Clinical Trials Browser

Phase 1/2 × Capecitabine × Gastrointestinal × Clear all

NCT07040059 2026-04-17

A Phase 1b/2 Clinical Trial Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AUR103 Calcium in Patients With HER2-positive Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

Phase 1/2 Terminated

Gastrointestinal

HER 2 Positive Gastric Cancer

NCT06324357 2026-04-15

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Phase 1/2 Recruiting

BreastGastrointestinal

Adenocarcinoma Of Esophagus, Breast Neoplasms, Colorectal Neoplasms

NCT07529613 2026-04-14

T-DXd_HER2Low

Phase 1/2 Completed

Gastrointestinal

Stomach Neoplasms

NCT06469944 2026-04-13

MK-3475-06C

Phase 1/2 Recruiting

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Neoplasms

NCT05849480 2026-03-24

A Study of CDX-1140, a CD40 Agonist, in Combination With Capecitabine and Oxaliplatin (CAPOX) and Keytruda in Subjects With Biliary Tract Carcinoma (BTC)

Phase 1/2 Recruiting

Gastrointestinal

Bile Duct Neoplasms, Biliary Tract Neoplasms

NCT07456852 2026-03-09

Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine Therapy

Phase 1/2 Not yet recruiting

Gastrointestinal

Gastrointestinal Neoplasms

NCT07365592 2026-01-26

Neo-CD

Phase 1/2 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT07056777 2026-01-13

Evaluation of the Preliminary Efficacy and Safety of DR30206 in Combination With Standard Therapy in Patients With Gastrointestinal Cancer

Phase 1/2 Recruiting

Gastrointestinal

Gastrointestinal Neoplasms

NCT04564898 2026-01-08

TriComB

Phase 1/2 Active not recruiting

Gastrointestinal

Colorectal Cancer Metastatic

NCT05482893 2025-11-04

Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

Phase 1/2 Recruiting

Gastrointestinal

Biliary Tract Neoplasms

NCT05609370 2025-10-02

A Study Investigating the Efficacy and Safety of LBL-007 Plus Tislelizumab in Combination With Bevacizumab Plus Fluoropyrimidine Versus Bevacizumab Plus Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer

Phase 1/2 Active not recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05990543 2025-09-08

Combination of Nelmastobart and Capecitabine Therapy in Metastatic Colorectal Cancer

Phase 1/2 Active not recruiting

Gastrointestinal

Recurrence, Colorectal Neoplasms

NCT04031872 2025-09-05

LY3200882 and Capecitabine in Advanced Resistant TGF-beta Activated Colorectal Cancer (EORTC1615)

Phase 1/2 Withdrawn

Gastrointestinal

Colorectal Cancer Metastatic

NCT05775900 2025-09-03

Efficacy and Safety of Triweekly Cetuximab in Combination With Capecitabine as First-line Maintenance Treatment for KRAS/BRAF Wild-type Metastatic Colorectal Cancer

Phase 1/2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT04963088 2025-06-26

TALENT

Phase 1/2 Completed

Gastrointestinal

Stomach Neoplasms

NCT02795988 2025-04-16

A Study of IMU-131(HER-Vaxx) and Chemotherapy Compared to Chemotherapy Only in Patients With HER2 Positive Advanced Gastric Cancer

Phase 1/2 Completed

64 enrolled 20 charts

Gastrointestinal

Adenocarcinoma, Gastrointestinal Neoplasms, Neoplasm Metastasis

NCT06888674 2025-03-21

Personalized Tumor Neoantigen MRNA Therapy Adjuvant Treatment for Postoperative Pancreatic Cancer.

Phase 1/2 Not yet recruiting

Gastrointestinal

Pancreatic Cancer Resectable

NCT05093907 2025-03-10

A Study to Evaluate Safety and Efficacy of BEY1107 in Combination with Capecitabine in Patients with Metastatic Colorectal Cancer

Phase 1/2 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT03169777 2025-02-21

QUILT-3.050: NANT Colorectal Cancer (CRC) Vaccine: Combination Immunotherapy in Subjects With Recurrent or Metastatic CRC

Phase 1/2 Withdrawn

Gastrointestinal

Colorectal Neoplasms

NCT03535727 2024-12-31

A Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic Cancer

Phase 1/2 Completed

48 enrolled 24 charts

Gastrointestinal

Adenocarcinoma, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Neoplasms, Neoplasms, Glandular and Epithelial, Pancreatic Diseases, Pancreatic Neoplasms

NCT03997968 2024-12-24

A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors

Phase 1/2 Completed

BreastGastrointestinalGynecologicHead & NeckLymphoidPlasma cellSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Head and Neck Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma, Lymphoma, Mantle-Cell, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT02861300 2024-12-19

CB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal Cancer

Phase 1/2 Completed

50 enrolled 16 charts

Gastrointestinal

Colonic Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Rectal Neoplasms, Colorectal Neoplasms

NCT03329248 2024-12-12

QUILT-3.060: NANT Pancreatic Cancer Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

Phase 1/2 Terminated

6 enrolled 15 charts

Gastrointestinal

Pancreatic Neoplasms

NCT03563157 2024-12-11

QUILT 3.071: NANT Colorectal Cancer (CRC) Vaccine

Phase 1/2 Terminated

2 enrolled 13 charts

Gastrointestinal

Colorectal Neoplasms

NCT04276493 2024-12-06

Anti-HER2 Bispecific Antibody Zanidatamab (ZW25) Activity in Combination With Chemotherapy With/Without Tislelizumab

Phase 1/2 Completed

BreastGastrointestinal

Breast Neoplasms, Stomach Neoplasms

NCT04940546 2024-12-03

Neoadjuvant Safety of Sintilimab + XELOX + Bevacizumab in PMMR/MSS CRLM Patients

Phase 1/2 Active not recruiting

Gastrointestinal

Colorectal Cancer Metastatic

NCT03586869 2024-08-27

QUILT-3.080: NANT Pancreatic Cancer Vaccine

Phase 1/2 Terminated

3 enrolled 13 charts

Gastrointestinal

Pancreatic Neoplasms

NCT02024009 2024-07-25

SCALOP-2

Phase 1/2 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT05700656 2024-07-22

Galunisertib Combined With Capecitabine in Advanced CRC With PM

Phase 1/2 Recruiting

GastrointestinalGynecologic

Peritoneal Neoplasms, Colorectal Neoplasms

NCT03136406 2024-06-11

QUILT-3.039: NANT Pancreatic Cancer Vaccine: Combination Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

Phase 1/2 Terminated

3 enrolled 9 charts

Gastrointestinal

Pancreatic Neoplasms

NCT03387098 2024-05-22

QUILT-3.070:Pancreatic Cancer Vaccine: Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

Phase 1/2 Terminated

4 enrolled 9 charts

Gastrointestinal

Pancreatic Neoplasms

NCT02735239 2024-03-22

Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer

Phase 1/2 Completed

73 enrolled 18 charts

Gastrointestinal

Adenocarcinoma Of Esophagus, Diabetes Mellitus, Insulin-Dependent, 12, Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT03376659 2024-02-05

Durvalumab Plus CV301 With Maintenance Chemotherapy in Metastatic Colorectal or Pancreatic Adenocarcinoma

Phase 1/2 Terminated

8 enrolled 14 charts

Gastrointestinal

Pancreatic Neoplasms, Colorectal Neoplasms

NCT06195670 2024-01-08

Clinical Study of Short-course Radiotherapy Followed by Fruquintinib Plus Sintilimab vs Bevacizumab Plus Capecitabine as First Line Treatment in Advanced mCRC

Phase 1/2 Not yet recruiting

Gastrointestinal

Colorectal Neoplasms

NCT02024607 2023-11-15

A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Advanced Gastrointestinal Cancer

Phase 1/2 Completed

495 enrolled 18 charts

Gastrointestinal

Advanced Gastrointestinal Cancer

NCT04751955 2023-10-31

A Phase lb/ll, Open Label, Single Arm Study With Olinvacimab and Capecitabine in mCRC Patients (OLCAP)

Phase 1/2 Withdrawn

Gastrointestinal

Colorectal Cancer Metastatic

NCT02324543 2023-07-21

Study of Gemcitabine/Taxotere/Xeloda (GTX) in Combination With Cisplatin and Irinotecan in Subjects With Metastatic Pancreatic Cancer

Phase 1/2 Completed

47 enrolled 22 charts

Gastrointestinal

Metastatic Pancreatic Adenocarcinoma

NCT01898104 2023-03-24

V-shoRT-R3

Phase 1/2 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT03770689 2023-03-21

Study of Peposertib in Combination With Capecitabine and RT in Rectal Cancer

Phase 1/2 Completed

19 enrolled 21 charts

Gastrointestinal

Locally Advanced Rectal Cancer

NCT05608785 2022-11-08

Single-center, Multi-cohort Exploratory Phase Ib/II Clinical Study of First-line Treatment of Unresectable Locally Advanced/Advanced Adenocarcinoma of the Stomach or Gastroesophageal Junction Based on Different Genotypes

Phase 1/2 Unknown

Gastrointestinal

Stomach Neoplasms

NCT04782804 2022-08-18

Adjuvant PD-1 Antibody in Combination With Capecitabine for Patients With ICC at High-Risk of Postoperative Recurrence

Phase 1/2 Unknown

Gastrointestinal

Cholangiocarcinoma

NCT05016869 2022-08-18

Fruquintinib Plus Capecitabine as Maintenance Treatment of RAS / BRAF Wild-type Metastatic Colorectal Cancer

Phase 1/2 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT05091528 2022-08-18

A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers

Phase 1/2 Terminated

2 enrolled 9 charts

BreastGastrointestinalThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Stomach Neoplasms, Colorectal Neoplasms

NCT02465593 2022-01-11

A Study of PEP503(Radio-enhancer) With Radiotherapy and Chemotherapy for Patients With Rectal Cancer

Phase 1/2 Terminated

Gastrointestinal

Rectal Neoplasms

NCT00193128 2021-11-24

Preoperative Therapy With Oxaliplatin/Docetaxel/Capecitabine and Radiation in Resectable Esophagus Cancer

Phase 1/2 Completed

59 enrolled 8 charts

Gastrointestinal

Esophageal Neoplasms

NCT02948348 2021-09-16

Study to Nivolumab Following Preoperative Chemoradiotherapy

Phase 1/2 Unknown

Gastrointestinal

Rectal Neoplasms

NCT03564912 2021-08-25

Prospective Study on the Efficacy and Safety of 2 Week or 3 Week Xelox Regimen for Adjuvant Chemotherapy in CRC

Phase 1/2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT02393755 2021-07-08

Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer

Phase 1/2 Completed

42 enrolled 16 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT04943653 2021-07-06

IPXELOX

Phase 1/2 Unknown

Gastrointestinal

Stomach Neoplasms

NCT01077986 2021-04-21

Everolimus, Cetuximab and Capecitabine in Patients With Metastatic Pancreatic Cancer

Phase 1/2 Completed

Gastrointestinal

Pancreatic Neoplasms