Announcements Trials
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Phase

Phase 2/3 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 2Endocrine 2Thoracic 1Plasma cell 1Other hematologic neoplasm 1Myeloid 1Gynecologic 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Colorectal Neoplasms 9Neoplasm Metastasis 4Sarcoma 3Pancreatic Neoplasms 3Lymphoma, Non-Hodgkin 3Glioma 3Breast Neoplasms 3Wilms Tumor 2Sarcoma, Ewing 2Rhabdomyosarcoma 2Rhabdoid Tumor 2Prostatic Neoplasms 2Ovarian Neoplasms 2Osteosarcoma 2Neuroectodermal Tumors, Primitive, Peripheral 2Neuroblastoma 2Neoplasms 2Multiple Myeloma 2Melanoma 2Histiocytosis, Langerhans-Cell 2Hepatoblastoma 2Hematologic Neoplasms 2Ependymoma 2Colorectal Cancer Metastatic 2Central Nervous System Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Xanthogranuloma, Juvenile 1Urinary Bladder Neoplasms 1Thyroid Carcinoma, Anaplastic 1Thyroid Cancer, Papillary 1

Interventions

trametinib 2dabrafenib 2Trastuzumab 2zimberelimab 1tumor necrosis factor-alpha, CNGRC fusion protein, human 1tislelizumab 1tipifarnib 1surufatinib 1sargramostim 1mercaptoundecahydrododecaborate 1cobimetinib 1aldesleukin 1Vemurafenib 1Tamoxifen 1Radiotherapy 1PLX8394 1Interleukin-12 Subunit p35 1Interleukin-12 1Doxorubicin 1Cisplatin 14-boronophenylalanine-fructose 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Thyroid Carcinoma, Anaplastic × Vemurafenib × Gastrointestinal × Clear all
NCT05768178 2025-11-24

DETERMINE

Cancer Research UK

Phase 2/3 Recruiting
30 enrolled
CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

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