Announcements Trials
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Phase

Phase 2 2Phase 3 1Phase 1 1

Status

Completed 4

Sponsor Class

INDUSTRY 4

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 7Gastrointestinal 4Tumor-Agnostic 2Other solid neoplasm 1CNS 1Breast 1

Conditions

Stomach Neoplasms 2Colorectal Neoplasms 1Carcinoma, Hepatocellular 1

Interventions

Oxaliplatin 1439Fluorouracil 1319Capecitabine 1114Gemcitabine 1057Leucovorin 939Bevacizumab 847Irinotecan 830Cisplatin 676Radiotherapy 560Cetuximab 482pembrolizumab 435Paclitaxel 401Drug Therapy 358Nivolumab 350130-nm albumin-bound paclitaxel 328Docetaxel 290Sorafenib 288S 1 (combination) 279Folfox protocol 266Albumin-Bound Paclitaxel 263Surgical Procedures, Operative 257lenvatinib 222sintilimab 218tislelizumab 214durvalumab 212regorafenib 209Magnetic Resonance Spectroscopy 205apatinib 204Radiosurgery 204Neoadjuvant Therapy 190

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
onartuzumab × Gastrointestinal × Clear all
NCT01418222 2017-05-30

FOLFOX/Bevacizumab With Onartuzumab (MetMAb) Versus Placebo as First-Line Treatment in Patients With Metastatic Colorectal Cancer

Genentech, Inc.

Phase 2 Completed
194 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT01662869 2016-11-02

A Study of Onartuzumab in Combination With mFOLFOX6 in Participants With Metastatic HER2-Negative and MET-Positive Gastroesophageal Cancer

Hoffmann-La Roche

Phase 3 Completed
564 enrolled
Gastrointestinal

Stomach Neoplasms

NCT01897038 2016-11-02

A Safety, Tolerability, and Pharmacokinetics Study of Onartuzumab as Single Agent or in Combination With Sorafenib in Participants With Advanced Hepatocellular Carcinoma

Hoffmann-La Roche

Phase 1 Completed
9 enrolled
Gastrointestinal

Carcinoma, Hepatocellular

NCT01590719 2016-08-09

A Study of Onartuzumab (MetMAb) in Combination With mFOLFOX6 in Patients With Metastatic Human Epidermal Growth Factor Receptor 2 (HER2) Negative Gastroesophageal Cancer

Hoffmann-La Roche

Phase 2 Completed
123 enrolled
Gastrointestinal

Stomach Neoplasms

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