Clinical Trials

542 enrolled

Colorectal Neoplasms

NCT05712356 2026-05-26

BOLSTER

Phase 2 Terminated

66 enrolled 12 charts

Bile Duct Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma, Disease Progression

NCT07284849 2026-05-26

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

700 enrolled

Phase 2 Active not recruiting

Colonic Neoplasms, Colorectal Neoplasms

NCT03548961 2026-05-22

Organ Preservation in Early Rectal Cancer Patients

19 enrolled

Rectal Neoplasms

NCT05099848 2026-05-22

A Trial of Conversion Treatment of HAIC Combined With Camrelizumab and Apatinib for Unresected Hepatocellular Carcinoma

21 enrolled

Phase 2 Not yet recruiting

Carcinoma, Hepatocellular

NCT07603375 2026-05-22

TNT Esophagus

60 enrolled

Phase 1 Not yet recruiting

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT07500298 2026-05-20

Phase 1 Study Of SAR445877 In Combination With FOLFOX6 And Bevacizumab As First-Line Treatment For Microsatellite Stable Metastatic Colorectal Cancer

41 enrolled

Colorectal Neoplasms

NCT06529718 2026-05-19

SEVILLA

72 enrolled

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT06598007 2026-05-19

A Study to Determine the Effect of CT3001 in Patients With Advanced Solid Tumors

Phase 1/2 Recruiting

78 enrolled

Phase 1/2 Active not recruiting

Colorectal Neoplasms

NCT04068610 2026-05-15

COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC

61 enrolled 35 charts

Colonic Neoplasms

NCT05702229 2026-05-14

Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

163 enrolled

Stomach Neoplasms

NCT06840886 2026-05-14

A Study of PHST001 in Advanced Solid Tumors

CNSGastrointestinalGynecologic

272 enrolled

Ovarian Neoplasms, Central Nervous System Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07221149 2026-05-14

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

Phase 2/3 Recruiting

690 enrolled

Adenocarcinoma Of Esophagus, Stomach Neoplasms

NCT07265674 2026-05-14

Beacon-BTC

480 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT00959647 2026-05-08

A Study of Vismodegib (GDC-0449) in Patients Treated With Vismodegib in a Previous Genentech-sponsored Phase I or II Cancer Study

DermatologicGastrointestinalGynecologic

19 enrolled 10 charts

Carcinoma, Basal Cell, Ovarian Neoplasms, Colorectal Neoplasms

NCT06663319 2026-05-08

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

220 enrolled

Gastrointestinal Neoplasms, Colorectal Neoplasms

NCT07466238 2026-05-08

HAIC Plus Systemic Therapy as De-escalation Therapy Strategy for Biliary Tract Cancer

Phase NA Recruiting

40 enrolled

Biliary Tract Neoplasms

NCT07221357 2026-05-06

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Phase 2/3 Recruiting

990 enrolled

Colorectal Neoplasms

NCT06179160 2026-05-04

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

710 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT07562490 2026-05-01

CLEAR-04

100 enrolled

Colorectal Neoplasms

NCT07562711 2026-05-01

CLEAR-02

340 enrolled

Colorectal Neoplasms

NCT06846346 2026-04-28

GRACIE

88 enrolled

Phase 2 Not yet recruiting

Adenocarcinoma Of Esophagus, Adenocarcinoma, Neoplasm Metastasis, Neoplasms

NCT07543783 2026-04-28

Efficacy and Safety of Low-dose Bevacizumab Plus Adebrelimab Combined With Transarterial Chemoembolization Followed by Hepatic Arterial Infusion Chemotherapy (TACE-HAIC) as First-line Treatment for Unresectable Hepatocellular Carcinoma: A Single-arm Phase 2 Trial

38 enrolled

Carcinoma, Hepatocellular

NCT06475352 2026-04-23

FUDOSE

400 enrolled

Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Colorectal Neoplasms

NCT06346197 2026-04-21

CIME

132 enrolled

Neoplasm Metastasis, Stomach Neoplasms

NCT06833866 2026-04-17

Phase I Trial of 5-Fluorouracil (5FU) -Based Therapy in Combination With Hydroxytyrosol (HT) in Patients With Advanced or Metastatic Colorectal Cancer

33 enrolled

Colorectal Neoplasms

NCT06625775 2026-04-13

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

BreastGastrointestinalThoracic

392 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT07522411 2026-04-13

Sequential FOLFOX-HAIC-TACE Plus Sintilimab-Bevacizumab Neoadjuvant Therapy Versus Direct Resection in Resectable High-Risk Recurrence Hepatocellular Carcinoma

Phase 1/2 Not yet recruiting

100 enrolled

Carcinoma, Hepatocellular

NCT03259035 2026-04-09

NEO: Neoadjuvant Chemotherapy, Excision and Observation for Early Rectal Cancer

58 enrolled 12 charts

Phase EARLY_PHASE1 Active not recruiting

Rectal Neoplasms

NCT05108428 2026-04-01

Adaptive Radiation for Locally Advanced Rectal Adenocarcinoma

20 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT06917079 2026-03-23

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

387 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Colorectal Neoplasms

NCT02359968 2026-03-18

PROTECT

106 enrolled

Esophageal Neoplasms

NCT04808323 2026-03-16

MRI-Guided Adaptive Radiation Therapy for Organ Preservation in Rectal Cancer

22 enrolled

Rectal Neoplasms

NCT05733689 2026-03-10

Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial)

20 enrolled

Gastroesophageal Adenocarcinoma

NCT04215731 2026-03-03

FOBEAR

582 enrolled

Phase EARLY_PHASE1 Recruiting

Rectal Neoplasms

NCT07193862 2026-02-27

Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis

10 enrolled

Phase EARLY_PHASE1 Not yet recruiting

Colorectal Cancer Metastatic

NCT07318389 2026-02-27

ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic Colorectal Cancer

100 enrolled

Colorectal Neoplasms

NCT07323576 2026-02-09

INAVO-CRC

Phase 2 Withdrawn

Colorectal Neoplasms

NCT00208260 2026-02-05

Intensified Chemotherapy in CRC After Resection of Liver Metastases

Phase 2/3 Completed

124 enrolled

Colorectal Neoplasms

NCT07389265 2026-02-05

CAPRI-3 GOIM

480 enrolled

Colorectal Neoplasms

NCT03092895 2026-01-29

A Study of SHR-1210 in Combination With Apatinib or Chemotherapy in Subjects With Advanced PLC or BTC

157 enrolled 17 charts

Advanced Primary Liver Cancer

NCT05855200 2026-01-23

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

892 enrolled

Phase 2 Not yet recruiting

Colonic Neoplasms

NCT07353827 2026-01-20

FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma

36 enrolled

Phase 3 Not yet recruiting

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma

NCT07340567 2026-01-14

CIRCULATEIII

2,450 enrolled

Phase 2 Active not recruiting

Colorectal Neoplasms

NCT06106308 2026-01-12

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation

113 enrolled

Phase 1 Active not recruiting

Colorectal Neoplasms

NCT06838338 2026-01-08

JAB-21822 Combined With Chemotherapy and Bevacizumab in Second-line KRAS G12C CRC

30 enrolled

Colorectal Neoplasms

NCT07309289 2025-12-30

NALIRIFOX Plus Targeted Therapy Versus FOLFOX Plus Targeted Therapy as First-line Treatment for Metastatic Colorectal Cancer

144 enrolled

Colorectal Neoplasms

NCT05171166 2025-12-18

Neoadjuvant HAIC of TACE Plus Donafenib in BCLC B Stage HCC: a Multi-center Randomized Controlled Trial.

Phase 2/3 Terminated

18 enrolled

Carcinoma, Hepatocellular

NCT06154538 2025-11-28

Immune Checkpoint Inhibitors + Chemotherapy Versus Chemotherapy in the Neoadjuvant Treatment of Locally Advanced Colorectal Cancer

170 enrolled

Phase 3 Not yet recruiting

Locally Advanced Colorectal Carcinoma

NCT06783491 2025-11-24

FOXHIPECT4

1,083 enrolled