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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Carcinoma, Renal Cell 40Kidney Neoplasms 30Melanoma 25Prostatic Neoplasms 24Breast Neoplasms 18Wilms Tumor 16Neoplasm Metastasis 16Ovarian Neoplasms 14Carcinoma, Non-Small-Cell Lung 12Testicular Neoplasms 11Multiple Myeloma 11Uterine Cervical Neoplasms 10Sarcoma 9Pancreatic Neoplasms 9Neuroblastoma 9Testicular Germ Cell Tumor 8Lymphoma, Follicular 8Lymphoma 8Lung Neoplasms 8Hodgkin Disease 8Carcinoma, Hepatocellular 8Triple Negative Breast Neoplasms 7Neoplasms, Plasma Cell 7Neoplasms 7Lymphoma, Non-Hodgkin 7Lymphoma, Mantle-Cell 7Lymphoma, Large-Cell, Immunoblastic 7Lymphoma, Large B-Cell, Diffuse 7Leukemia, Myeloid, Acute 7Leukemia, Lymphocytic, Chronic, B-Cell 7

Interventions

Nivolumab 2Ifosfamide 2Filgrastim 2Doxorubicin 2selinexor 1pembrolizumab 1lorvotuzumab mertansine 1fludarabine phosphate 1fludarabine 1Specimen Handling 1Radiotherapy 1Mesna 1Magnetic Resonance Spectroscopy 1Ipilimumab 1Imatinib Mesylate 1Cyclophosphamide 1Chemotherapy, Adjuvant 1CTLA-4 Antigen 1Ado-Trastuzumab Emtansine 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Neurofibrosarcoma × Cyclophosphamide × Genitourinary × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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