Announcements Trials
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Phase

Phase 2 3Phase 1 1

Status

Completed 4

Sponsor Class

INDUSTRY 3NETWORK 1

Study Type

Interventional 4

Sponsor

Cancer Type

Other solid neoplasm 6Thoracic 5Gastrointestinal 4Gynecologic 3Tumor-Agnostic 1Sarcoma 1Lymphoid 1Head & Neck 1Genitourinary 1Endocrine 1CNS 1

Conditions

Colorectal Neoplasms 2Colonic Neoplasms 2Thyroid Neoplasms 1Thyroid Carcinoma, Anaplastic 1Thyroid Cancer, Papillary 1Squamous Cell Carcinoma of Head and Neck 1Salivary Gland Neoplasms 1Parathyroid Neoplasms 1Kidney Neoplasms 1Head and Neck Neoplasms 1Esthesioneuroblastoma, Olfactory 1Carcinoma, Renal Cell 1Carcinoma, Medullary 1Carcinoma, Hepatocellular 1Adenocarcinoma, Follicular 1

Interventions

Oxaliplatin 1439Fluorouracil 1319Capecitabine 1114Gemcitabine 1057Leucovorin 939Bevacizumab 847Irinotecan 830Cisplatin 676Radiotherapy 560Cetuximab 482pembrolizumab 435Paclitaxel 401Drug Therapy 358Nivolumab 350130-nm albumin-bound paclitaxel 328Docetaxel 290Sorafenib 288S 1 (combination) 279Folfox protocol 266Albumin-Bound Paclitaxel 263Surgical Procedures, Operative 257lenvatinib 222sintilimab 218tislelizumab 214durvalumab 212regorafenib 209Magnetic Resonance Spectroscopy 205apatinib 204Radiosurgery 204Neoadjuvant Therapy 190

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
tumor necrosis factor-alpha, CNGRC fusion protein, human × Gastrointestinal × Clear all
NCT00483080 2019-01-16

Study of NGR-hTNF as Single Agent in Patients Affected by Colorectal Cancer (CRC)

AGC Biologics S.p.A.

Phase 2 Completed
46 enrolled
Gastrointestinal

Colorectal Neoplasms

NCT00484211 2014-05-30

Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Hepatocellular Carcinoma (HCC)

AGC Biologics S.p.A.

Phase 2 Completed
40 enrolled
Gastrointestinal

Carcinoma, Hepatocellular

NCT00675012 2014-05-30

NGR-hTNF Administered in Combination With a Standard Oxaliplatin Based Regimen in Patients With Metastatic Colorectal Cancer

AGC Biologics S.p.A.

Phase 2 Completed
24 enrolled
Gastrointestinal

Colonic Neoplasms

NCT00098943 2012-09-24

NGR-TNF in Treating Patients With Advanced Solid Tumors

European Organisation for Research and Treatment of Cancer - EORTC

Phase 1 Completed
70 enrolled
CNSEndocrineGastrointestinalGenitourinaryHead & Neck

Squamous Cell Carcinoma of Head and Neck, Thyroid Cancer, Papillary, Carcinoma, Renal Cell, Colonic Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Parathyroid Neoplasms, Salivary Gland Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Adenocarcinoma, Follicular, Carcinoma, Medullary, Esthesioneuroblastoma, Olfactory, Thyroid Carcinoma, Anaplastic

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