Announcements Trials
Browse Landscape

Phase

Phase 2 4Phase 1 1

Status

Completed 4Unknown 1

Sponsor Class

INDUSTRY 3OTHER_GOV 1OTHER 1

Study Type

Interventional 5

Sponsor

Cancer Type

Gynecologic 8Genitourinary 7Sarcoma 5Gastrointestinal 5CNS 3Breast 3Tumor-Agnostic 2Thoracic 1Other solid neoplasm 1Other hematologic neoplasm 1Dermatologic 1

Conditions

Colorectal Neoplasms 3Gastrointestinal Neoplasms 2Stomach Neoplasms 1Rectal Neoplasms 1Ovarian Neoplasms 1Neoplasms 1Neoplasm Metastasis 1Melanoma 1Kidney Neoplasms 1Colonic Neoplasms 1Carcinoma 1Advanced Hepatocellular Carcinoma 1

Interventions

Oxaliplatin 1413Fluorouracil 1301Capecitabine 1087Gemcitabine 1045Leucovorin 932Irinotecan 818Bevacizumab 804Cisplatin 669Radiotherapy 536Cetuximab 470pembrolizumab 428Paclitaxel 390Nivolumab 337130-nm albumin-bound paclitaxel 325Drug Therapy 314Docetaxel 287S 1 (combination) 274Sorafenib 266Folfox protocol 261Albumin-Bound Paclitaxel 259sintilimab 211durvalumab 210Surgical Procedures, Operative 204tislelizumab 203Radiosurgery 202lenvatinib 201apatinib 200Carboplatin 187Magnetic Resonance Spectroscopy 183regorafenib 181

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × trebananib × Gastrointestinal × Clear all
NCT03239145 2026-03-12

Pembrolizumab (Anti-PD-1) and AMG386 (Angiopoietin-2 (Ang-2) in Patients With Advanced Solid Tumor

Dana-Farber Cancer Institute

Phase 1 Completed
62 enrolled 17 charts
DermatologicGastrointestinalGenitourinaryGynecologic

Kidney Neoplasms, Melanoma, Ovarian Neoplasms, Colorectal Neoplasms

NCT00872014 2016-04-04

A Study of the Effectiveness and Safety of AMG 386 and Sorafenib to Treat Advanced or Inoperable Hepatocellular Cancer

Amgen

Phase 2 Completed
60 enrolled
Gastrointestinal

Advanced Hepatocellular Carcinoma

NCT00752570 2015-09-02

A Phase 2, Randomized, Double Blind, Placebo Controlled Study of AMG 386 in Combination With FOLFIRI in Subjects With Previously Treated Metastatic Colorectal Carcinoma

Amgen

Phase 2 Completed
144 enrolled
Gastrointestinal

Carcinoma, Colonic Neoplasms, Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00583674 2014-05-07

Phase 2 Study of AMG 386 (20060439) in Combination With Cisplatin & Capecitabine in Subjects With Metastatic Gastric, Gastroesophageal Junction, or Distal Esophageal Adenocarcinoma

Amgen

Phase 2 Completed
171 enrolled
Gastrointestinal

Gastrointestinal Neoplasms, Stomach Neoplasms

NCT01249521 2010-11-30

Vengeance

Austin Health

Phase 2 Unknown
40 enrolled
Gastrointestinal

Colorectal Neoplasms

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