Clinical Trials Browser

Adenocarcinoma, Prostatic Neoplasms

NCT07567027 2026-05-05

Improving Cryoablation Efficacy With BARRigel Rectal Spacing (ICE-BARR)

Phase NA Not yet recruiting

20 enrolled

Genitourinary

Disease, Prostatic Neoplasms

NCT04693377 2026-04-15

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

Phase NA Recruiting

40 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasm Metastasis, Prostatic Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT04701918 2026-01-22

Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma

Phase 2 Completed

9 enrolled

Genitourinary

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT05302921 2025-01-01

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

Phase 2 Completed

5 enrolled

CNSDermatologicGastrointestinalGenitourinarySarcoma

Carcinoma, Hepatocellular, Melanoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma

NCT06178354 2024-12-16

Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer

Phase NA Recruiting

100 enrolled

Genitourinary

Prostatic Neoplasms

NCT06491056 2024-07-08

ProAMFocal

Recruiting

500 enrolled

Genitourinary

Prostatic Neoplasms

NCT01117779 2024-01-19

TRACE

Terminated

246 enrolled 18 charts

Genitourinary

Carcinoma, Renal Cell, Kidney Neoplasms

NCT03390413 2023-06-01

ROAST

Phase NA Withdrawn

Genitourinary

Kidney Neoplasms

NCT02626130 2022-07-07

Tremelimumab With or Without Cryoablation in Treating Patients With Metastatic Kidney Cancer

Phase EARLY_PHASE1 Completed

29 enrolled

Genitourinary

Carcinoma, Renal Cell

NCT02489357 2021-11-12

Pembrolizumab and Cryosurgery in Treating Patients With Newly Diagnosed, Oligo-metastatic Prostate Cancer

Phase NA Completed

12 enrolled 5 charts

Genitourinary

Prostatic Neoplasms

NCT04506671 2021-07-28

Percutaneous Cryoablation Versus Partial Nephrectomy for T1b Renal Tumor

Phase NA Unknown

142 enrolled

Genitourinary

Carcinoma, Renal Cell, Kidney Neoplasms

NCT03189186 2021-04-05

Phase-I Trial of Pembrolizumab and Percutaneous Cryoablation Combination Followed by Nephron-Sparing Surgery or Cytoreductive Nephrectomy in Locally Advanced and Metastatic Renal Cell Carcinomas

Phase 1 Withdrawn

Genitourinary

Carcinoma, Renal Cell, Kidney Neoplasms

NCT00514215 2020-03-05

Cryotherapy and GM-CSF in Treating Patients With Lung Metastases or Primary Lung Cancer

Phase 2 Completed

8 enrolled 5 charts

GenitourinaryThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Kidney Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT01065441 2020-01-22

Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer

Phase 1/2 Completed

9 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicSarcomaThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Melanoma, Ovarian Neoplasms, Prostatic Neoplasms, Sarcoma, Colorectal Neoplasms

NCT02843607 2019-09-12

Combination of Cryosurgery and NK Immunotherapy for Advanced Kidney Cancer

Phase 1/2 Completed

30 enrolled

Genitourinary

Carcinoma, Renal Cell, Kidney Neoplasms

NCT00499733 2019-01-18

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

Phase EARLY_PHASE1 Terminated

19 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Chondrosarcoma, Colonic Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Neoplasms, Unknown Primary, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Osteosarcoma, Tongue Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Esthesioneuroblastoma, Olfactory, Breast Neoplasms, Male, Small Cell Lung Carcinoma, Intraocular Lymphoma

NCT00540969 2018-11-21

Cryoablation or External-Beam Radiation Therapy in Treating Patients With Painful Bone Metastases

Phase 3 Terminated

3 enrolled 1 chart

DermatologicGenitourinary

Carcinoma, Renal Cell, Kidney Neoplasms, Melanoma, Neoplasm Metastasis, Pain

NCT00877682 2018-01-31

Prostate Conformal Cryotherapy

Phase NA Completed

48 enrolled

Genitourinary

Prostatic Neoplasms

NCT02760953 2017-10-19

TURBt With Adjuvant Cryoablation to Treat Bladder Cancer

Phase NA Unknown

150 enrolled

Genitourinary

Urinary Bladder Neoplasms

NCT02615223 2017-06-12

CRYO-PCA-IV

Phase NA Unknown

120 enrolled

Genitourinary

Prostatic Neoplasms

NCT00922948 2016-07-27

Cryoablation Versus Radiofrequency Ablation for Small Renal Masses

Phase 2 Withdrawn

Genitourinary

Kidney Neoplasms

NCT00824928 2015-05-27

SCORE

Terminated

60 enrolled

Genitourinary

Prostatic Neoplasms

NCT00489060 2008-07-17

A Randomized Trial of External Beam Radiotherapy Versus Cryoablation in Patients With Localized Prostate Cancer

Phase 3 Completed

244 enrolled

Genitourinary

Prostatic Neoplasms

Clinical Trials

TA-P-OLIM

Improving Cryoablation Efficacy With BARRigel Rectal Spacing (ICE-BARR)

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer

ProAMFocal

TRACE

ROAST

Tremelimumab With or Without Cryoablation in Treating Patients With Metastatic Kidney Cancer

Pembrolizumab and Cryosurgery in Treating Patients With Newly Diagnosed, Oligo-metastatic Prostate Cancer

Percutaneous Cryoablation Versus Partial Nephrectomy for T1b Renal Tumor

Phase-I Trial of Pembrolizumab and Percutaneous Cryoablation Combination Followed by Nephron-Sparing Surgery or Cytoreductive Nephrectomy in Locally Advanced and Metastatic Renal Cell Carcinomas

Cryotherapy and GM-CSF in Treating Patients With Lung Metastases or Primary Lung Cancer

Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer

Combination of Cryosurgery and NK Immunotherapy for Advanced Kidney Cancer

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

Cryoablation or External-Beam Radiation Therapy in Treating Patients With Painful Bone Metastases

Prostate Conformal Cryotherapy

TURBt With Adjuvant Cryoablation to Treat Bladder Cancer

CRYO-PCA-IV

Cryoablation Versus Radiofrequency Ablation for Small Renal Masses

SCORE

A Randomized Trial of External Beam Radiotherapy Versus Cryoablation in Patients With Localized Prostate Cancer