Announcements Trials
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Phase

Phase 1 3Phase 1/2 1

Status

Completed 14Terminated 4Withdrawn 1Unknown 1Not yet recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 1INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

Gastrointestinal 4Lymphoid 2Dermatologic 2Breast 2Sarcoma 1Other hematologic neoplasm 1Head & Neck 1Endocrine 1CNS 1

Conditions

Rectal Neoplasms 2Liver Neoplasms 1Carcinoma, Hepatocellular 1Biliary Tract Neoplasms 1

Interventions

Fluorouracil 145Gemcitabine 141Oxaliplatin 135Capecitabine 133Leucovorin 107Irinotecan 99Bevacizumab 92Cetuximab 69Cisplatin 67pembrolizumab 61Radiotherapy 60Nivolumab 41130-nm albumin-bound paclitaxel 41Sorafenib 39Docetaxel 34Albumin-Bound Paclitaxel 31Radiosurgery 28Paclitaxel 27Surgical Procedures, Operative 25regorafenib 24Erlotinib Hydrochloride 23Panitumumab 22Cyclophosphamide 21Celecoxib 20Trastuzumab 19Radiation 18Neoadjuvant Therapy 18IFL protocol 18atezolizumab 17Carboplatin 17

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Terminated × AZD 6244 × Gastrointestinal × Clear all
NCT01160926 2023-04-24

DREAMtherapy

The Christie NHS Foundation Trust

Phase 1 Terminated
31 enrolled
Gastrointestinal

Rectal Neoplasms

NCT01134601 2021-12-01

A Phase I Study of AZD6244 in Combination With Capecitabine and Radiotherapy in Locally Advanced Adenocarcinoma of the Rectum

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
1 enrolled 7 charts
Gastrointestinal

Rectal Neoplasms

NCT01949870 2016-05-13

Selumetinib (AZD6244, ARRY-142886) J-BTC Phase 1 Study

AstraZeneca

Phase 1 Terminated
6 enrolled 6 charts
Gastrointestinal

Biliary Tract Neoplasms

NCT01029418 2015-04-16

AZD6244 and Sorafenib in Advanced Hepatocellular Carcinoma

National Cancer Centre, Singapore

Phase 1/2 Terminated
30 enrolled
Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms

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