Announcements Trials
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Phase

Phase 2 2Phase 1/2 1

Status

Completed 2No longer available 1Active not recruiting 1

Sponsor Class

INDUSTRY 4OTHER 3

Study Type

Interventional 3Expanded_access 1

Sponsor

Cancer Type

Gastrointestinal 4Other hematologic neoplasm 1Genitourinary 1

Conditions

Colorectal Neoplasms 4

Interventions

Gemcitabine 302Fluorouracil 296Oxaliplatin 269Bevacizumab 267Capecitabine 233Leucovorin 229pembrolizumab 215Irinotecan 185Cisplatin 142Cetuximab 142Nivolumab 131Paclitaxel 117130-nm albumin-bound paclitaxel 117Sorafenib 86Albumin-Bound Paclitaxel 75Docetaxel 65regorafenib 64atezolizumab 64IFL protocol 61Folfox protocol 61Trastuzumab 55Panitumumab 47durvalumab 46Ramucirumab 43Injections 43Sunitinib 41Drug Therapy 41Carboplatin 40trifluridine tipiracil drug combination 38lenvatinib 38

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
INDUSTRY × onvansertib × Gastrointestinal × Clear all
NCT06106308 2026-01-12

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation

Cardiff Oncology

Phase 2 Active not recruiting
113 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT03829410 2025-03-04

Onvansertib in Combination With FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer Patients With a KRAS Mutation

Cardiff Oncology

Phase 1/2 Completed
68 enrolled 21 charts
Gastrointestinal

Colorectal Neoplasms

NCT05593328 2025-01-10

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab Versus FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer in Participants With a Kirsten Rat Sarcoma Virus Gene (KRAS) or Neuroblastoma-RAS (NRAS) Mutation

Cardiff Oncology

Phase 2 Completed
23 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT04446793 2024-02-12

Expanded Access of Onvansertib With FOLFIRI and Bevacizumab for the Second-Line Treatment of Participants With KRAS-Mutated Metastatic Colorectal Cancer

Cardiff Oncology

No longer available
Gastrointestinal

Colorectal Neoplasms

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