Clinical Trials

42 enrolled

Prostatic Neoplasms

NCT01834001 2026-04-15

Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy

300 enrolled

Prostatic Neoplasms

NCT05155046 2026-04-15

18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy

130 enrolled

Localized Prostate Cancer

NCT05987241 2026-04-15

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Phase 2/3 Recruiting

992 enrolled

Muscle Invasive Bladder Urothelial Carcinoma

NCT06161506 2026-04-15

Surface Electrical Stimulation for Urinary Incontinence in Men Treated for Prostate Cancer

41 enrolled

Prostatic Hyperplasia, Prostatic Neoplasms, Urinary Incontinence, Urinary Incontinence, Stress, Urinary Incontinence, Urge

NCT06524544 2026-04-15

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Phase 3 Recruiting

320 enrolled

Carcinoma, Transitional Cell

NCT06770582 2026-04-15

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

160 enrolled

Urinary Bladder Neoplasms

NCT00001823 2026-04-14

Evaluation for NCI Surgery Branch Clinical Research Protocols

DermatologicGastrointestinalGenitourinaryThoracic

7,000 enrolled

Urinary Bladder Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Colorectal Neoplasms

NCT00026884 2026-04-14

Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease

5,950 enrolled

Urinary Bladder Neoplasms, Kidney Neoplasms, Neoplasms, Neoplastic Syndromes, Hereditary

NCT00033137 2026-04-14

Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

950 enrolled

Kidney Neoplasms, Neoplasms, Pneumothorax

NCT00034216 2026-04-14

Collection of Blood From Patients With Cancer

BreastGastrointestinalGenitourinaryThoracic

1,750 enrolled

Breast Neoplasms, Colonic Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms, Prostatic Neoplasms

NCT00050752 2026-04-14

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

1,130 enrolled

Kidney Neoplasms, Leiomyoma

NCT00923221 2026-04-14

Collection of Blood From Patients With Prostate Cancer

1,000 enrolled

Prostatic Neoplasms

NCT01109394 2026-04-14

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

CNSGenitourinaryOther solid neoplasmSarcoma

6,035 enrolled

Kidney Neoplasms, Neoplasms, Neuroblastoma, Retinoblastoma, Sarcoma

NCT01441089 2026-04-14

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

BreastGenitourinaryGynecologicLymphoidThoracic

1,100 enrolled

Breast Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms

NCT04628767 2026-04-14

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Phase 2/3 Recruiting

249 enrolled

Renal Pelvis and Ureter Urothelial Carcinoma

NCT04706663 2026-04-14

Precision-Based Genomics in Prostate Cancer

2,000 enrolled

Prostatic Neoplasms, Genetic Predisposition to Disease

NCT05588128 2026-04-14

Prospective Monitoring of Subjects With Biochemically Recurrent Prostate Cancer Using 18FDCFPyL

350 enrolled

Prostatic Neoplasms

NCT06161532 2026-04-14

Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...

60 enrolled

Carcinoma, Transitional Cell

NCT04071236 2026-04-13

Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive to Hormonal Therapy

90 enrolled

Lymphatic Metastasis, Prostatic Neoplasms

NCT04550494 2026-04-13

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

BreastGastrointestinalGenitourinaryGynecologic

36 enrolled

Breast Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms

NCT05691465 2026-04-13

Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

30 enrolled

Prostatic Neoplasms

NCT06022822 2026-04-13

Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial

90 enrolled

Prostate Adenocarcinoma

NCT06439836 2026-04-13

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Phase 1 Recruiting

27 enrolled

BreastGastrointestinalGenitourinaryGynecologicThoracic

Carcinoma, Transitional Cell

NCT06995898 2026-04-13

The Vanguard Study: Testing a New Way to Screen for Cancer

Phase NA Recruiting

24,000 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT07061964 2026-04-13

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

111 enrolled

Urinary Bladder Neoplasms

NCT04633252 2026-04-08

A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer

86 enrolled

Prostatic Neoplasms

NCT00451022 2026-04-07

Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies

BreastGastrointestinalGenitourinaryThoracic

750 enrolled

Breast Neoplasms, Colonic Neoplasms, Liver Neoplasms, Lung Neoplasms, Prostatic Neoplasms

NCT04981509 2026-04-07

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

65 enrolled

Hereditary leiomyomatosis and renal cell cancer, Papillary renal cell carcinoma, sporadic, Carcinoma, Renal Cell

NCT05665361 2026-04-07

Palbociclib and Sasanlimab for the Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Papillary Renal Cell Carcinoma (pRCC)

100 enrolled

Carcinoma, Renal Cell, Kidney Neoplasms

NCT02830724 2026-04-06

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

BreastDermatologicGastrointestinalGenitourinaryGynecologic

124 enrolled

Breast Neoplasms, Carcinoma, Renal Cell, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms

NCT03354416 2026-04-06

Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer

10,000 enrolled

Prostatic Hyperplasia, Prostatic Neoplasms

NCT04235764 2026-04-06

En-bloc Transurethral Resection of Bladder Tumor (En-bloc TURBT) Specimens Using a Redesigned Surgical Resectoscope Device

25 enrolled

Urinary Bladder Neoplasms

NCT05361798 2026-04-06

A Phase II Study Evaluating T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine PDS01ADC in Localized High and Intermediate Risk Prostate Cancer Treated With Androgen Deprivation Therapy

65 enrolled

Prostatic Neoplasms

NCT02379429 2026-04-02

Care of the Urothelial Cancer Patient and Prospective Procurement of Urothelial Cancer Tissue

500 enrolled

Urinary Bladder Neoplasms, Urologic Neoplasms

NCT00001238 2026-03-31

Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

5,000 enrolled

EndocrineGenitourinary

Hereditary leiomyomatosis and renal cell cancer, Carcinoma, Renal Cell, Kidney Neoplasms, Pheochromocytoma

NCT02594202 2026-03-27

Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue

3,000 enrolled

Prostatic Neoplasms, Carcinogenesis

NCT04235777 2026-03-27

Bintrafusp Alfa (M7824) and PDS01ADC Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies

Phase 1 Recruiting

100 enrolled

Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Urogenital Neoplasms

NCT04692675 2026-03-27

Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer

Phase NA Recruiting

508 enrolled

Prostatic Neoplasms, Disease Progression

NCT06503146 2026-03-27

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection