Clinical Trials

Breast Neoplasms, Ovarian Neoplasms, Uterine Neoplasms

NCT00043472 2026-04-07

Removal of the Ovaries/Fallopian Tubes and CA-125 Screening to Reduce the Risk of Ovarian Cancer in Women at Increased Genetic Risk

40 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologic

Breast Neoplasms, Neoplasms, Ovarian Neoplasms

NCT02830724 2026-04-06

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

Phase 1/2 Recruiting

124 enrolled

Breast Neoplasms, Carcinoma, Renal Cell, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms

NCT06253520 2026-04-06

Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer

Phase 1 Active not recruiting

210 enrolled

BreastGastrointestinalGynecologicThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Ovarian Neoplasms, Urogenital Neoplasms, Colorectal Neoplasms

NCT01174121 2026-03-04

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

Phase 2 Recruiting

332 enrolled

Breast Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Urogenital Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT01273168 2025-12-23

Endoxifen in Adults With Hormone Receptor Positive Solid Tumors

BreastGynecologicThoracic

40 enrolled

BreastGynecologicSarcoma

Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Uterine Neoplasms, Endometrial Neoplasms, Desmoid Tumors

NCT04102436 2024-03-12

Non-Viral TCR Gene Therapy

Phase 2 Withdrawn

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Urogenital Neoplasms

NCT00342446 2024-01-11

A Follow-up Study of Women Evaluated and Treated for Infertility

BreastDermatologicGastrointestinalGynecologicHead & Neck

12,193 enrolled

Breast Neoplasms, Melanoma, Ovarian Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT00001503 2023-06-18

Follow-up Protocol for Patients With Cancer/AIDS/Skin Disease

BreastDermatologicGenitourinaryGynecologicLymphoid

1,031 enrolled

Breast Neoplasms, Lymphoma, Melanoma, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms

NCT02203513 2022-09-10

A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer

Phase 2 Terminated

111 enrolled 15 charts

BreastGenitourinaryGynecologic

Breast Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT02111850 2022-03-29

T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positive

Phase 1/2 Completed

21 enrolled 22 charts

BreastDermatologicGenitourinaryGynecologic

Breast Neoplasms, Uterine Cervical Neoplasms, Kidney Neoplasms, Melanoma

NCT02179515 2021-01-26

Safety and Tolerability of a Modified Vaccinia Ankara (MVA)-Based Vaccine Modified to Express Brachyury and T-cell Costimulatory Molecules (MVA-Brachyury-TRICOM)

BreastGenitourinaryGynecologicThoracic

38 enrolled 20 charts

Breast Neoplasms, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms

NCT00340600 2020-11-16

Continuation of Follow-up of DES-Exposed Cohorts

BreastGenitourinaryGynecologic

10,805 enrolled

Autoimmune Diseases, Breast Neoplasms, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT00340210 2020-09-10

Extended Follow-up of Columbia, MO Serum Bank Participants

6,720 enrolled

Breast Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT00341458 2020-04-20

Breast Cancer in Poland: An Expanded Study to Assess Occupational and Environmental Factors and Interactions With Genetics

6,086 enrolled

Breast Neoplasms, Gonadal Disorders, Ovarian Neoplasms, Uterine Diseases, Endometrial Neoplasms

NCT00340262 2020-03-30

Bone Mineral Density and Subsequent Cancer Risk

15,595 enrolled

Breast Neoplasms, Osteoporosis, Endometrial Neoplasms

NCT01237067 2019-12-17

Olaparib in Combination With Carboplatin for Refractory or Recurrent Women s Cancers

77 enrolled

BreastDermatologicGastrointestinalGynecologic

Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Recurrence, Endometrial Neoplasms

NCT03300843 2019-12-13

Ability of a Dendritic Cell Vaccine to Immunize Melanoma or Epithelial Cancer Patients Against Defined Mutated Neoantigens Expressed by the Autologous Cancer

Phase 2 Terminated

1 enrolled 7 charts

Breast Neoplasms, Gastrointestinal Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms

NCT00001806 2019-12-12

Methods in Education for Breast Cancer Genetics

Phase 3 Completed

170 enrolled

BreastClassical hematologyGynecologic

Fanconi Anemia, Complementation Group D1, Breast Neoplasms, Ovarian Neoplasms

NCT01374685 2019-12-03

Family Communication of Hereditary Breast and Ovarian Cancer Risk Among African Americans

Terminated

8 enrolled

Breast Neoplasms, Ovarian Neoplasms

NCT01445418 2019-10-22

AZD2281 Plus Carboplatin to Treat Breast and Ovarian Cancer

103 enrolled

BreastDermatologicGenitourinaryGynecologic

Breast Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT02153905 2019-06-17

T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-A*01 Positive

Phase 1/2 Terminated

3 enrolled 14 charts

Urinary Bladder Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Kidney Neoplasms, Melanoma, Neoplasm Metastasis

NCT00088413 2019-04-16

PANVAC-V and PANVAC-F Vaccines Plus Sargramostim to Treat Advanced Cancer

Phase 1/2 Completed

51 enrolled 20 charts

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmOther solid neoplasmThoracic

Adenocarcinoma, Breast Neoplasms, Neoplasms, Ovarian Neoplasms, Colorectal Neoplasms

NCT00904514 2018-10-05

Study of Previously Collected and Stored Tissue Samples From Patients Previously Enrolled in a Completed National Cancer Institute Clinical Trial

Terminated

241 enrolled

Congenital Abnormalities, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Mesothelioma, Malignant, Urinary Bladder Neoplasms, Breast Neoplasms, Brenner Tumor, Burkitt Lymphoma, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Fallopian Tube Neoplasms, Hodgkin Disease, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Mycosis Fungoides, Neoplasms, Pancreatic Neoplasms, Salivary Gland Neoplasms, Sezary Syndrome, Stomach Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic, Leukemia, Myeloid, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT01437007 2018-08-03

TKM 080301 for Primary or Secondary Liver Cancer

1 enrolled

Adenocarcinoma, Breast Neoplasms, Disease, Liver Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT00892736 2018-06-29

Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy

BreastGastrointestinalGenitourinaryGynecologic

98 enrolled

Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome, Triple Negative Breast Neoplasms

NCT01145430 2017-12-22

Veliparib and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer or Metastatic Breast Cancer

45 enrolled

Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT00001898 2017-07-02

Microarray Analysis for Human Genetic Disease

BreastDermatologicGynecologic

1,500 enrolled

Breast Neoplasms, Melanoma, Neoplastic Syndromes, Hereditary, Ovarian Neoplasms

NCT01386502 2017-07-02

CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors

Phase 1 Withdrawn

BreastGastrointestinalGynecologicSarcoma

Breast Neoplasms, Colonic Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Sarcoma

NCT01306032 2017-04-26

Phase II ABT-888 With Cyclophosphamide

Phase 2 Completed

124 enrolled 21 charts

Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT02627430 2016-07-26

Talazoparib and HSP90 Inhibitor AT13387 in Treating Patients With Metastatic Advanced Solid Tumor or Recurrent Ovarian, Fallopian Tube, Primary Peritoneal, or Triple Negative Breast Cancer

Phase 1 Withdrawn

Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT00182767 2016-03-10

Ixabepilone and Liposomal Doxorubicin in Advanced Ovarian Cancer

Phase 1/2 Completed

45 enrolled 8 charts

BreastCNSDermatologicGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cell

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Fallopian Tube Neoplasms

NCT00060021 2015-04-30

Acupuncture in Treating Mucositis-Related Pain Caused by Chemotherapy in Patients Undergoing Stem Cell Transplantation

Phase NA Completed

Teratoma, Testicular, Pdgfra-Associated Chronic Eosinophilic Leukemia, Carcinoma, Ovarian Epithelial, Blast Crisis, Breast Neoplasms, Burkitt Lymphoma, Hodgkin Disease, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Mycosis Fungoides, Myeloproliferative Disorders, Neoplasms, Neuroblastoma, Pain, Sezary Syndrome, Teratoma, Testicular Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Carcinoma, Embryonal, Seminoma, Endodermal Sinus Tumor, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT01131234 2014-12-23

Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicSarcomaThoracic

20 enrolled

Astrocytoma, Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Ependymoma, Glioblastoma, Glioma, Melanoma, Oligodendroglioma, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Gliosarcoma, Breast Neoplasms, Male

NCT01233505 2014-04-02

Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors

Phase 1 Terminated

16 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Colonic Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT00348699 2014-02-24

AFP464 in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery

BreastGenitourinaryGynecologic

68 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Renal Cell, Breast Neoplasms, Male

NCT00769613 2013-12-18

Emergency Use of Donor Lymphocytes in Treating Patients Who Have Undergone Donor Stem Cell Transplant and Have Cytomegalovirus Infections

Phase 1 Unknown

20 enrolled

BreastCNSDermatologicGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Carcinoma, Ovarian Epithelial, Blast Crisis, Breast Neoplasms, Burkitt Lymphoma, Cytomegalovirus Infections, Hodgkin Disease, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Mycosis Fungoides, Myeloproliferative Disorders, Neoplasms, Wilms Tumor, Neuroblastoma, Recurrence, Sezary Syndrome, Testicular Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Dendritic Cell Sarcoma, Interdigitating, Primary Myelofibrosis

NCT00002465 2013-11-06

High-Dose Megestrol in Treating Patients With Metastatic Breast Cancer, Endometrial Cancer, or Mesothelioma

Phase 1/2 Unknown

BreastGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Breast Neoplasms, Endometrial Neoplasms

NCT00031681 2013-09-30

7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)

BreastCNSGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

41 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Esthesioneuroblastoma, Olfactory, Gastrointestinal Stromal Tumors, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT00321633 2013-08-26

Carboplatin or Docetaxel in Treating Women With Metastatic Genetic Breast Cancer

Phase 2 Completed

148 enrolled

BreastGenitourinaryGynecologicSarcoma

Breast Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT00601406 2013-08-26

Study of DNA Mutations in Predicting the Effect of External-Beam Radiation Therapy in Patients With Early Breast Cancer, Localized Prostate Cancer, or Gynecological Cancer

Phase NA Unknown

2,200 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Sarcoma, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms, Breast Neoplasms, Male

NCT00632047 2013-08-26

Early Detection of Breast Cancer and Cervical Cancer in Women in India

Phase 2 Unknown

151,538 enrolled