasms 6Carcinoma 6Adenocarcinoma 6Vaginal Neoplasms 5Small Cell Lung Carcinoma 5

Interventions

pembrolizumab 2ribociclib 1fludarabine 1Quality of Life 1Plicamycin 1Patient Reported Outcome Measures 1Nivolumab 1Molecular Diagnostic Techniques 1Magnetic Resonance Spectroscopy 1Immunotherapy 1Fluorodeoxyglucose F18 1FAPI-46 1Drug Therapy 1Cyclophosphamide 1Blood Specimen Collection 1Biological Therapy 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Thymus Neoplasms × Cyclophosphamide × Gastrointestinal × Clear all
NCT06885697 2026-06-05

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

National Institutes of Health Clinical Center (CC)

Phase 1 Recruiting
100 enrolled
GastrointestinalGynecologicOther solid neoplasmThoracic

Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms

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