Announcements Trials
Browse Landscape

Phase

Phase 3 2Phase 2 1Phase 1 1

Status

Completed 3Available 1Active not recruiting 1

Sponsor Class

INDUSTRY 4OTHER 1

Study Type

Interventional 4Expanded_access 1

Sponsor

Cancer Type

Gynecologic 5Sarcoma 1Plasma cell 1Myeloid 1Lymphoid 1

Conditions

Endometrial Neoplasms 5Ovarian Neoplasms 4Sarcoma 2Uterine Neoplasms 1Uterine Diseases 1Uterine Cervical Neoplasms 1Triple Negative Breast Neoplasms 1Sarcoma, Endometrial Stromal 1Recurrence 1Primary Myelofibrosis 1Neurofibrosarcoma 1Neoplasms by Site 1Neoplasms 1Neoplasm Metastasis 1Multiple Myeloma 1Melanoma 1Lymphoma, T-Cell, Peripheral 1Lymphoma, Large B-Cell, Diffuse 1Lung Neoplasms 1Leiomyosarcoma 1Genital Diseases 1Fallopian Tube Neoplasms 1Carcinoma, Renal Cell 1Carcinoma, Non-Small-Cell Lung 1

Interventions

Paclitaxel 95Carboplatin 77pembrolizumab 74Cisplatin 29Bevacizumab 27Surveys and Questionnaires 23Radiotherapy 22Letrozole 22Doxorubicin 21Megestrol Acetate 20olaparib 19lenvatinib 19Taxes 17Specimen Handling 17Docetaxel 17Nivolumab 16Magnetic Resonance Spectroscopy 16dostarlimab 15Metformin 15Blood Specimen Collection 14Observation 13Gemcitabine 13Biopsy 13durvalumab 12Medroxyprogesterone Acetate 12Trastuzumab 11Indocyanine Green 11Fulvestrant 11temsirolimus 10abemaciclib 10

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Endometrial Neoplasms × selinexor × Gynecologic × Clear all
NCT05611931 2026-05-29

XPORT-EC-042

Karyopharm Therapeutics Inc

Phase 3 Active not recruiting
257 enrolled
Gynecologic

Endometrial Neoplasms

NCT03555422 2026-04-13

ENGOT-EN5

Karyopharm Therapeutics Inc

Phase 3 Completed
263 enrolled
Gynecologic

Genital Diseases, Neoplasms, Neoplasms by Site, Uterine Diseases, Uterine Neoplasms, Endometrial Neoplasms

NCT07215832 2026-03-02

KEAP

Karyopharm Therapeutics Inc

Available
GynecologicLymphoidMyeloidPlasma cellSarcoma

Multiple Myeloma, Sarcoma, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Peripheral, Endometrial Neoplasms, Primary Myelofibrosis

NCT02025985 2023-01-26

SIGN

Karyopharm Therapeutics Inc

Phase 2 Completed
116 enrolled 21 charts
Gynecologic

Uterine Cervical Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT02269293 2021-04-23

Selective Inhibitor of Nuclear Export, Selinexor (KPT-330) in Combination With Paclitaxel and Carboplatin in Patients With Advanced Ovarian or Endometrial Cancers

Memorial Sloan Kettering Cancer Center

Phase 1 Completed
23 enrolled
Gynecologic

Ovarian Neoplasms, Endometrial Neoplasms

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