Clinical Trials Browser

Interventional × Topotecan × Gastrointestinal × Clear all

NCT04514497 2025-03-06

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer

Phase 1 Active not recruiting

28 enrolled

EndocrineGastrointestinalThoracic

Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT02390843 2020-04-03

AflacST1402

Phase 1 Completed

13 enrolled

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Renal Cell, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Rhabdoid Tumor

NCT01703910 2015-10-09

Study of Individualized Therapies Selection for Patients With Metastatic Colorectal Carcinoma According to the Therapeutic

Phase 2 Completed

29 enrolled

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms

NCT00215956 2013-12-23

A Phase I Study of Oral Topotecan as a Radiosensitizing Agent in Patients With Rectal Carcinoma

Phase 1 Completed

31 enrolled

Gastrointestinal

Rectal Neoplasms

NCT00002515 2013-06-24

Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer

Phase 2 Completed

CNSGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther solid neoplasmSarcoma

Testicular Germ Cell Tumor, Burkitt Lymphoma, Chondrosarcoma, Fibrosarcoma, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lymphoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Retinoblastoma, Sarcoma, Osteosarcoma, Testicular Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Dendritic Cell Sarcoma, Interdigitating, Desmoplastic Small Round Cell Tumor

NCT00002625 2013-02-11

Topotecan and Radiation Therapy in Treating Patients With Solid Tumors or Lymphoma

Phase 1 Completed

5 enrolled

DermatologicGastrointestinalLymphoidOther hematologic neoplasmThoracic

Burkitt Lymphoma, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Hodgkin Disease, Lung Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Small Cell Lung Carcinoma

NCT00193167 2011-05-03

Weekly Topotecan in Patients Treated for Metastatic Colorectal Cancer

Phase 2 Completed

40 enrolled

Gastrointestinal

Colonic Neoplasms

NCT00252889 2009-01-27

Doxil Topotecan Doublet Cancer Study

Phase 1 Completed

20 enrolled

GastrointestinalHead & NeckThoracic

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Head and Neck Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Stomach Neoplasms, Small Cell Lung Carcinoma