Clinical Trials

39 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01658878 2025-12-24

CheckMate040

657 enrolled 57 charts 5 FDA

DermatologicGastrointestinalGenitourinaryGynecologicHead & Neck

Carcinoma, Hepatocellular

NCT04157985 2025-12-11

Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors

Phase 3 Completed

161 enrolled

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Melanoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Cholangiocarcinoma

NCT03377361 2025-12-03

CheckMate 9N9

325 enrolled 31 charts

Colorectal Neoplasms

NCT02060188 2025-11-06

CheckMate142

385 enrolled 17 charts 4 FDA

GastrointestinalOther solid neoplasm

Microsatellite Unstable Colorectal Cancer

NCT03404960 2025-10-10

Parpvax

104 enrolled 11 charts

Pancreatic Adenocarcinoma

NCT03126110 2025-08-14

Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic Malignancies

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

145 enrolled 47 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Neoplasm Metastasis, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT02872116 2025-08-07

CheckMate649

Phase 3 Completed

2,031 enrolled 19 charts 2 FDA

Adenocarcinoma Of Esophagus, Stomach Neoplasms

NCT03442569 2025-07-01

PhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC

56 enrolled 13 charts

Colonic Neoplasms

NCT04247165 2025-03-12

LAPTOP

55 enrolled

Pancreatic Neoplasms

NCT03058289 2025-02-27

IT-01

BreastGastrointestinalHead & NeckLymphoidSarcomaThoracic

111 enrolled 21 charts

Diabetes Mellitus, Insulin-Dependent, 12, Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Squamous Cell, Colonic Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Pancreatic Neoplasms, Sarcoma

NCT05302921 2025-01-01

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

CNSDermatologicGastrointestinalGenitourinarySarcoma

5 enrolled

Carcinoma, Hepatocellular, Melanoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma

NCT04340193 2024-11-26

CheckMate 74W

Phase 3 Completed

26 enrolled 15 charts

Liver Neoplasms

NCT03647969 2024-08-09

Modified FOLFOX Plus/Minus Nivolumab and Ipilimumab vs. FLOT Plus Nivolumab in Patients With Previously Untreated Advanced or Metastatic Gastric Cancer

262 enrolled

Adenocarcinoma of the Stomach

NCT03190265 2024-08-07

Study of CRS-207, Nivolumab, and Ipilimumab With or Without GVAX Pancreas Vaccine (With Cy) in Patients With Pancreatic Cancer

61 enrolled 11 charts

Adenocarcinoma, Carcinoma, Neoplasms, Pancreatic Neoplasms

NCT02923934 2024-07-24

A Phase II Trial of Ipilimumab and Nivolumab for the Treatment of Rare Cancers

EndocrineGastrointestinalNET

120 enrolled

Gastrointestinal Neoplasms, Neuroendocrine Tumors

NCT03510871 2024-07-08

Nivolumab Plus Ipilimumab as Neoadjuvant Therapy for Hepatocellular Carcinoma (HCC)

43 enrolled

Carcinoma, Hepatocellular

NCT03752398 2024-07-05

DUET-3

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

198 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Melanoma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Histiocytoma, Malignant Fibrous, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04124601 2024-04-23

CHINOREC

80 enrolled

Rectal Neoplasms

NCT01738139 2024-03-21

Ipilimumab and Imatinib Mesylate in Advanced Cancer

DermatologicGastrointestinalSarcoma

68 enrolled

Melanoma, Neoplasm Metastasis, Gastrointestinal Stromal Tumors

NCT03373188 2024-03-20

VX15/2503 and Immunotherapy in Resectable Pancreatic and Colorectal Cancer

10 enrolled

Pancreatic Neoplasms, Colorectal Neoplasms

NCT04721301 2023-10-17

Ipilimumab, Maraviroc and Nivolumab in Advanced Metastatic Colorectal and Pancreatic Cancer the LUMINESCENCE Trial

50 enrolled

Colorectal Cancer Metastatic

NCT02866383 2023-09-22

CheckPAC

160 enrolled

Biliary Tract Neoplasms, Pancreatic Neoplasms

NCT03639714 2023-09-13

A Study of a Personalized Neoantigen Cancer Vaccine

GastrointestinalGenitourinaryThoracic

29 enrolled

Diabetes Mellitus, Insulin-Dependent, 12, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Colorectal Neoplasms

NCT03953235 2023-09-13

A Study of a Personalized Cancer Vaccine Targeting Shared Neoantigens

39 enrolled

GastrointestinalThoracic

Diabetes Mellitus, Insulin-Dependent, 12, Carcinoma, Non-Small-Cell Lung, Pancreatic Neoplasms, Colorectal Neoplasms

NCT03222076 2023-07-10

Nivolumab With or Without Ipilimumab in Treating Patients With Resectable Liver Cancer

30 enrolled 9 charts

Carcinoma, Hepatocellular

NCT02935634 2023-06-09

FRACTION-GC

190 enrolled 25 charts

Advanced Gastric Cancer

NCT03507699 2023-04-18

Combined Immunotherapy and Radiosurgery for Metastatic Colorectal Cancer

19 enrolled

Diabetes Mellitus, Insulin-Dependent, 12, Colonic Neoplasms

NCT03101566 2022-10-28

Study of Nivolumab in Combination With Gemcitabine/Cisplatin or Ipilimumab for Patients With Advanced Unresectable Biliary Tract Cancer

75 enrolled 14 charts

Biliary Tract Neoplasms

NCT03416244 2022-09-29

RAMONA

66 enrolled

Esophageal Neoplasms

NCT03241173 2022-09-27

A Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic Malignancies

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

52 enrolled 25 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Ovarian Neoplasms, Stomach Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT02880020 2022-08-18

Nivolumab With or Without Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumor That Is Metastatic or Cannot Be Removed by Surgery

36 enrolled

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT03409848 2022-05-18

INTEGA

97 enrolled

Esophageal Neoplasms, Stomach Neoplasms

NCT03832621 2022-04-04

MAYA

135 enrolled

Colorectal Neoplasms

NCT00112580 2021-09-27

MDX-010 in Treating Patients With Stage IV Pancreatic Cancer That Cannot Be Removed By Surgery

27 enrolled 8 charts

Pancreatic Neoplasms

NCT02239900 2020-11-30

Ipilimumab and Stereotactic Body Radiation Therapy (SBRT) in Advanced Solid Tumors

GastrointestinalGenitourinaryThoracic

143 enrolled

GastrointestinalThoracic

Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT03695835 2020-07-22

NIRPA

Completed

27 enrolled

Adenocarcinoma, Urinary Bladder Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT01896869 2020-05-19

FOLFIRINOX Followed by Ipilimumab With Pancreatic Tumor Vaccine in Treatment of Metastatic Pancreatic Cancer

83 enrolled 16 charts

Diabetes Mellitus, Insulin-Dependent, 12, Pancreatic Neoplasms

NCT01473940 2020-03-06

Ipilimumab and Gemcitabine Hydrochloride in Treating Patients With Stage III-IV or Recurrent Pancreatic Cancer That Cannot Be Removed by Surgery

21 enrolled 14 charts

Pancreatic Neoplasms

NCT00836407 2020-02-24

Ipilimumab +/- Vaccine Therapy in Treating Patients With Locally Advanced, Unresectable or Metastatic Pancreatic Cancer

30 enrolled 9 charts

Diabetes Mellitus, Insulin-Dependent, 12, Pancreatic Neoplasms

NCT01643278 2017-01-10

Dasatinib and Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumors or Other Sarcomas That Cannot Be Removed by Surgery or Are Metastatic

29 enrolled

GastrointestinalSarcoma

Sarcoma, Gastrointestinal Stromal Tumors

NCT01585987 2016-05-17

An Efficacy Study in Gastric and Gastroesophageal Junction Cancer Comparing Ipilimumab Versus Standard of Care Immediately Following First Line Chemotherapy

143 enrolled 13 charts