Clinical Trials

92 trials
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NCT04306939 2026-01-07

GREAT1

University of Pittsburgh

Suspended
120,000 enrolled
Gastrointestinal

Arthritis, Rheumatoid, Celiac Disease, Cholecystitis, Cholelithiasis, Chronic Disease, Crohn Disease, Cystic Fibrosis, Diabetes Mellitus, Fibrosis, Gastritis, Hepatitis, Liver Cirrhosis, Biliary, Multiple Sclerosis, Pancreatic Cyst, Exocrine Pancreatic Insufficiency, Pancreatitis, Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Dyslipidemias, Pancreatitis, Chronic, Renal Insufficiency, Chronic, Chronic Pain, Non-alcoholic Fatty Liver Disease

NCT05400122 2025-11-12

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

Case Comprehensive Cancer Center

Phase 1 Suspended
12 enrolled
GastrointestinalLymphoidMyeloidOther hematologic neoplasmPlasma cell

Esophageal Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasm Metastasis, Rectal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04031469 2025-07-31

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

ProgenaBiome

Suspended
1,000 enrolled
GastrointestinalOtherOther solid neoplasmThoracic

Autism Spectrum Disorder, Bipolar and Related Disorders, Post-Lyme Disease Syndrome, Generalized Anxiety Disorder, Acne Vulgaris, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Anxiety Disorders, Arthritis, Rheumatoid, Autistic Disorder, Bipolar Disorder, Celiac Disease, Colitis, Ulcerative, Colonic Neoplasms, Compulsive Personality Disorder, Constipation, Crohn Disease, Depression, Depressive Disorder, Major, Diabetes Mellitus, Eczema, Epidermolysis Bullosa, Gout, Hypercholesterolemia, Lyme Disease, Mesothelioma, Migraine Disorders, Multiple Sclerosis, Myasthenia Gravis, Neoplasms, Obsessive-Compulsive Disorder, Parkinson Disease, Psoriasis, Colorectal Neoplasms, Fatigue Syndrome, Chronic, Multiple Sclerosis, Chronic Progressive, Multiple Sclerosis, Relapsing-Remitting, Lyme Neuroborreliosis, Irritable Bowel Syndrome

NCT05958199 2025-06-27

A Study of NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7

NextPoint Therapeutics, Inc.

Phase 1 Suspended
131 enrolled
BreastGastrointestinalGenitourinaryGynecologicSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Osteosarcoma, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms