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Phase

Phase 1/2 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 1Gynecologic 1Gastrointestinal 1

Conditions

Uterine Cervical Neoplasms 2Endometrial Neoplasms 2Vulvar Neoplasms 1Vulvar Diseases 1Uterine Cervical Dysplasia 1Rectal Neoplasms 1Papillomavirus Infections 1Ovarian Neoplasms 1Oropharyngeal Neoplasms 1Lung Neoplasms 1Head and Neck Neoplasms 1Esophageal Neoplasms 1Cystadenocarcinoma, Serous 1Carcinoma in Situ 1Breast Neoplasms 1Anus Neoplasms 1

Interventions

Cyclophosphamide 8pembrolizumab 7fludarabine 6aldesleukin 4Papillomavirus Vaccines 4Vaccines 3Radiotherapy 3Light Coagulation 3Biopsy 3spartalizumab 2fludarabine phosphate 2entinostat 2Watchful Waiting 2Vorinostat 2VGX-3100 2Trastuzumab 2Tomography, X-Ray Computed 2Surveys and Questionnaires 2Paclitaxel 2Observation 2Nivolumab 2Interleukin-2 2Interleukin-12 Subunit p35 2Early Intervention, Educational 2Drug Therapy 2Carboplatin 2Adoptive Transfer 2trastuzumab deruxtecan 1tislelizumab 1tipifarnib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Anus Neoplasms × Diphenhydramine × Gynecologic × Clear all
NCT04432597 2026-05-18

HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Active not recruiting
39 enrolled
GastrointestinalGynecologicHead & Neck

Anus Neoplasms, Uterine Cervical Neoplasms, Oropharyngeal Neoplasms, Rectal Neoplasms

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