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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 8Thoracic 1Lymphoid 1Gynecologic 1Genitourinary 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Prostatic Neoplasms 17Urinary Bladder Neoplasms 10Kidney Neoplasms 6Pancreatic Neoplasms 4Neoplasms 4Head and Neck Neoplasms 4Ovarian Neoplasms 3Neoplasm Metastasis 3Melanoma 3Lung Neoplasms 3Colorectal Neoplasms 3Carcinoma, Renal Cell 3Breast Neoplasms 3Wilms Tumor 2Uterine Cervical Neoplasms 2Testicular Neoplasms 2Stomach Neoplasms 2Skin Neoplasms 2Sarcoma 2Muscle-invasive Bladder Cancer 2Multiple Myeloma 2Lymphoma, Non-Hodgkin 2Liver Neoplasms 2Laryngeal Neoplasms 2Fallopian Tube Neoplasms 2Esophageal Neoplasms 2Colonic Neoplasms 2Cholangiocarcinoma 2Central Nervous System Neoplasms 2Carcinoma, Transitional Cell 2

Interventions

pembrolizumab 5fludarabine 4aldesleukin 4Cyclophosphamide 4fludarabine phosphate 2Taxes 2Polymerase Chain Reaction 2Gene Expression Profiling 2Counseling 2Bupropion 2Adoptive Transfer 2motexafin gadolinium 1entinostat 1bintrafusp alfa protein, human 1Zinc Oxide 1Vorinostat 1Varenicline 1Tobacco Use Cessation Devices 1Ritonavir 1Radiotherapy 1Psychiatric Rehabilitation 1Pemetrexed 1Paclitaxel 1Nivolumab 1Nicotine Replacement Therapy 1Nicotine 1Interleukin-2 1Indinavir 1Immunohistochemistry 1Fluorodeoxyglucose F18 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Oropharyngeal Neoplasms × Drug Therapy × Genitourinary × Clear all
NCT03329950 2024-03-28

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

Celldex Therapeutics

Phase 1 Completed
132 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Mouth Neoplasms, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Cholangiocarcinoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Hyper-IgM Immunodeficiency Syndrome

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