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Phase

Phase 2/3 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 2Endocrine 2Thoracic 1Plasma cell 1Other hematologic neoplasm 1Myeloid 1Gynecologic 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Colorectal Neoplasms 8Pancreatic Neoplasms 5Carcinoma, Non-Small-Cell Lung 5Ovarian Neoplasms 4Neoplasms 4Melanoma 3Gastrointestinal Neoplasms 3Cholangiocarcinoma 3Breast Neoplasms 3Urinary Bladder Neoplasms 2Prostatic Neoplasms 2Neoplasms by Site 2Multiple Myeloma 2Hematologic Neoplasms 2Gallbladder Neoplasms 2Uterine Neoplasms 1Uterine Cervical Neoplasms 1Thyroid Neoplasms 1Thyroid Carcinoma, Anaplastic 1Thyroid Cancer, Papillary 1Thrombocytosis 1Thoracic Neoplasms 1Skin Neoplasms 1Sarcoma 1Respiratory Tract Neoplasms 1Respiratory Tract Diseases 1Primary Myelofibrosis 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pancreatic Adenocarcinoma 1Noonan Syndrome 1

Interventions

trametinib 2dabrafenib 2Trastuzumab 2zimberelimab 1tumor necrosis factor-alpha, CNGRC fusion protein, human 1tislelizumab 1tipifarnib 1surufatinib 1sargramostim 1mercaptoundecahydrododecaborate 1cobimetinib 1aldesleukin 1Vemurafenib 1Tamoxifen 1Radiotherapy 1PLX8394 1Interleukin-12 Subunit p35 1Interleukin-12 1Doxorubicin 1Cisplatin 14-boronophenylalanine-fructose 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Thyroid Carcinoma, Anaplastic × cobimetinib × Gastrointestinal × Clear all
NCT05768178 2025-11-24

DETERMINE

Cancer Research UK

Phase 2/3 Recruiting
30 enrolled
CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

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