Announcements Trials
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Phase

Phase 2 2Phase 1 2

Status

Completed 2Withdrawn 1Terminated 1

Sponsor Class

INDUSTRY 5OTHER 4NETWORK 1

Study Type

Interventional 4

Sponsor

Cancer Type

Breast 10Thoracic 9Lymphoid 6Head & Neck 5Other solid neoplasm 4Gynecologic 4Genitourinary 4Gastrointestinal 4Other hematologic neoplasm 2Dermatologic 2CNS 2Tumor-Agnostic 1

Conditions

Colorectal Neoplasms 3Pancreatic Neoplasms 1Neoplasm Metastasis 1Lung Neoplasms 1Esophageal Neoplasms 1Cholangiocarcinoma 1Breast Neoplasms 1

Interventions

Oxaliplatin 1004Fluorouracil 800Capecitabine 764Gemcitabine 650Leucovorin 559Irinotecan 537Bevacizumab 513Radiotherapy 460Cisplatin 440Drug Therapy 298Cetuximab 280Surgical Procedures, Operative 228Paclitaxel 228S 1 (combination) 217pembrolizumab 205Docetaxel 199130-nm albumin-bound paclitaxel 196Nivolumab 193sintilimab 191Radiosurgery 190lenvatinib 180Folfox protocol 179Sorafenib 178Albumin-Bound Paclitaxel 173apatinib 170tislelizumab 161camrelizumab 160Neoadjuvant Therapy 158Blood Specimen Collection 154durvalumab 148

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
OTHER × NVP-BKM120 × Gastrointestinal × Clear all
NCT01806649 2021-10-11

BKM120 in Esophageal Squamous Cell Carcinoma After Failure of First Line Chemotherapy

Prince of Songkla University

Phase 2 Terminated
5 enrolled
Gastrointestinal

Esophageal Neoplasms

NCT01571024 2017-04-26

BKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic Cancer

UNC Lineberger Comprehensive Cancer Center

Phase 1 Completed
17 enrolled
Gastrointestinal

Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT01304602 2017-01-06

A Trial of Irinotecan and BKM120 in Previously Treated Advanced Colorectal Cancer

University of Kansas Medical Center

Phase 1 Completed
20 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT01501604 2015-09-17

BKM120 in Cancers With PIK3CA Activating Mutations

Massachusetts General Hospital

Phase 2 Withdrawn
BreastGastrointestinalThoracic

Breast Neoplasms, Lung Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

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