Clinical Trials Browser

Phase 2/3 × Recruiting × Gastrointestinal × Clear all

NCT06203600 2026-04-17

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

Phase 2/3 Recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus

NCT07537998 2026-04-17

Antegrade Intestinal Fluid Reinfusion for Prevention of Low Anterior Resection Syndrome After Low Anterior Resection: a Single-Center, Prospective Randomized Controlled Trial.

Phase 2/3 Recruiting

Gastrointestinal

Low Anterior Resection Syndrome, Rectal Neoplasms

NCT07490262 2026-04-16

A Study to Evaluate the Efficacy and Safety of IBI310 and Sintilimab Combination Therapy in Patients With Hepatocellular Carcinoma as First-line Treatment.

Phase 2/3 Recruiting

Gastrointestinal

Carcinoma, Hepatocellular

NCT07392892 2026-04-13

A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

Phase 2/3 Recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Stomach Neoplasms

NCT07293468 2026-04-09

BIIRTH

Phase 2/3 Recruiting

Gastrointestinal

Carcinoma, Hepatocellular

NCT06989437 2026-04-08

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

Phase 2/3 Recruiting

Gastrointestinal

Anorexia, Cachexia, Fatigue, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Weight Loss

NCT05174169 2026-04-02

CIRCULATE-US

Phase 2/3 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT07221149 2026-04-02

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

Phase 2/3 Recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Stomach Neoplasms

NCT07505472 2026-04-01

STARS-RC10

Phase 2/3 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT07076121 2026-03-31

A Study Comparing BMS-986504 in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)

Phase 2/3 Recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT07221357 2026-03-31

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT05179889 2026-03-19

Adjuvant mFOLFIRINOX for High-risk Stage III Colon Cancer

Phase 2/3 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT06721520 2026-02-25

EMPTY

Phase 2/3 Recruiting

Gastrointestinal

Esophageal Achalasia, Esophageal Diseases, Esophageal Motility Disorders, Gastroparesis

NCT03051464 2026-02-17

Morpheus

Phase 2/3 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT07044453 2026-02-17

PANACHE 02

Phase 2/3 Recruiting

Gastrointestinal

Resected Pancreatic Adenocarcinoma

NCT04749108 2026-02-05

GRECCAR14

Phase 2/3 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT06904170 2026-02-03

ALICE

Phase 2/3 Recruiting

Gastrointestinal

Carcinoma, Hepatocellular

NCT06312982 2026-01-13

A Series of Neoadjuvant Chemoradiotherapy Combined With Immunotherapy for Locally Advanced Rectal Cancer

Phase 2/3 Recruiting

Gastrointestinal

Locally Advanced Rectal Carcinoma

NCT04353375 2025-12-31

HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma

Phase 2/3 Recruiting

GastrointestinalOther solid neoplasm

Advanced Intrahepatic Cholangiocarcinoma

NCT06361888 2025-12-30

A Phase II/III Trial to Evaluate the Efficacy and Safety of Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer

Phase 2/3 Recruiting

Gastrointestinal

Pancreatic Neoplasms

NCT07285850 2025-12-16

ABATE-MASLD

Phase 2/3 Recruiting

Gastrointestinal

Carcinoma, Hepatocellular

NCT07272772 2025-12-09

Colon Cancer Diagnosis With FAPI-PET Imaging

Phase 2/3 Recruiting

Gastrointestinal

Colonic Neoplasms

NCT06851663 2025-12-08

Trop2-targeted immunoPET Imaging of Solid Tumors

Phase 2/3 Recruiting

GastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Nasopharyngeal Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Thyroid Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06783140 2025-12-05

PLATINUM-CAN

Phase 2/3 Recruiting

Gastrointestinal

Neoplasm Metastasis, Pancreatic Neoplasms

NCT05786716 2025-12-02

DETERMINE

Phase 2/3 Recruiting

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther hematologic neoplasmThoracic

Urinary Bladder Neoplasms, Gallbladder Neoplasms, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Skin Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms

NCT05768178 2025-11-24

DETERMINE

Phase 2/3 Recruiting

CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT05770102 2025-11-24

DETERMINE

Phase 2/3 Recruiting

DermatologicGastrointestinalGynecologicLymphoid

Lymphoproliferative Disorders, Melanoma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Colorectal Neoplasms, Endometrial Neoplasms

NCT06988475 2025-11-24

DETERMINE

Phase 2/3 Recruiting

CNSGastrointestinalOther hematologic neoplasmSarcoma

Glioma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neuroblastoma, Sarcoma, Stomach Neoplasms, Hematologic Neoplasms

NCT06007846 2025-09-30

A Prospective Study of Memantine in Patients With Cirrhosis and Liver Cancer

Phase 2/3 Recruiting

Gastrointestinal

Fibrosis, Carcinoma, Hepatocellular

NCT06644937 2025-09-23

Single-arm Clinical Trial of TACE in Combination With Icaritin as Adjuvant Therapy After Surgery in Patients With Hepatocellular Carcinoma at High Risk of Recurrence

Phase 2/3 Recruiting

Gastrointestinal

Carcinoma, Hepatocellular

NCT07165886 2025-09-10

Sirolimus for Injection (Albumin Bound) Combined With Octreotide Long-acting Injection in Patients With Metastatic Gastroenteropancreatic Neuroendocrine Tumors

Phase 2/3 Recruiting

EndocrineGastrointestinalNET

Gastroenteropancreatic Neuroendocrine Tumors

NCT06826079 2025-09-09

SNCCTGC

Phase 2/3 Recruiting

Gastrointestinal

Stomach Neoplasms

NCT07018661 2025-08-27

PLASTIC-3

Phase 2/3 Recruiting

Gastrointestinal

Stomach Neoplasms

NCT06109272 2025-08-15

LIVIGNO-2

Phase 2/3 Recruiting

Gastrointestinal

Carcinoma, Hepatocellular

NCT06095141 2025-08-07

PTCA199-6

Phase 2/3 Recruiting

Gastrointestinal

Pancreatic Adenocarcinoma

NCT06958419 2025-08-07

Node-Sparing Short-Course Radiotherapy Plus Chemotherapy, Bevacizumab and PD-1 Inhibitor in Metastatic pMMR/MSS Colorectal Cancer (MODIFI-CRC)

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06958432 2025-08-07

Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)

Phase 2/3 Recruiting

Gastrointestinal

Rectal Neoplasms

NCT07098598 2025-08-01

Pancreatic Cancer Diagnosis With FAPI-PET Imaging

Phase 2/3 Recruiting

Gastrointestinal

Disease, Pancreatic Neoplasms

NCT06441565 2025-07-30

Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06232434 2025-06-22

ИНТЕЛОН-02

Phase 2/3 Recruiting

Gastrointestinal

Gastric Cancer With Peritoneal Dissemination

NCT06280495 2025-05-30

Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients

Phase 2/3 Recruiting

Gastrointestinal

Colorectal Neoplasms

NCT06028737 2025-05-06

OCTASUR

Phase 2/3 Recruiting

Gastrointestinal

Gastrointestinal Neoplasms, Neoplasms, Stomach Neoplasms

NCT05065957 2025-04-30

Study of Combination Therapy of D07001-Softgel Capsules and Xeloda/TS-1 in Subjects With Advanced Biliary Tract Cancer

Phase 2/3 Recruiting

Gastrointestinal

Biliary Tract Neoplasms

NCT06214572 2025-04-11

RUGB

Phase 2/3 Recruiting

Gastrointestinal

Biliary Tract Neoplasms, Gallbladder Neoplasms

NCT06355427 2025-04-11

FAPIChol

Phase 2/3 Recruiting

Gastrointestinal

Cholangiocarcinoma

NCT06907602 2025-04-02

ONTRESCC

Phase 2/3 Recruiting

Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT05504265 2025-03-20

Perioperative Analgesia Modes in Minimally Invasive Esophagectomy

Phase 2/3 Recruiting

Gastrointestinal

Esophageal Neoplasms

NCT06037980 2025-02-17

PURITY

Phase 2/3 Recruiting

Gastrointestinal

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT06782412 2025-02-07

FAPIDO

Phase 2/3 Recruiting

Gastrointestinal

Esophageal Neoplasms, Neoplasms, Stomach Neoplasms

NCT06504732 2025-01-20

To Evaluate IAH0968 in Combination With CAPEOX in HER2-positive Gastric Cancer

Phase 2/3 Recruiting

Gastrointestinal

Stomach Neoplasms