Clinical Trials

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

71 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Melanoma, Mesothelioma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT06321640 2024-03-20

POSITive

BreastDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

265 enrolled

Breast Neoplasms, Carcinoma, Transitional Cell, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Colorectal Neoplasms

NCT04544748 2024-03-06

A Phase 1 Study of GNR-051 in Subjects With Advanced Malignancies

48 enrolled

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Histologic Type, Urologic Neoplasms

NCT04670445 2023-10-23

UPLIFT

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

210 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Melanoma, Mesothelioma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms

NCT05708950 2023-07-13

A Clinical Trial of KVA12123 Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)

Phase 1/2 Unknown

314 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Breast Neoplasms, Carcinoma, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Uterine Neoplasms

NCT05223218 2023-07-03

Investigating the Diagnostic Potential of Tear Proteins in Cancer - A Pilot Study

BreastDermatologicGastrointestinalGenitourinaryGynecologic

500 enrolled

Breast Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT04146064 2023-06-05

Breathomics as Predictive Biomarker for Checkpoint Inhibitor Response

DermatologicGenitourinaryHead & Neck

425 enrolled

Carcinoma, Transitional Cell, Head and Neck Neoplasms, Kidney Neoplasms, Melanoma

NCT04631731 2023-06-01

ICEMELT

Phase 1/2 Unknown

200 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicOther solid neoplasmThoracic

Diabetes Mellitus, Insulin-Dependent, 12, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Stomach Neoplasms, Endometrial Neoplasms

NCT05823246 2023-05-26

Safety and Efficacy Study of QLF31907 in Advanced Melanoma and Urothelial Carcinoma

66 enrolled

Carcinoma, Transitional Cell, Melanoma

NCT05429866 2023-03-08

Immunological Variables Associated to ICI Toxicity in Cancer Patients

BreastDermatologicGastrointestinalGenitourinaryHead & NeckOther solid neoplasmThoracic

441 enrolled

Mesothelioma, Malignant, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Melanoma, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma

NCT04107168 2023-02-16

Microbiome Immunotherapy Toxicity and Response Evaluation

1,800 enrolled

Kidney Neoplasms, Lung Neoplasms, Melanoma

NCT04913025 2022-09-21

REFINE

160 enrolled

Carcinoma, Renal Cell, Melanoma

NCT03634982 2022-09-01

Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

133 enrolled

Urinary Bladder Neoplasms, Bronchial Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Melanoma, Neoplasms, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Noonan Syndrome, Ovarian Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Skin Neoplasms, Thoracic Neoplasms, Uterine Neoplasms, Neoplasms, Squamous Cell

NCT03934827 2022-08-11

MICROBIOME

BreastDermatologicGenitourinaryGynecologicHead & NeckThoracic

120 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Urethral Neoplasms, Uterine Neoplasms

NCT05426317 2022-06-22

Onco-PDL1s/B2M

100 enrolled

Carcinoma, Non-Small-Cell Lung, Kidney Neoplasms, Melanoma

NCT05235607 2022-02-11

Personalized Immune Cell Therapy Targeting Neoantigen of Malignant Solid Tumors

DermatologicGastrointestinalGenitourinary

60 enrolled

Urinary Bladder Neoplasms, Carcinoma, Melanoma, Colorectal Neoplasms

NCT05230186 2022-02-09

A Tissue Collection Study in Patients Who Respond to Immune Checkpoint Inhibitors to Identify Targets of Tumor-Reactive T Cells.

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

200 enrolled

Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Colonic Neoplasms, Lung Neoplasms, Melanoma, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05180851 2022-02-01

YSCH-01

Phase EARLY_PHASE1 Unknown

28 enrolled

BreastDermatologicGenitourinaryGynecologicHead & NeckThoracic

Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Ovarian Neoplasms, Virus Diseases

NCT04773951 2021-08-24

A Phase I Study to Evaluate the Safety, Tolerability and Pharmacokinetics of JS004 in Advanced Solid Tumors

156 enrolled

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma

NCT04177056 2021-08-02

SOLAR-P

BreastDermatologicGenitourinary

40 enrolled

Breast Neoplasms, Carcinoma, Renal Cell, Melanoma, Prostatic Neoplasms

NCT04628806 2021-05-14

HSP70CTC

BreastDermatologicGastrointestinalGenitourinarySarcoma

120 enrolled

Breast Neoplasms, Carcinoma, Squamous Cell, Melanoma, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma

NCT04142931 2021-03-24

Sequentional Immuno Apheresis Plasma Volume Escalation Cohort Study of Reduction of Soluble Tumor Necrosis Factor Receptors 1 and 2 (sTNFR1/2) With or Without Nivolumab in Patients With Inoperable or Metastatic Solid Tumors

BreastDermatologicGenitourinaryThoracic

30 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Triple Negative Breast Neoplasms

NCT03896958 2020-12-04

PIONEER

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

1,000 enrolled

Adenocarcinoma of Lung, Adrenal Gland Neoplasms, Anus Neoplasms, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Neoplasms, Unknown Primary, Neurologic Manifestations, Oligodendroglioma, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Uterine Neoplasms, Vulvar Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Thyroid Carcinoma, Anaplastic

NCT03086174 2020-09-30

Tolerability and Pharmacokinetics of Toripalimab in Combination With Axitinib in Patients With Kidney Cancer and Melanoma

24 enrolled

Kidney Neoplasms, Melanoma

NCT03544723 2020-06-09

Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.

BreastDermatologicGastrointestinalGenitourinaryGynecologicLymphoidThoracic

40 enrolled

Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Hodgkin Disease, Liver Neoplasms, Lymphoma, Melanoma, Stomach Neoplasms, Carcinoma, Merkel Cell, Neoplasms, Squamous Cell, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04268368 2020-02-17

ICI-DISCOVER

200 enrolled

CNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidOther hematologic neoplasmOther solid neoplasmPlasma cellSarcomaThoracic

Carcinoma, Renal Cell, Lung Neoplasms, Melanoma, Neoplasms

NCT03638206 2019-12-11

Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies

Phase 1/2 Unknown

73 enrolled

Burkitt Lymphoma, Carcinoma, Renal Cell, Esophageal Neoplasms, Glioma, Carcinoma, Hepatocellular, Leukemia, Myeloid, Lung Neoplasms, Lymphoma, Melanoma, Mesothelioma, Multiple Myeloma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Sarcoma, Synovial, Colorectal Neoplasms

NCT02861209 2019-04-16

CONTACT

BreastDermatologicGastrointestinalGenitourinaryThoracic

228 enrolled

Breast Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms, Colorectal Neoplasms

NCT03517332 2018-11-20

Circulating Tumor DNA Exposure in Peripheral Blood

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

10,000 enrolled

Adrenal Cortex Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT03050047 2018-08-31

A Multicenter Open-Label Single-Arm Multi-Cohort Phase I Study of BCD-100 in Patients With Advanced Solid Tumors

15 enrolled

Carcinoma, Renal Cell, Lung Neoplasms, Melanoma

NCT03464032 2018-03-13

A Study of BCD-135 in Patients With Advanced Solid Tumors

30 enrolled

Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Melanoma

NCT03098160 2017-10-30

Immunotherapy Study of Evofosfamide in Combination With Ipilimumab

DermatologicGastrointestinalGenitourinaryHead & Neck

69 enrolled

Squamous Cell Carcinoma of Head and Neck, Hypoxia, Melanoma, Pancreatic Neoplasms, Prostatic Neoplasms

NCT02457650 2016-08-03

T Cell Receptor-transduced T Cells Targeting NY-ESO-1 for Treatment of Patients With NY-ESO-1- Expressing Malignancies

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicPlasma cellSarcomaThoracic

36 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Melanoma, Multiple Myeloma, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Synovial

NCT00757614 2013-08-26

Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom

CNSDermatologicGastrointestinalGenitourinaryLymphoidOther hematologic neoplasm

14,000 enrolled

Uveal Melanoma, Astrocytoma, Urinary Bladder Neoplasms, Brain Neoplasms, Carcinoma, Renal Cell, Craniopharyngioma, Esophageal Neoplasms, Hodgkin Disease, Kidney Neoplasms, Lymphoma, Lymphoma, Non-Hodgkin, Melanoma, Meningeal Neoplasms, Neoplasms, Germ Cell and Embryonal, Pancreatic Neoplasms, Pinealoma, Lymphoma, T-Cell, Cutaneous, Lymphoma, AIDS-Related, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Nephroma, Mesoblastic, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Intraocular Lymphoma

NCT00610389 2010-05-10

Phase II Study With Immunotherapy With Dendritic Cells and Tumor Infiltrating Lymphocytes in Solid Tumors

DermatologicGastrointestinalGenitourinary

27 enrolled

Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Melanoma

NCT00294476 2006-10-12

IVIG in the Treatment of Metastatic Cancers of the Prostate, Colon and Melanoma