Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Terminated 1Active not recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2Head & Neck 2Gynecologic 2Genitourinary 2CNS 2Thoracic 1Other solid neoplasm 1Lymphoid 1Gastrointestinal 1Endocrine 1Dermatologic 1

Conditions

Carcinoma, Renal Cell 132Carcinoma, Transitional Cell 91Carcinoma, Non-Small-Cell Lung 84Urinary Bladder Neoplasms 81Melanoma 75Squamous Cell Carcinoma of Head and Neck 50Prostatic Neoplasms 49Colorectal Neoplasms 41Ovarian Neoplasms 36Stomach Neoplasms 35Triple Negative Breast Neoplasms 33Neoplasm Metastasis 32Uterine Cervical Neoplasms 31Neoplasms 28Kidney Neoplasms 27Breast Neoplasms 27Parkinson Disease 4, Autosomal Dominant Lewy Body 26Lung Neoplasms 26Pancreatic Neoplasms 23Carcinoma, Hepatocellular 23Esophageal Neoplasms 21Head and Neck Neoplasms 20Endometrial Neoplasms 18Small Cell Lung Carcinoma 16Carcinoma, Merkel Cell 11Mesothelioma 9Cholangiocarcinoma 9Ureteral Neoplasms 8Sarcoma 8Carcinoma, Ovarian Epithelial 8

Interventions

Cyclophosphamide 4Etoposide 3pembrolizumab 2fludarabine 2etoposide phosphate 2Sirolimus 2Paclitaxel 2Mesna 2Melphalan 2Granulocyte Colony-Stimulating Factor 2Gemcitabine 2Cisplatin 2Carboplatin 2Busulfan 2Brentuximab Vedotin 2tremelimumab 1ripretinib 1pegylated granulocyte colony-stimulating factor 1pegfilgrastim 1pazopanib 1guadecitabine 1fosaprepitant 1fludarabine phosphate 1durvalumab 1bintrafusp alfa protein, human 1avelumab 1Vorinostat 1Ursodeoxycholic Acid 1Topotecan 1Thiotepa 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Neoplasms, Germ Cell and Embryonal × pembrolizumab × Genitourinary × Clear all
NCT04483778 2026-04-28

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Seattle Children's Hospital

Phase 1 Active not recruiting
68 enrolled
CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT02499952 2022-07-11

Pembrolizumab in Subjects With Incurable Platinum-Refractory Germ Cell Tumors

Hoosier Cancer Research Network

Phase 2 Terminated
12 enrolled 14 charts
GenitourinaryGynecologic

Nonseminomatous germ cell tumor, Genital Neoplasms, Female, Genital Neoplasms, Male, Mediastinal Neoplasms, Neoplasms, Germ Cell and Embryonal, Ovarian Neoplasms, Testicular Neoplasms

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