Announcements Trials
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Phase

Phase 1 2Phase EARLY_PHASE1 1Phase 1/2 1

Status

Withdrawn 1Recruiting 1Not yet recruiting 1Active not recruiting 1

Sponsor Class

INDUSTRY 9OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 7Gastrointestinal 4Other solid neoplasm 1CNS 1

Conditions

Colorectal Neoplasms 3Pancreatic Neoplasms 1Colonic Neoplasms 1

Interventions

Oxaliplatin 1004Fluorouracil 800Capecitabine 765Gemcitabine 651Leucovorin 559Irinotecan 537Bevacizumab 513Radiotherapy 460Cisplatin 441Drug Therapy 298Cetuximab 280Surgical Procedures, Operative 229Paclitaxel 228S 1 (combination) 218pembrolizumab 206Docetaxel 199130-nm albumin-bound paclitaxel 196Nivolumab 193sintilimab 191Radiosurgery 190lenvatinib 181Folfox protocol 179Sorafenib 178Albumin-Bound Paclitaxel 173apatinib 170tislelizumab 161camrelizumab 160Neoadjuvant Therapy 158Blood Specimen Collection 154durvalumab 148

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
OTHER × adagrasib × Gastrointestinal × Clear all
NCT06412198 2026-03-06

A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

M.D. Anderson Cancer Center

Phase 1/2 Recruiting
31 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT05722327 2026-03-04

Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer

M.D. Anderson Cancer Center

Phase 1 Active not recruiting
24 enrolled
Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT07318389 2026-02-27

ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic Colorectal Cancer

M.D. Anderson Cancer Center

Phase EARLY_PHASE1 Not yet recruiting
100 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT05634525 2025-07-25

Phase Ib Trial of the KRASG12C Inhibitor Adagrasib (MRTX849) in KRAS G12C Mutant Metastatic Pancreatic Cancer Patients

M.D. Anderson Cancer Center

Phase 1 Withdrawn
Gastrointestinal

Pancreatic Neoplasms

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