Announcements Trials
Browse Landscape

Phase

Phase 2 5Phase 1 1

Status

Completed 6Terminated 4Withdrawn 1

Sponsor Class

NIH 6

Study Type

Interventional 6

Sponsor

Cancer Type

Gastrointestinal 6Breast 5Other hematologic neoplasm 4Lymphoid 4Tumor-Agnostic 3Thoracic 3Head & Neck 3Gynecologic 3Other solid neoplasm 2Sarcoma 1NET 1Myeloid 1Endocrine 1Dermatologic 1CNS 1

Conditions

Pancreatic Neoplasms 2Stomach Neoplasms 1Rectal Neoplasms 1Gallbladder Neoplasms 1Colorectal Neoplasms 1Colonic Neoplasms 1Carcinoma, Hepatocellular 1

Interventions

Fluorouracil 616Oxaliplatin 579Gemcitabine 492Capecitabine 445Leucovorin 427Irinotecan 390Bevacizumab 330Cisplatin 320Radiotherapy 245Cetuximab 215Sorafenib 167pembrolizumab 152Docetaxel 150Paclitaxel 140Nivolumab 128Albumin-Bound Paclitaxel 108130-nm albumin-bound paclitaxel 108Folfox protocol 101Panitumumab 95Erlotinib Hydrochloride 95Surgical Procedures, Operative 86regorafenib 84S 1 (combination) 81Drug Therapy 80Radiation 69Carboplatin 65Neoadjuvant Therapy 64Colonoscopy 64Radiosurgery 63Surveys and Questionnaires 60

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Completed × MK 2206 × Gastrointestinal × Clear all
NCT01802320 2019-09-20

Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

National Cancer Institute (NCI)

Phase 2 Completed
18 enrolled 7 charts
Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT01783171 2017-08-22

Dinaciclib and Akt Inhibitor MK2206 in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery

National Cancer Institute (NCI)

Phase 1 Completed
42 enrolled
Gastrointestinal

Pancreatic Neoplasms

NCT01425879 2016-06-17

MK2206 in Treating Patients With Advanced Refractory Biliary Cancer That Cannot Be Removed by Surgery

National Cancer Institute (NCI)

Phase 2 Completed
8 enrolled 8 charts
Gastrointestinal

Gallbladder Neoplasms, Carcinoma, Hepatocellular

NCT01658943 2016-03-09

S1115

National Cancer Institute (NCI)

Phase 2 Completed
137 enrolled 12 charts
Gastrointestinal

Pancreatic Neoplasms

NCT01260701 2016-01-18

Akt Inhibitor MK2206 in Treating Patients With Advanced Gastric or Gastroesophageal Junction Cancer

National Cancer Institute (NCI)

Phase 2 Completed
75 enrolled 9 charts
Gastrointestinal

Stomach Neoplasms

NCT01333475 2015-09-30

MK-2206 and AZD6244 in Patients With Advanced Colorectal Carcinoma

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
21 enrolled 11 charts
Gastrointestinal

Colorectal Neoplasms

Data powered by HemOnc (CC BY 4.0) Colophon âš¡