Announcements Trials
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Phase

Phase 2 3Phase 3 1Phase 1/2 1

Status

Completed 5Withdrawn 1

Sponsor Class

OTHER 2INDUSTRY 2NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

Gastrointestinal 5Gynecologic 4Genitourinary 3Thoracic 1Sarcoma 1Other solid neoplasm 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1Head & Neck 1Dermatologic 1CNS 1Breast 1

Conditions

Pancreatic Neoplasms 2Stomach Neoplasms 1Rectal Neoplasms 1Liver Neoplasms 1Colorectal Neoplasms 1Colonic Neoplasms 1

Interventions

Fluorouracil 616Oxaliplatin 579Gemcitabine 492Capecitabine 445Leucovorin 427Irinotecan 390Bevacizumab 330Cisplatin 320Radiotherapy 245Cetuximab 215Sorafenib 167pembrolizumab 152Docetaxel 150Paclitaxel 140Nivolumab 128Albumin-Bound Paclitaxel 108130-nm albumin-bound paclitaxel 108Folfox protocol 101Panitumumab 95Erlotinib Hydrochloride 95Surgical Procedures, Operative 86regorafenib 84S 1 (combination) 81Drug Therapy 80Radiation 69Carboplatin 65Neoadjuvant Therapy 64Colonoscopy 64Radiosurgery 63Surveys and Questionnaires 60

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × irofulven × Gastrointestinal × Clear all
NCT00374660 2021-12-08

Study of Irofulven in Combination With Oxaliplatin in Patients With Advanced Solid Tumors

Eisai Inc.

Phase 1/2 Completed
63 enrolled
Gastrointestinal

Liver Neoplasms

NCT00003441 2018-10-25

Irofulven in Treating Patients With Metastatic Colorectal Cancer

M.D. Anderson Cancer Center

Phase 2 Completed
26 enrolled
Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00062257 2013-05-15

Irofulven in Treating Patients With Recurrent or Metastatic Gastric Cancer

National Cancer Institute (NCI)

Phase 2 Completed
Gastrointestinal

Stomach Neoplasms

NCT00033735 2012-12-24

Irofulven Compared With Fluorouracil in Treating Patients With Pancreatic Cancer

Eisai Inc.

Phase 3 Completed
158 enrolled
Gastrointestinal

Pancreatic Neoplasms

NCT00003760 2012-08-09

Irofulvene in Treating Patients With Stage III or Stage IV Pancreatic Cancer

The University of Texas Health Science Center at San Antonio

Phase 2 Completed
3 enrolled
Gastrointestinal

Pancreatic Neoplasms

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