Clinical Trials

125 enrolled

Phase 2 Not yet recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Kidney Neoplasms

NCT07043608 2026-05-01

ZAMBONI

20 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Neoplasm Metastasis

NCT05361720 2026-04-27

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

Phase 2 Recruiting

54 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT06059014 2026-04-24

PRadR

Phase 1/2 Completed

6 enrolled

Clear-cell metastatic renal cell carcinoma

NCT07551349 2026-04-24

DUAL-NK RCC

Phase 1/2 Recruiting

36 enrolled

Phase 2 Not yet recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Kidney Neoplasms

NCT07510334 2026-04-03

VSV-IFNβ-NIS With Ipilimumab and Nivolumab for the Treatment of Advanced or Metastatic Clear Cell Renal Cell Carcinoma

18 enrolled

Phase 2 Enrolling by invitation

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT07488572 2026-03-23

Safety and Efficacy of Yiwoxidan Anti (AK112) Monotherapy in Patients With Metastatic Renal Clear Cell Carcinoma Who Are Intolerant to TKI Treatment: a Prospective, Single Arm, Phase II Clinical Study

60 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT04904302 2026-03-20

Sitravatinib and Nivolumab for the Treatment of Metastatic or Advanced Clear Cell Renal Cell Cancer

15 enrolled

Phase 2 Active not recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT05012371 2026-03-05

Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer

90 enrolled

Phase 1 Active not recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT05122546 2026-03-05

CBM588 in Combination With Nivolumab and Cabozantinib for the Treatment of Advanced or Metastatic Kidney Cancer

31 enrolled

Phase 3 Not yet recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT07383441 2026-02-03

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

718 enrolled

Phase 1/2 Active not recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT05363631 2025-12-10

Seleno-L Methionine (SLM)-Axitinib-Pembrolizumab

55 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT03260504 2025-12-08

Aldesleukin and Pembrolizumab in Treating Patients With Advanced or Metastatic Kidney Cancer

Phase 1 Terminated

6 enrolled 11 charts

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT04370509 2025-11-19

Pembrolizumab With or Without Axitinib for Clear Cell Kidney Cancer in Patients Undergoing Surgery

6 enrolled 11 charts

Phase 2 Not yet recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT07218692 2025-10-20

RP2 and Tivozanib for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy

35 enrolled

Phase 1 Active not recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT04696731 2025-09-25

TRAVERSE

120 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT07179770 2025-09-23

Effects of Belzutifan on 89Zr-DFO-girentuximab PET Uptake in Patients With Renal Cell Carcinoma (RCC)

12 enrolled

Phase 1/2 Active not recruiting

Clear-cell metastatic renal cell carcinoma

NCT06245915 2025-09-22

AB-2100, an Integrated Circuit T Cell Therapy in Patients With Recurrent Clear-cell Renal Cell Carcinoma (ccRCC)

37 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Kidney Neoplasms, Recurrence

NCT04510597 2025-09-09

PROBE

Phase 3 Recruiting

364 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT06866262 2025-09-09

Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial

Phase 1/2 Recruiting

55 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT06361810 2025-08-19

PSMA Therapy and Immunotherapy in Kidney Cancer

Phase 1/2 Withdrawn

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Kidney Neoplasms

NCT06942104 2025-07-18

Imaging of Solid Tumors Using 18F-TRX

56 enrolled

CNSGenitourinary

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Glioma, Neoplasm Metastasis, Prostatic Neoplasms

NCT01693822 2024-11-21

A-PREDICT

65 enrolled 15 charts

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT02978404 2024-06-28

Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases

CNSDermatologicGenitourinaryThoracic

26 enrolled

Clear-cell metastatic renal cell carcinoma, Brain Neoplasms, Melanoma, Small Cell Lung Carcinoma

NCT06399419 2024-05-30

CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer

28 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT05567588 2024-02-01

Pembrolizumab Plus Radiotherapy for Advanced Renal Cancer

Phase 2 Unknown

66 enrolled

Clear-cell metastatic renal cell carcinoma

NCT05879471 2023-07-24

68Ga-NY104 PET/CT in Patients With Metastatic Clear Cell Renal Cell Carcinoma

Phase 2 Unknown

39 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT03679767 2023-07-21

A Study of INCMGA00012 in Participants With Selected Solid Tumors (POD1UM-203)

DermatologicGenitourinaryThoracic

121 enrolled 25 charts

Clear-cell metastatic renal cell carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma

NCT05753839 2023-06-22

SEVURO-CN

Phase NA Recruiting

40 enrolled

Phase 1 Not yet recruiting

Clear-cell metastatic renal cell carcinoma, Kidney Neoplasms, Neoplasms, Multiple Primary

NCT05698238 2023-03-15

CAMP1

50 enrolled

BreastGenitourinaryHead & NeckOther solid neoplasmThoracic

Clear-cell metastatic renal cell carcinoma, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Triple Negative Breast Neoplasms

NCT02917772 2022-10-06

TITAN-RCC

200 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT03334409 2022-03-31

Pazopanib Hydrochloride With or Without Ascorbic Acid in Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed by Surgery

5 enrolled 16 charts

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT01472081 2021-12-02

Nivolumab (BMS-936558; MDX-1106) in Combination With Sunitinib, Pazopanib, or Ipilimumab in Subjects With Metastatic Renal Cell Carcinoma (RCC) (CheckMate 016)

Phase 1 Completed

194 enrolled 18 charts

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT01896271 2021-08-23

High Dose IL-2 and Stereotactic Ablative Body Radiation Therapy for Metastatic Renal Cancer

30 enrolled 12 charts

Clear-cell metastatic renal cell carcinoma, Kidney Neoplasms, Neoplasm Metastasis

NCT02960906 2021-04-26

BIONIKK

200 enrolled

Clear-cell metastatic renal cell carcinoma

NCT02019576 2021-03-23

Stereotactic Radiotherapy for Metastatic Kidney Cancer Being Treated With Sunitinib

38 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT01391130 2019-07-23

A Study of LY2510924 and Sunitinib in Patients With Metastatic Renal Cell Carcinoma

110 enrolled 14 charts

Clear-cell metastatic renal cell carcinoma, Neoplasm Metastasis, Neoplasms

NCT02386111 2018-07-26

A Study of Varlilumab (Anti-CD27) and Sunitinib in Patients With Metastatic Clear Cell Renal Cell Carcinoma

Phase 1 Terminated

17 enrolled

BreastDermatologicGenitourinaryHead & NeckThoracic

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Kidney Diseases, Kidney Neoplasms, Neoplasms, Neoplasms by Histologic Type, Urogenital Neoplasms, Urologic Diseases, Urologic Neoplasms

NCT02543645 2018-04-30

A Study of Varlilumab and Atezolizumab in Patients With Advanced Cancer

Phase 1 Terminated

18 enrolled

Clear-cell metastatic renal cell carcinoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Kidney Diseases, Kidney Neoplasms, Melanoma, Neoplasms, Neoplasms by Histologic Type, Urogenital Neoplasms, Urologic Diseases, Urologic Neoplasms, Triple Negative Breast Neoplasms

NCT01499121 2018-03-06

Study of Efficacy and Safety of Sunitinib Given on an Individualized Schedule

117 enrolled

Clear-cell metastatic renal cell carcinoma

NCT01521715 2017-08-23

FLIPPER

Phase 4 Completed

44 enrolled