Clinical Trials

29 enrolled

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT04457284 2026-03-13

Temozolomide, Cisplatin, and Nivolumab in People With Colorectal Cancer

18 enrolled

Colorectal Adenocarcinoma

NCT03519412 2026-03-03

ARETHUSA

107 enrolled 14 charts

Colorectal Neoplasms, Microsatellite Instability

NCT04689347 2026-01-12

5FU/LV, Irinotecan, Temozolomide and Bevacizumab for MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer.

Phase 1/2 Recruiting

27 enrolled

Colorectal Neoplasms

NCT06630325 2026-01-07

A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer

GastrointestinalGenitourinaryGynecologic

30 enrolled

Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT06490536 2025-08-29

The Sagittarius Trial

Phase 3 Recruiting

700 enrolled

Colonic Neoplasms

NCT01205828 2025-02-12

ABT-888 and Temozolomide for Liver Cancer

Phase 2 Terminated

16 enrolled 11 charts

Carcinoma, Hepatocellular, Liver Neoplasms

NCT03556384 2024-11-04

Temozolomide (TMZ) in Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)

23 enrolled

GastrointestinalSarcoma

Hematoma, Subdural, Neoplasms, Gastrointestinal Stromal Tumors

NCT04893785 2024-06-18

CABOTEM

EndocrineGastrointestinalNET

35 enrolled

Gastro-enteropancreatic neuroendocrine tumor

NCT03351296 2024-05-08

BETTER2

140 enrolled

Pancreatic Neoplasms

NCT01525082 2024-02-06

Capecitabine, Temozolomide, and Bevacizumab for Metastatic or Unresectable Pancreatic Neuroendocrine Tumors

EndocrineGastrointestinal

20 enrolled 15 charts

Glucagonoma, Insulinoma, Pancreatic Neoplasms, Somatostatinoma, Gastrinoma, Carcinoma, Islet Cell

NCT04984733 2023-11-29

ELEVATE

18 enrolled

Esophageal Neoplasms, Neoplasms

NCT04166435 2023-09-06

TMZ + Olaparib for MGMT Hypermethylated Colorectal Cancer

11 enrolled 13 charts

Colorectal Neoplasms

NCT05136326 2023-03-01

CATARTIC

21 enrolled

Rectal Neoplasms

NCT05031975 2022-09-02

ERASE-TMZ

Phase 2 Unknown

35 enrolled

Colorectal Neoplasms

NCT03832621 2022-04-04

MAYA

135 enrolled

Colorectal Neoplasms

NCT02414009 2021-09-09

CAPTEM

82 enrolled

Colorectal Neoplasms

NCT01781403 2021-02-04

Preoperative CRT With Temozolomide Plus Capecitabine in Rectal Cancer

Phase 1 Completed

22 enrolled 5 charts

Rectal Neoplasms

NCT01051596 2019-04-02

A Study of ABT-888 in Combination With Temozolomide for Colorectal Cancer

75 enrolled 10 charts

DermatologicEndocrineGastrointestinalNET

Neoplasm Metastasis, Colorectal Neoplasms

NCT02831179 2017-09-28

Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor

Phase 1 Withdrawn

Non functioning pancreatic endocrine tumor, Adrenal Cortex Neoplasms, Carcinoid Tumor, Vipoma, Glucagonoma, Insulinoma, Pheochromocytoma, Somatostatinoma, Zollinger-Ellison Syndrome, Carcinoma, Merkel Cell, Carcinoma, Medullary, Neuroendocrine Tumors, Multiple Endocrine Neoplasia Type 1, Multiple Endocrine Neoplasia Type 2a, Multiple Endocrine Neoplasia Type 2b

NCT00869050 2016-07-25

Capecitabine and Temozolomide for Neuroendocrine Cancers