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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Other hematologic neoplasm 1Lymphoid 1Gynecologic 1Genitourinary 1Dermatologic 1Breast 1

Conditions

Prostatic Neoplasms 31Urinary Bladder Neoplasms 4Carcinoma, Renal Cell 3Neoplasms 2Metabolic Syndrome 2Lung Neoplasms 2Kidney Neoplasms 2Endometrial Neoplasms 2Breast Neoplasms 2Weight Gain 1Waldenstrom Macroglobulinemia 1Urothelial Cancer 1Small Cell Lung Carcinoma 1Sezary Syndrome 1Rectal Neoplasms 1Prostate Cancer Recurrent 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pancreatic Neoplasms 1Non-Muscle Invasive Bladder Neoplasms 1Mycosis Fungoides 1Melanoma 1Lymphoma, T-Cell, Cutaneous 1Lymphoma, Non-Hodgkin 1Lymphoma, Mantle-Cell 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Large-Cell, Anaplastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lymphoma, Extranodal NK-T-Cell 1

Interventions

Cyclophosphamide 8fludarabine phosphate 7Peripheral Blood Stem Cell Transplantation 7Mycophenolic Acid 6Flow Cytometry 6Whole-Body Irradiation 5Therapeutics 5Cyclosporine 5Radiotherapy 4Polymerase Chain Reaction 4Busulfan 4Antilymphocyte Serum 4Vorinostat 3Tacrolimus 3Nivolumab 3Methylprednisolone 3Methotrexate 3Immunoenzyme Techniques 3Carboplatin 3Amplified Fragment Length Polymorphism Analysis 3Alemtuzumab 3thymoglobulin 2pembrolizumab 2liposomal amphotericin B 2durvalumab 2Thiotepa 2Sunitinib 2Specimen Handling 2Psychiatric Rehabilitation 2Prednisone 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Hodgkin Disease × Metformin × Genitourinary × Clear all
NCT00659568 2013-05-30

Metformin and Temsirolimus in Treating Patients With Metastatic or Unresectable Solid Tumor or Lymphoma

National Cancer Institute (NCI)

Phase 1 Completed
28 enrolled
BreastDermatologicGenitourinaryGynecologicLymphoidOther hematologic neoplasmThoracic

Breast Neoplasms, Burkitt Lymphoma, Carcinoma, Renal Cell, Hodgkin Disease, Immunoblastic Lymphadenopathy, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Endometrial Neoplasms, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Small Cell Lung Carcinoma

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