Clinical Trials

Colorectal Neoplasms

NCT06252649 2026-04-02

CodeBreaK 301

450 enrolled

Neoplasms, Colorectal Neoplasms

NCT06998940 2026-03-27

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

94 enrolled

Pancreatic Neoplasms

NCT05863195 2026-03-23

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

408 enrolled

Colorectal Neoplasms

NCT03384238 2026-03-17

Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery

Phase 1/2 Recruiting

27 enrolled

Pancreatic Adenocarcinoma

NCT05845450 2026-03-12

Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)

197 enrolled

Phase EARLY_PHASE1 Active not recruiting

Colorectal Neoplasms

NCT06011772 2026-03-11

EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer

2 enrolled

Phase EARLY_PHASE1 Not yet recruiting

Colonic Neoplasms

NCT07318389 2026-02-27

ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic Colorectal Cancer

100 enrolled

Colorectal Neoplasms

NCT07094113 2026-02-12

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

Phase 1 Recruiting

434 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT03693807 2026-02-06

A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma

35 enrolled 14 charts

Phase 3 Active not recruiting

Colorectal Neoplasms, Cholangiocarcinoma

NCT05198934 2026-02-06

CodeBreak300

160 enrolled 3 FDA

Colorectal Neoplasms

NCT04587128 2026-02-05

Early-Line Anti-EGFR Therapy to Facilitate Retreatment for Select Patients With mCRC

34 enrolled

Colorectal Neoplasms

NCT06268015 2026-02-05

BBOpCo

16 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT04787341 2026-02-02

PARERE

214 enrolled

Colorectal Neoplasms

NCT03087071 2026-01-12

Panitumumab With or Without Trametinib in Treating Patients With Stage IV Colorectal Cancer

59 enrolled

Colorectal Neoplasms

NCT03366155 2026-01-08

Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver

24 enrolled

Colorectal Neoplasms

NCT03983993 2026-01-05

NIPAVect

26 enrolled 8 charts

Colorectal Neoplasms

NCT06332079 2026-01-05

HAITI

Phase 2 Terminated

4 enrolled

Colorectal Cancer Metastatic

NCT06714357 2025-12-17

VICTORIA

130 enrolled

Colorectal Neoplasms

NCT06245356 2025-12-10

TRIFLUOX-DP

73 enrolled

CNSGastrointestinalHead & NeckMyeloidThoracic

Colorectal Neoplasms, Dihydropyrimidine Dehydrogenase Deficiency

NCT05786924 2025-11-20

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Phase 1/2 Recruiting

554 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Histiocytosis

NCT05576896 2025-10-20

Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory

43 enrolled

Colorectal Neoplasms

NCT01312857 2025-10-09

Study of Hepatic Arterial Infusion With Intravenous Irinotecan, 5FU and Leucovorin With or Without Panitumumab, in Patients With Wild Type RAS Who Have Resected Hepatic Metastases From Colorectal Cancer

75 enrolled 12 charts

Colorectal Neoplasms

NCT05694936 2025-09-18

Combining Sodium Valproate With Standard-of-care EGFR (Epidermal Growth Factor Receptor) Monoclonal Antibody Treatment in Patients With Metastatic Colorectal Cancer

90 enrolled

Colorectal Neoplasms

NCT06490536 2025-08-29

The Sagittarius Trial

700 enrolled

Colonic Neoplasms

NCT02885753 2025-07-09

OSCAR

348 enrolled

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT03442569 2025-07-01

PhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC

56 enrolled 13 charts

Colonic Neoplasms

NCT03186326 2025-06-29

SAMCO

132 enrolled

Colorectal Neoplasms

NCT03584711 2025-06-29

OPTIPRIME

118 enrolled

Colorectal Neoplasms

NCT06978400 2025-05-18

A Study of Dabrafenib Plus Cetuximab/Panitumumab With FOLFOX in the First Line of Therapy in People With Metastatic Colorectal Cancer

64 enrolled

Neoplasms, Colorectal Neoplasms

NCT03428958 2025-04-23

A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment

Phase 1/2 Completed

111 enrolled 22 charts

Colonic Neoplasms, Colorectal Neoplasms

NCT06194877 2025-04-20

A Study to Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Phase 1 Terminated

13 enrolled

Colorectal Neoplasms

NCT02980510 2025-02-20

PANIRINOX

219 enrolled

Colorectal Neoplasms

NCT02162563 2025-02-06

CAIRO5

Phase 3 Completed

530 enrolled

Colorectal Neoplasms

NCT01814501 2025-02-05

Panitumumab and Chemotherapy in Patients With Advanced Colorectal Cancer After Prior Therapy With Bevacizumab

16 enrolled 11 charts

Phase 1/2 Active not recruiting

Colonic Neoplasms, Rectal Neoplasms

NCT05121038 2024-12-17

CENDIFOX

50 enrolled

Phase 3 Active not recruiting

Colonic Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms

NCT03635021 2024-10-21

CR-SEQUENCE

419 enrolled

Colorectal Neoplasms

NCT03164655 2024-10-01

SULTAN

20 enrolled

Colorectal Cancer Metastatic

NCT04117945 2024-09-27

Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer

22 enrolled 17 charts

Colorectal Neoplasms

NCT03263429 2024-08-30

Novel PET/CT Imaging Biomarkers of CB-839 in Combination With Panitumumab and Irinotecan in Patients With Metastatic and Refractory RAS Wildtype Colorectal Cancer

Phase 1/2 Completed

29 enrolled 17 charts

Colorectal Neoplasms

NCT06575127 2024-08-28

Modified FOLFOXIRI Plus Target Therapy as a First Line Treatment for Advanced Colorectal Cancer a Prospective Phase Two Study

60 enrolled

Colonic Neoplasms, Neoplasms

NCT05084859 2024-08-09

A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Efficacy of Orally Administered SM08502 Combined With Hormonal Therapy or Chemotherapy in Subjects With Advanced Solid Tumors

Phase 1 Terminated

30 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT00788957 2024-08-07

Panitumumab Combination Study With Rilotumumab or Ganitumab in Wild-type Kirsten Rat Sarcoma Virus Oncogene Homolog (KRAS) Metastatic Colorectal Cancer (mCRC)

Phase 1/2 Completed

177 enrolled 31 charts

Colonic Neoplasms, Gastrointestinal Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT06509126 2024-07-19

IMPROVE-2

500 enrolled

Colorectal Neoplasms

NCT00891930 2024-07-17

Study to Evaluate Mechanisms of Acquired Resistance to Panitumumab

74 enrolled 15 charts

Colorectal Neoplasms

NCT03992456 2024-05-21

Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer

12 enrolled 16 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT03043950 2024-04-24

VALIDATE

Completed

647 enrolled

Colorectal Neoplasms

NCT01910610 2024-03-12

STRATEGIC-1

Phase 3 Unknown

464 enrolled