Announcements Trials
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Phase

Phase 2 2Phase 3 1Phase 1 1

Status

Completed 4

Sponsor Class

INDUSTRY 4

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 6Gastrointestinal 4Tumor-Agnostic 2Other solid neoplasm 1CNS 1Breast 1

Conditions

Stomach Neoplasms 2Colorectal Neoplasms 1Carcinoma, Hepatocellular 1

Interventions

Gemcitabine 302Fluorouracil 296Oxaliplatin 269Bevacizumab 267Capecitabine 233Leucovorin 229pembrolizumab 215Irinotecan 185Cisplatin 142Cetuximab 142Nivolumab 131Paclitaxel 117130-nm albumin-bound paclitaxel 117Sorafenib 86Albumin-Bound Paclitaxel 75Docetaxel 65regorafenib 64atezolizumab 64IFL protocol 61Folfox protocol 61Trastuzumab 55Panitumumab 47durvalumab 46Ramucirumab 43Injections 43Sunitinib 41Drug Therapy 41Carboplatin 40trifluridine tipiracil drug combination 38lenvatinib 38

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
INDUSTRY × onartuzumab × Gastrointestinal × Clear all
NCT01418222 2017-05-30

FOLFOX/Bevacizumab With Onartuzumab (MetMAb) Versus Placebo as First-Line Treatment in Patients With Metastatic Colorectal Cancer

Genentech, Inc.

Phase 2 Completed
194 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT01662869 2016-11-02

A Study of Onartuzumab in Combination With mFOLFOX6 in Participants With Metastatic HER2-Negative and MET-Positive Gastroesophageal Cancer

Hoffmann-La Roche

Phase 3 Completed
564 enrolled
Gastrointestinal

Stomach Neoplasms

NCT01897038 2016-11-02

A Safety, Tolerability, and Pharmacokinetics Study of Onartuzumab as Single Agent or in Combination With Sorafenib in Participants With Advanced Hepatocellular Carcinoma

Hoffmann-La Roche

Phase 1 Completed
9 enrolled
Gastrointestinal

Carcinoma, Hepatocellular

NCT01590719 2016-08-09

A Study of Onartuzumab (MetMAb) in Combination With mFOLFOX6 in Patients With Metastatic Human Epidermal Growth Factor Receptor 2 (HER2) Negative Gastroesophageal Cancer

Hoffmann-La Roche

Phase 2 Completed
123 enrolled
Gastrointestinal

Stomach Neoplasms

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