Clinical Trials

Urinary Bladder Neoplasms

NCT03798626 2026-04-01

Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorectal, Gastroesophageal, and Renal Cancers

GastrointestinalGenitourinary

167 enrolled

Carcinoma, Renal Cell, Colorectal Neoplasms

NCT05891171 2026-03-31

ARC-25

Phase 1 Active not recruiting

40 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Triple Negative Breast Neoplasms

NCT04216290 2025-11-12

A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, INSPIRE Trial

Phase 2 Active not recruiting

95 enrolled

Phase 2 Active not recruiting

Urinary Bladder Neoplasms

NCT00082706 2025-09-09

Fluorouracil, Leucovorin, Gemcitabine, and Cisplatin in Treating Patients With Metastatic or Unresectable Adenocarcinoma of the Urothelium or Urachal Remnant

46 enrolled

Urachal cancer, Urinary Bladder Neoplasms, Urethral Neoplasms

NCT05007106 2025-08-14

KEYVIBE-005

BreastGastrointestinalGenitourinaryGynecologicHead & Neck

613 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Ovarian Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT03872947 2025-08-03

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Phase 1 Active not recruiting

138 enrolled

DermatologicGastrointestinalGenitourinaryGynecologic

Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Melanoma, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Phase 1 Terminated

221 enrolled

BreastDermatologicGenitourinaryGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT05704985 2025-05-29

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

Phase 1 Active not recruiting

39 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Kidney Neoplasms, Neoplasms, Pancreatic Neoplasms, Skin Neoplasms, Colorectal Neoplasms

NCT03197571 2025-02-21

QUILT-3.048: NANT Urothelial Cancer Vaccine: Combination Immunotherapy in Subjects With Urothelial Cancer Who Have Progressed on or After Chemotherapy and PD-1/PD-L1 Therapy

Phase 1/2 Withdrawn

Phase 2 Active not recruiting

Carcinoma, Transitional Cell

NCT02710734 2024-12-24

Risk Enabled Therapy After Initiating Neoadjuvant Chemotherapy for Bladder Cancer (RETAIN)

78 enrolled

Phase 3 Active not recruiting

Urothelial Carcinoma of the Bladder

NCT04241185 2024-11-25

MK-3475-992

520 enrolled

Urinary Bladder Neoplasms

NCT00981656 2024-09-19

Radiation Therapy and Chemotherapy in Treating Patients With Stage I Bladder Cancer

37 enrolled 19 charts

BreastClassical hematologyGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmPlasma cell

Urinary Bladder Neoplasms

NCT03878524 2024-03-04

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Phase 1 Terminated

2 enrolled

Anemia, Blast Crisis, Breast Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Thrombocytosis, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT05733000 2023-03-10

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

Phase 2 Recruiting

94 enrolled

GastrointestinalGenitourinaryGynecologicThoracic

Adenocarcinoma of Lung, Carcinoma, Transitional Cell, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT03617913 2023-01-06

Avelumab in Combination With Fluorouracil and Mitomycin or Cisplatin and Radiation Therapy in Treating Participants With Muscle-Invasive Bladder Cancer

2 enrolled 8 charts

Urinary Bladder Neoplasms, Ureteral Neoplasms, Urethral Neoplasms

NCT00777491 2022-06-15

Chemotherapy and Radiation Therapy in Treating Patients With Stage II or Stage III Bladder Cancer That Was Removed by Surgery

70 enrolled 18 charts

Urinary Bladder Neoplasms

NCT00006111 2021-02-21

Surgery Plus Combination Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Urinary Tract

53 enrolled

Urinary Bladder Neoplasms, Urethral Neoplasms

NCT00055601 2018-06-15

Combination Chemotherapy and Radiation Therapy With/Without Surgery In Patients With Stage II/III Bladder Cancer

97 enrolled 8 charts

Urinary Bladder Neoplasms

NCT01658813 2018-03-21

5-Fluorouracil Followed by Interferon-alfa-2b in Previously-treated Metastatic Gastrointestinal, Kidney, or Lung Cancer

GastrointestinalGenitourinaryThoracic

18 enrolled 2 charts

Gastrointestinal Cancer Metastatic

NCT00957905 2017-03-10

Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors

36 enrolled 7 charts

Testicular Neoplasms

NCT01183663 2016-06-03

Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX)

BreastCNSDermatologicGastrointestinalGenitourinaryOther hematologic neoplasmPlasma cell

180 enrolled

Breast Neoplasms, Carcinoma, Renal Cell, Colonic Neoplasms, Glioblastoma, Melanoma, Multiple Myeloma, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms

NCT00413322 2015-07-08

Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

35 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Carcinosarcoma, Chondrosarcoma, Solitary Pulmonary Nodule, Phyllodes Tumor, Esophageal Neoplasms, Facial Neoplasms, Fibrosarcoma, Head and Neck Neoplasms, Hemangiosarcoma, Kidney Neoplasms, Leiomyosarcoma, Liposarcoma, Lung Neoplasms, Lymphangiosarcoma, Mesothelioma, Mouth Neoplasms, Myosarcoma, Myxosarcoma, Neoplasms, Otorhinolaryngologic Neoplasms, Ovarian Neoplasms, Pancoast Syndrome, Parathyroid Neoplasms, Sarcoma, Osteosarcoma, Thyroid Neoplasms, Tracheal Neoplasms, Colorectal Neoplasms, Adenosarcoma, Mixed Tumor, Mesodermal, Mesothelioma, Cystic, Carcinoma, Small Cell, Pulmonary Sclerosing Hemangioma, Histiocytoma, Malignant Fibrous

NCT00083109 2015-05-25

Fluorouracil and Low-Dose Suramin as Chemosensitization in Treating Patients With Metastatic Renal Cell (Kidney) Cancer

Phase 1/2 Completed

36 enrolled

Carcinoma, Renal Cell

NCT00053820 2013-12-19

Interferon Alfa With or Without Interleukin-2 and Fluorouracil in Treating Patients With Advanced Metastatic Kidney Cancer

Phase 3 Completed

670 enrolled

Carcinoma, Renal Cell, Kidney Neoplasms

NCT00024349 2013-12-18

Radiation Therapy With or Without Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer

Phase 3 Completed

350 enrolled

Urinary Bladder Neoplasms

NCT00003585 2013-12-10

Biological Therapy Plus Chemotherapy in Treating Patients With Metastatic or Recurrent Kidney Cancer

Phase 1/2 Completed

35 enrolled

Carcinoma, Renal Cell, Kidney Neoplasms

NCT00003175 2013-12-04

Fluorouracil in Treating Patients With Recurrent or Metastatic Bladder Cancer

45 enrolled

Urinary Bladder Neoplasms, Urethral Neoplasms

NCT00003664 2013-11-06

Combination Chemotherapy and Biological Therapy In Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed Surgically

Phase 2 Unknown

30 enrolled

GastrointestinalGenitourinary

Carcinoma, Renal Cell, Kidney Neoplasms

NCT00016042 2013-09-20

Fluorouracil and Biological Therapy in Treating Patients With Metastatic Kidney or Colorectal Cancer

Phase 1 Unknown

Carcinoma, Renal Cell, Colonic Neoplasms, Kidney Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00030342 2013-06-26

Biological Therapy and Chemotherapy in Treating Patients With Metastatic Kidney Cancer or Colorectal Cancer

Phase 1/2 Completed

60 enrolled

GastrointestinalGenitourinary

Carcinoma, Renal Cell, Colonic Neoplasms, Kidney Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00053807 2012-09-24

Interleukin-2, Interferon Alfa, and Fluorouracil Compared With Observation in Treating Patients Who Have Undergone Surgery for Kidney Cancer

Phase 3 Completed

96 enrolled

Carcinoma, Renal Cell, Kidney Neoplasms

NCT00054977 2012-03-12

Safety of GM-CT-01 With and Without 5-Fluorouracil in Patients With Solid Tumors

BreastGastrointestinalGenitourinaryHead & NeckThoracic

40 enrolled

Breast Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT00003642 2012-03-06

Radiation Therapy and Chemotherapy Following Surgery in Treating Patients With Stage II or Stage III Bladder Cancer

Phase 2 Terminated

43 enrolled

Urinary Bladder Neoplasms

NCT00154687 2007-07-31

Weekly TP-HDFL in the Treatment of Advanced TCC

40 enrolled