Announcements Trials
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Phase

Phase 1 3Phase 3 2Phase 2 1Phase 1/2 1

Status

Completed 4Terminated 2Recruiting 1

Sponsor Class

INDUSTRY 7OTHER 3FED 1

Study Type

Interventional 7

Sponsor

Cancer Type

Gastrointestinal 7Other hematologic neoplasm 3Dermatologic 2CNS 2Thoracic 1Sarcoma 1Other solid neoplasm 1Lymphoid 1Gynecologic 1Genitourinary 1Breast 1

Conditions

Carcinoma, Hepatocellular 5Uveal Melanoma 1Stomach Neoplasms 1Neoplasms 1Liver Neoplasms 1Glioma 1Colorectal Neoplasms 1Carcinoma 1Advanced Pancreatic Cancer 1

Interventions

Gemcitabine 302Fluorouracil 296Oxaliplatin 269Bevacizumab 267Capecitabine 233Leucovorin 229pembrolizumab 215Irinotecan 185Cisplatin 142Cetuximab 142Nivolumab 131Paclitaxel 117130-nm albumin-bound paclitaxel 117Sorafenib 86Albumin-Bound Paclitaxel 75Docetaxel 65regorafenib 64atezolizumab 64IFL protocol 61Folfox protocol 61Trastuzumab 55Panitumumab 47durvalumab 46Ramucirumab 43Injections 43Sunitinib 41Drug Therapy 41Carboplatin 40trifluridine tipiracil drug combination 38lenvatinib 38

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
INDUSTRY × ADI PEG20 × Gastrointestinal × Clear all
NCT05317819 2025-12-18

Study of ADI-PEG 20 Versus Placebo in Subjects With High Arginine Level and Unresectable Hepatocellular Carcinoma

Polaris Group

Phase 3 Recruiting
300 enrolled
Gastrointestinal

Carcinoma, Hepatocellular

NCT02102022 2022-04-25

Ph 1-2 Study ADI-PEG 20 Plus FOLFOX in Subjects With Advanced GI Malignancies Focusing on Hepatocellular Carcinoma

Polaris Group

Phase 1/2 Terminated
140 enrolled
Gastrointestinal

Carcinoma, Hepatocellular, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT02101580 2020-10-01

Ph 1B Trial With ADI-PEG 20 Plus Nab-Paclitaxel and Gemcitabine in Subjects With Pancreatic Cancer

Polaris Group

Phase 1 Completed
21 enrolled
Gastrointestinal

Advanced Pancreatic Cancer

NCT02029690 2020-09-25

TRAP

Polaris Group

Phase 1 Terminated
85 enrolled
CNSDermatologicGastrointestinal

Uveal Melanoma, Carcinoma, Glioma, Carcinoma, Hepatocellular

NCT01287585 2019-09-06

ADI-PEG 20

Polaris Group

Phase 3 Completed
636 enrolled
Gastrointestinal

Carcinoma, Hepatocellular

NCT02006030 2018-09-04

TACE

Polaris Group

Phase 2 Completed
30 enrolled
Gastrointestinal

Liver Neoplasms

NCT02101593 2016-03-04

Ph 1 Trial of ADI PEG 20 Plus Sorafenib to Treat Patients With Liver Cancer

Polaris Group

Phase 1 Completed
8 enrolled
Gastrointestinal

Carcinoma, Hepatocellular

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