Clinical Trials Browser

Lymphadenopathy, Immunoglobulin Light-chain Amyloidosis, Constipation, Diarrhea, Gastrointestinal Hemorrhage, Hepatomegaly, Macroglossia, Nausea, Purpura

NCT02205047 2025-07-31

INNOVATION

Phase 2 Completed

172 enrolled

Gastrointestinal

Stomach Neoplasms

NCT06441747 2025-07-29

Phase II Study of the Combination of Durvalumab (MEDI4736) (PDL1 Inhibitor) and Olaparib (PARP Inhibitor) in Advanced Cholangiocarcinoma After Initial Chemotherapy and Durvalumab (BIL-PPP)

Phase 2 Recruiting

40 enrolled

Gastrointestinal

Cholangiocarcinoma

NCT06290505 2025-07-23

PALEO

Phase 2 Recruiting

54 enrolled

Gastrointestinal

Esophageal Neoplasms

NCT07058012 2025-07-10

EMPIRE

Phase 2 Not yet recruiting

79 enrolled

Gastrointestinal

Colonic Neoplasms

NCT00324415 2025-05-30

Combined Modality Therapy for Patients With With HIV and Stage I, Stage II, or Stage III Anal Cancer

Phase 2 Completed

45 enrolled 17 charts

Gastrointestinal

Anal Canal Carcinoma, Anus Neoplasms

NCT06094140 2024-12-03

NEO-IMPACT

Phase 2 Active not recruiting

20 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT05042128 2024-10-22

ASCEND

Phase 2 Active not recruiting

158 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT04205955 2024-05-01

Testing Diet Intervention Versus Non-Diet Intervention for Management of Bowel Symptoms in Rectal Cancer Survivors

Phase 2 Completed

95 enrolled 30 charts

Gastrointestinal

Rectal Neoplasms

NCT00321828 2024-03-21

Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colon Cancer That Cannot Be Removed By Surgery

Phase 2 Completed

90 enrolled 6 charts

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT04617067 2024-03-06

Paricalcitol Trial: Phase II, Open Label Clinical Trial of Paricalcitol in Combination With Gemcitabine/ Nab-Paclitaxel Therapy in Advanced Pancreatic Cancer

Phase 2 Completed

15 enrolled

Gastrointestinal

Advanced Pancreatic Cancer

NCT03443856 2024-01-05

VESTIGE

Phase 2 Active not recruiting

197 enrolled

Gastrointestinal

Gastric and Esophagogastric Junction Adenocarcinoma

NCT02870920 2023-12-08

Durvalumab and Tremelimumab and Best Supportive Care vs Best Supportive Care in Patients With Advanced Colorectal Cancer

Phase 2 Completed

180 enrolled 13 charts

Gastrointestinal

Colorectal Neoplasms

NCT03260712 2023-11-03

Pembrolizumab in Biliary Tract Cancer

Phase 2 Completed

50 enrolled

Gastrointestinal

Biliary Tract Neoplasms, Gallbladder Neoplasms, Neoplasm Metastasis

NCT01622543 2023-08-23

Reolysin in Combination With FOLFOX6 and Bevacizumab or FOLFOX6 and Bevacizumab Alone in Metastatic Colorectal Cancer

Phase 2 Completed

109 enrolled 13 charts

Gastrointestinal

Colorectal Neoplasms

NCT00095992 2023-08-04

SB-715992 in Treating Patients With Locally Advanced, Recurrent, or Metastatic Liver Cancer

Phase 2 Completed

15 enrolled

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms

NCT02365441 2023-07-07

ALT GIST

Phase 2 Unknown

78 enrolled

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT00003298 2023-07-06

Chemotherapy, Surgery, and Radiation Therapy in Treating Patients With Gastric Cancer

Phase 2 Completed

39 enrolled 7 charts

Gastrointestinal

Stomach Neoplasms

NCT00042939 2023-07-06

Irinotecan and Docetaxel With or Without Cetuximab in Treating Patients With Metastatic Pancreatic Cancer

Phase 2 Completed

94 enrolled 10 charts

Gastrointestinal

Pancreatic Neoplasms

NCT00003907 2023-07-05

Chemoembolization in Treating Patients With Primary Liver Cancer or Metastases to the Liver

Phase 2 Completed

50 enrolled 8 charts

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis

NCT00098787 2023-07-05

Bevacizumab and Oxaliplatin Combined With Irinotecan or Leucovorin and Fluorouracil in Treating Patients With Metastatic or Recurrent Colorectal Cancer

Phase 2 Completed

247 enrolled 10 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00551759 2023-07-03

Chemotherapy, Radiation Therapy, and Cetuximab Followed by Surgery, Docetaxel, and Cetuximab in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer

Phase 2 Terminated

22 enrolled 5 charts

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT00063986 2023-06-29

Esophagectomy in Treating Patients With High-Grade Dysplasia of the Esophagus or Stage I, Stage II, or Stage III Esophageal Cancer

Phase 2 Completed

110 enrolled 13 charts

Gastrointestinal

Esophageal Neoplasms

NCT00316888 2023-06-29

Cetuximab, Cisplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Anal Cancer

Phase 2 Completed

63 enrolled 10 charts

Gastrointestinal

Anal Canal Carcinoma, Anus Neoplasms

NCT00033657 2023-06-28

Radiation Therapy and Chemotherapy Before and After Surgery in Treating Patients With Esophageal Cancer

Phase 2 Completed

97 enrolled 9 charts

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT01079780 2023-06-28

Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy

Phase 2 Completed

136 enrolled 13 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00002650 2023-06-22

High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed

Phase 2 Completed

80 enrolled

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00003237 2023-06-22

Combination Chemotherapy After Surgery in Treating Patients With Cancer of the Esophagus or Stomach

Phase 2 Completed

55 enrolled

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT02560298 2023-06-22

InterAACT

Phase 2 Unknown

91 enrolled

Gastrointestinal

Anal Canal Carcinoma, Anus Neoplasms

NCT00002997 2023-06-15

Cryosurgery in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00003810 2023-06-15

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas

Phase 2 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT00003864 2023-06-15

Docetaxel Plus Carboplatin in Treating Patients With Advanced Cancer of the Esophagus

Phase 2 Completed

Gastrointestinal

Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms

NCT00004860 2023-06-15

Fluorouracil-Uracil and Leucovorin in Treating Elderly Patients With Metastatic Colorectal Cancer

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00049348 2023-06-15

Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer

Phase 2 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT03007407 2022-12-05

Study of Durvalumab and Tremelimumab After Radiation for Microsatellite Stable Metastatic Colorectal Cancer Progressing on Chemotherapy

Phase 2 Completed

33 enrolled 8 charts

Gastrointestinal

Colorectal Cancer Metastatic

NCT05178576 2022-11-04

A Single Arm Phase II Study to Evaluate Treatment With Gevokizumab in Patients With Stage II/III Colon Cancer Who Are ctDNA-positive After Curative Surgery and Adjuvant Chemotherapy

Phase 2 Withdrawn

Gastrointestinal

Colonic Neoplasms

NCT02562716 2022-10-19

S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery

Phase 2 Completed

147 enrolled 16 charts

Gastrointestinal

Pancreatic Adenocarcinoma

NCT04796454 2022-06-01

PAMICC

Phase 2 Withdrawn

Gastrointestinal

Biliary Tract Neoplasms

NCT03101475 2022-05-31

ILOC

Phase 2 Completed

22 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT03102047 2022-04-20

Study of Durvalumab (MEDI4736) After Chemo-Radiation for Microsatellite Stable Stage II-IV Rectal Cancer

Phase 2 Completed

45 enrolled

Gastrointestinal

Rectal Neoplasms

NCT03457896 2022-03-31

Study of Neratinib +Trastuzumab or Neratinib + Cetuximab in Patients With KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer by HER2 Status

Phase 2 Unknown

35 enrolled

Gastrointestinal

Colorectal Neoplasms

Clinical Trials

SLIDE-HCC

PaTcH

NEO: Neoadjuvant Chemotherapy, Excision and Observation for Early Rectal Cancer

Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection

Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread

S1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery

Combining Sodium Valproate With Standard-of-care EGFR (Epidermal Growth Factor Receptor) Monoclonal Antibody Treatment in Patients With Metastatic Colorectal Cancer

Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas

S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis

INNOVATION

Phase II Study of the Combination of Durvalumab (MEDI4736) (PDL1 Inhibitor) and Olaparib (PARP Inhibitor) in Advanced Cholangiocarcinoma After Initial Chemotherapy and Durvalumab (BIL-PPP)

PALEO

EMPIRE

Combined Modality Therapy for Patients With With HIV and Stage I, Stage II, or Stage III Anal Cancer

NEO-IMPACT

ASCEND

Testing Diet Intervention Versus Non-Diet Intervention for Management of Bowel Symptoms in Rectal Cancer Survivors

Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colon Cancer That Cannot Be Removed By Surgery

Paricalcitol Trial: Phase II, Open Label Clinical Trial of Paricalcitol in Combination With Gemcitabine/ Nab-Paclitaxel Therapy in Advanced Pancreatic Cancer

VESTIGE

Durvalumab and Tremelimumab and Best Supportive Care vs Best Supportive Care in Patients With Advanced Colorectal Cancer

Pembrolizumab in Biliary Tract Cancer

Reolysin in Combination With FOLFOX6 and Bevacizumab or FOLFOX6 and Bevacizumab Alone in Metastatic Colorectal Cancer

SB-715992 in Treating Patients With Locally Advanced, Recurrent, or Metastatic Liver Cancer

ALT GIST

Chemotherapy, Surgery, and Radiation Therapy in Treating Patients With Gastric Cancer

Irinotecan and Docetaxel With or Without Cetuximab in Treating Patients With Metastatic Pancreatic Cancer

Chemoembolization in Treating Patients With Primary Liver Cancer or Metastases to the Liver

Bevacizumab and Oxaliplatin Combined With Irinotecan or Leucovorin and Fluorouracil in Treating Patients With Metastatic or Recurrent Colorectal Cancer

Chemotherapy, Radiation Therapy, and Cetuximab Followed by Surgery, Docetaxel, and Cetuximab in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer

Esophagectomy in Treating Patients With High-Grade Dysplasia of the Esophagus or Stage I, Stage II, or Stage III Esophageal Cancer

Cetuximab, Cisplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Anal Cancer

Radiation Therapy and Chemotherapy Before and After Surgery in Treating Patients With Esophageal Cancer

Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy

High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed

Combination Chemotherapy After Surgery in Treating Patients With Cancer of the Esophagus or Stomach

InterAACT

Cryosurgery in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas

Docetaxel Plus Carboplatin in Treating Patients With Advanced Cancer of the Esophagus

Fluorouracil-Uracil and Leucovorin in Treating Elderly Patients With Metastatic Colorectal Cancer

Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer

Study of Durvalumab and Tremelimumab After Radiation for Microsatellite Stable Metastatic Colorectal Cancer Progressing on Chemotherapy

A Single Arm Phase II Study to Evaluate Treatment With Gevokizumab in Patients With Stage II/III Colon Cancer Who Are ctDNA-positive After Curative Surgery and Adjuvant Chemotherapy

S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery

PAMICC

ILOC

Study of Durvalumab (MEDI4736) After Chemo-Radiation for Microsatellite Stable Stage II-IV Rectal Cancer

Study of Neratinib +Trastuzumab or Neratinib + Cetuximab in Patients With KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer by HER2 Status