Clinical Trials Browser

OTHER × Neoplasms, Germ Cell and Embryonal × Genitourinary × Clear all

NCT04308330 2026-04-15

NYMC195

Phase 1 Recruiting

CNSGastrointestinalGenitourinarySarcoma

Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Hepatoblastoma

NCT04897321 2026-04-15

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

Phase 1 Recruiting

CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT02433197 2026-04-08

EFICATEST

Phase NA Completed

Motor Activity, Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT01625351 2026-02-06

A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas

Phase 1 Completed

CNSDermatologicGastrointestinalGenitourinaryLymphoidSarcoma

Carcinoma, Renal Cell, Digestive System Neoplasms, Carcinoma, Hepatocellular, Lymphoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Adenocarcinoma, Clear Cell, Rhabdoid Tumor

NCT02099734 2026-02-04

Germ Cell Tumor and Testicular Tumor DNA Registry

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT06828185 2026-02-04

PRESERVE

Phase NA Recruiting

Neoplasms, Germ Cell and Embryonal, Pain, Postoperative, Testicular Neoplasms

NCT06866964 2026-02-02

ASPIRE

Phase 2 Recruiting

Classical hematologyGenitourinary

Neoplasms, Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms, Venous Thromboembolism

NCT03618381 2025-11-20

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Phase 1 Active not recruiting

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT04483778 2025-11-20

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Phase 1 Active not recruiting

CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT02162732 2025-11-03

Molecular-Guided Therapy for Childhood Cancer

Phase NA Completed

186 enrolled 12 charts

CNSGastrointestinalGenitourinarySarcoma

Carcinoma, Renal Cell, Craniopharyngioma, Ependymoma, Glioma, Carcinoma, Hepatocellular, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Choroid Plexus Neoplasms, Sarcoma, Clear Cell, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT03426865 2025-08-11

TESTPET

Testicular Germ Cell Tumor, Neoplasms, Germ Cell and Embryonal, Teratoma, Testicular Diseases, Testicular Neoplasms, Endodermal Sinus Tumor

NCT02076906 2025-01-01

MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors

Phase 1 Completed

CNSGastrointestinalGenitourinarySarcoma

Carcinoma, Hepatocellular, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Desmoid Tumors

NCT04791228 2025-01-01

A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors

Phase 2 Withdrawn

GastrointestinalGenitourinarySarcoma

Carcinoma, Carcinoma, Hepatocellular, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Recurrence, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing

NCT03507491 2024-10-04

Nab-paclitaxel in Combination with Gemcitabine for Pediatric Relapsed and Refractory Solid Tumors

Phase 1 Completed

CNSGastrointestinalGenitourinarySarcoma

Neoplasms, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma

NCT02624388 2024-05-06

UVA-Gen001

Phase 2 Terminated

4 enrolled 16 charts

CNSGenitourinaryLymphoidSarcoma

Brain Neoplasms, Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Medulloblastoma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Neuroectodermal Tumors, Primitive

NCT06309732 2024-03-13

GAMEC-II

Phase 2 Completed

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT01505569 2024-02-26

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

Phase NA Completed

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Brain Neoplasms, Carcinoma, Renal Cell, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Rhabdoid Tumor

NCT06133699 2024-01-03

PITERLAND

Phase NA Unknown

Testicular Germ Cell Tumor, Neoplasms, Germ Cell and Embryonal

NCT02536183 2023-08-29

A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors

Phase 1 Terminated

CNSGastrointestinalGenitourinarySarcoma

Carcinoma, Hepatocellular, Neoplasms, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT02499952 2022-07-11

Pembrolizumab in Subjects With Incurable Platinum-Refractory Germ Cell Tumors

Phase 2 Terminated

12 enrolled 14 charts

GenitourinaryGynecologic

Nonseminomatous germ cell tumor, Genital Neoplasms, Female, Genital Neoplasms, Male, Mediastinal Neoplasms, Neoplasms, Germ Cell and Embryonal, Ovarian Neoplasms, Testicular Neoplasms

NCT05179850 2022-01-20

Computer Aided Diagnostic Tool on Computed Tomography Images for Diagnosis of Retroperitoneal Tumor in Children

CNSGenitourinaryLymphoidSarcoma

Lymphoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Sarcoma, Teratoma

NCT01743482 2021-05-14

Pazotest-01

Phase 2 Completed

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT03081923 2021-05-14

APACHE

Phase 2 Terminated

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT02429466 2020-09-23

Study of the Hypomethylating Drug Guadecitabine (SGI-110) Plus Cisplatin in Relapsed Refractory Germ Cell Tumors

Phase 1 Completed

Testicular Germ Cell Tumor, Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT01331135 2020-05-29

Aflac ST0901

Phase 1 Completed

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Astrocytoma, Carcinoma, Renal Cell, Ependymoma, Glioma, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Recurrence, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Rhabdoid Tumor

NCT02390843 2020-04-03

AflacST1402

Phase 1 Completed

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Renal Cell, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Rhabdoid Tumor

NCT02689219 2019-12-10

Brentuximab Vedotin in Relapsed/Refractory Germ Cell Tumors

Phase 2 Terminated

18 enrolled 13 charts

Nonseminomatous germ cell tumor, Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms, Carcinoma, Embryonal

NCT01851200 2018-02-07

Brentuximab Vedotin (SGN-35) as Salvage Treatment for CD30-positive Germ Cell Tumors

Phase 2 Completed

Neoplasm Metastasis, Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms, Carcinoma, Embryonal

NCT00183820 2017-07-07

Study of Gemcitabine, Oxaliplatin, and Paclitaxel in Patients With Refractory Germ Cell Carcinoma

Phase 2 Completed

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT01736917 2016-05-25

Fosaprepitant + 5HT3 Receptor Antagonists + Dexamethasone in Germ Cell Tumors

Phase 2 Completed

65 enrolled 14 charts

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms, Vomiting

NCT01242631 2015-02-25

RADIT

Phase 2 Completed

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT02161692 2014-06-12

Conventional Dose Versus High Dose Sequential Chemotherapy for Poor Prognosis Germ Cell Tumors

Phase 2 Completed

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT00179816 2010-10-11

Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors

Phase 1/2 Unknown

GastrointestinalGenitourinaryLymphoidSarcoma

Hodgkin Disease, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Sarcoma, Sarcoma, Ewing, Hepatoblastoma

NCT00772694 2008-10-24

GCT

Phase 2 Unknown

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms