Announcements Trials
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Phase

Phase 2 3Phase 1/2 1Phase 1 1

Status

Terminated 4Recruiting 1

Sponsor Class

OTHER 4INDUSTRY 1

Study Type

Interventional 5

Sponsor

Cancer Type

Plasma cell 49Lymphoid 29Other hematologic neoplasm 27Sarcoma 14Gastrointestinal 9Myeloid 8Gynecologic 8CNS 8Thoracic 7Dermatologic 6Genitourinary 5Breast 3Other solid neoplasm 2Tumor-Agnostic 1Head & Neck 1Endocrine 1

Conditions

Wilms Tumor 1Triple Negative Breast Neoplasms 1Rhabdoid Tumor 1Prostatic Neoplasms 1Ovarian Neoplasms 1Neurofibrosarcoma 1Neoplasm Metastasis 1Melanoma 1Lung Neoplasms 1Fallopian Tube Neoplasms 1Castration Levels of Testosterone 1Carcinoma, Transitional Cell 1Carcinoma, Renal Cell 1Carcinoma, Non-Small-Cell Lung 1

Interventions

Docetaxel 409pembrolizumab 332Prednisone 290enzalutamide 285Gemcitabine 274Radiotherapy 270Magnetic Resonance Spectroscopy 269Nivolumab 253Abiraterone Acetate 218Cisplatin 212Leuprolide 195Radiosurgery 192Sunitinib 188Carboplatin 161Androgen Antagonists 156bicalutamide 152Specimen Handling 149Goserelin 149Ipilimumab 131Paclitaxel 126acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide 122apalutamide 118Cyclophosphamide 117Bevacizumab 116Sorafenib 114Everolimus 111abiraterone 108cabozantinib 105atezolizumab 105Biopsy 101

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
selinexor × Genitourinary × Clear all
NCT05985161 2026-05-06

A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

Memorial Sloan Kettering Cancer Center

Phase 2 Recruiting
45 enrolled
GenitourinarySarcoma

Wilms Tumor, Neurofibrosarcoma, Rhabdoid Tumor

NCT04856189 2026-01-29

Selinexor and Pembrolizumab for the Treatment of Cisplatin-Ineligible or Cisplatin-Refractory Locally Advanced or Metastatic Urothelial Carcinoma

University of California, Davis

Phase 1/2 Terminated
4 enrolled 8 charts
Genitourinary

Carcinoma, Transitional Cell

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

M.D. Anderson Cancer Center

Phase 1 Terminated
221 enrolled
BreastDermatologicGenitourinaryGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT02146833 2023-01-26

SHIP

Karyopharm Therapeutics Inc

Phase 2 Terminated
20 enrolled 13 charts
Genitourinary

Prostatic Neoplasms

NCT02215161 2018-06-26

Selinexor in Treating Patients With Abiraterone Acetate and/or Enzalutamide Refractory Metastatic Castration-Resistant Prostate Cancer

University of California, San Francisco

Phase 2 Terminated
14 enrolled 12 charts
Genitourinary

Castration Levels of Testosterone

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