Clinical Trials

BreastGastrointestinalGynecologicHead & NeckSarcoma

Carcinosarcoma, Endometrial Neoplasms

NCT04704661 2026-04-13

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Phase 1 Recruiting

51 enrolled

Breast Neoplasms, Carcinosarcoma, Colonic Neoplasms, Neoplasm Metastasis, Salivary Gland Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT05554328 2026-04-13

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

Phase 2 Recruiting

165 enrolled

Phase 1 Active not recruiting

Fallopian Tube Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT05691504 2026-04-13

Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers

42 enrolled

Carcinosarcoma, Fallopian Tube Neoplasms, Endometrial Neoplasms

NCT05950464 2026-04-13

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

Phase 1 Recruiting

60 enrolled

Endometrial Neoplasms

NCT07198074 2026-04-13

Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

Phase 3 Recruiting

255 enrolled

Endometrial Neoplasms

NCT06253494 2026-04-09

Pembrolizumab, Lenvatinib and IL-15 Superagonist N-803 in Combination With HER2 Targeting Autologous Dendritic Cell (AdHER2DC) Vaccine in Participants With Advanced or Metastatic Endometrial Cancer

Phase 1/2 Recruiting

60 enrolled

BreastGastrointestinalGynecologic

Endometrial Neoplasms

NCT01174121 2026-03-04

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

Phase 2 Recruiting

332 enrolled

Breast Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Urogenital Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT01273168 2025-12-23

Endoxifen in Adults With Hormone Receptor Positive Solid Tumors

40 enrolled

BreastGynecologicSarcoma

Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Uterine Neoplasms, Endometrial Neoplasms, Desmoid Tumors

NCT00924027 2025-09-05

A Study of Patients Receiving High-Dose Rate Brachytherapy

GastrointestinalGenitourinaryGynecologic

43 enrolled 13 charts

Biliary Tract Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT03300557 2025-08-29

Exemestane in Treating Patients With Complex Atypical Hyperplasia of the Endometrium/Endometrial Intraepithelial Neoplasia or Low Grade Endometrial Cancer

40 enrolled 13 charts

Phase 2 Active not recruiting

Endometrial Hyperplasia, Endometrial Neoplasms

NCT03367741 2025-07-28

Cabozantinib S-malate and Nivolumab in Treating Patients With Advanced, Recurrent, or Metastatic Endometrial Cancer

82 enrolled

Carcinosarcoma, Endometrial Neoplasms

NCT00342446 2024-01-11

A Follow-up Study of Women Evaluated and Treated for Infertility

BreastDermatologicGastrointestinalGynecologicHead & Neck

12,193 enrolled

Breast Neoplasms, Melanoma, Ovarian Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT03394027 2022-08-23

ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma

30 enrolled 15 charts

Neoplasm Metastasis, Endometrial Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT00879840 2020-11-17

Assessment of Screening Modalities for Gynecologic Cancers

118 enrolled

Ovarian Neoplasms, Endometrial Neoplasms

NCT01793545 2020-11-17

Endometrial Cancer Testing With Vaginal and Endometrial Cell Samples

1,932 enrolled

Endometrial Neoplasms

NCT00340600 2020-11-16

Continuation of Follow-up of DES-Exposed Cohorts

BreastGenitourinaryGynecologic

10,805 enrolled

Autoimmune Diseases, Breast Neoplasms, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT00340210 2020-09-10

Extended Follow-up of Columbia, MO Serum Bank Participants

6,720 enrolled

Breast Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT00339651 2020-08-14

Preliminary Study of Endometrial Hyperplasia Groundwork for a Study to Define Precursors of Endometrial Cancer

745 enrolled

Endometrial Hyperplasia, Hyperplasia, Uterine Hemorrhage, Endometrial Neoplasms, Disease Progression

NCT00340808 2020-07-17

Molecular Staging of Endometrial Cancer

5,492 enrolled

Endometrial Neoplasms

NCT00341458 2020-04-20

Breast Cancer in Poland: An Expanded Study to Assess Occupational and Environmental Factors and Interactions With Genetics

6,086 enrolled

Breast Neoplasms, Gonadal Disorders, Ovarian Neoplasms, Uterine Diseases, Endometrial Neoplasms

NCT00340262 2020-03-30

Bone Mineral Density and Subsequent Cancer Risk

15,595 enrolled

Breast Neoplasms, Osteoporosis, Endometrial Neoplasms

NCT01237067 2019-12-17

Olaparib in Combination With Carboplatin for Refractory or Recurrent Women s Cancers

77 enrolled

Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Recurrence, Endometrial Neoplasms

NCT00095979 2019-07-24

Ixabepilone in Treating Patients With Recurrent or Persistent Endometrial Cancer

52 enrolled 10 charts

Endometrial Neoplasms

NCT00096447 2019-07-24

Lapatinib in Treating Patients With Recurrent or Persistent Endometrial Cancer

31 enrolled 13 charts

Endometrial Neoplasms

NCT00301964 2019-07-24

Bevacizumab in Treating Patients With Recurrent or Persistent Endometrial Cancer

56 enrolled 13 charts

Endometrial Neoplasms

NCT00416455 2019-07-23

Fludeoxyglucose (FDG) F 18 PET Scan, CT Scan, and Ferumoxtran-10 MRI Scan Before Chemotherapy and Radiation Therapy in Finding Lymph Node Metastasis in Patients With Locally Advanced Cervical Cancer or High-Risk Endometrial Cancer

Phase 1/2 Completed

384 enrolled 23 charts

Uterine Cervical Neoplasms, Endometrial Neoplasms

NCT00462826 2019-07-23

VEGF Trap in Treating Patients With Recurrent or Persistent Endometrial Cancer

49 enrolled 13 charts

Endometrial Neoplasms

NCT00723255 2019-07-23

Bevacizumab and Temsirolimus in Treating Patients With Recurrent or Persistent Endometrial Cancer

53 enrolled 15 charts

Endometrial Neoplasms

NCT00729586 2019-07-23

Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial Cancer

73 enrolled 13 charts

Endometrial Neoplasms

NCT01216813 2016-11-01

Study of Physical and Psychosocial Rehabilitation Needs of Patients After Diagnosis and Treatment of Upper Gastrointestinal Cancer or Gynecological Cancer

GastrointestinalGynecologicSarcoma

33 enrolled

Carcinoma, Ovarian Epithelial, Uterine Cervical Neoplasms, Esophageal Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms

NCT00072176 2015-02-23

Temsirolimus in Treating Patients With Metastatic or Locally Advanced Recurrent Endometrial Cancer

62 enrolled 7 charts

Endometrial Neoplasms

NCT00408655 2014-06-19

Temsirolimus, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Tumors

38 enrolled

Carcinoma, Ovarian Epithelial, Endometrial Neoplasms

NCT01198184 2014-05-30

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 and Temsirolimus in Treating Patients With Advanced Solid Tumors

18 enrolled

GenitourinaryGynecologic

Carcinoma, Renal Cell, Endometrial Neoplasms

NCT00030485 2014-01-27

Erlotinib in Treating Patients With Locally Advanced and/or Metastatic Endometrial Cancer

Endometrial Neoplasms

NCT00003560 2014-01-06

Docetaxel Plus Carboplatin in Treating Patients With Stage III or Stage IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

40 enrolled

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT00003718 2014-01-06

Temozolomide in Treating Patients With Advanced Soft Tissue Sarcoma

25 enrolled

Malignant mesenchymal tumor, Hemangiopericytoma, Malignant, Chondrosarcoma, Extraskeletal Myxoid, Fibrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Ovarian Neoplasms, Rhabdomyosarcoma, Sarcoma, Sarcoma, Synovial, Endometrial Neoplasms, Sarcoma, Endometrial Stromal, Sarcoma, Alveolar Soft Part, Neurofibrosarcoma, Histiocytoma, Malignant Fibrous

NCT00003749 2013-12-19

Surgery With or Without Lymphadenectomy and Radiation Therapy in Treating Patients With Endometrial Cancer

Phase 3 Completed

2,300 enrolled

BreastGynecologicOther solid neoplasmThoracic

Endometrial Neoplasms

NCT00002465 2013-11-06

High-Dose Megestrol in Treating Patients With Metastatic Breast Cancer, Endometrial Cancer, or Mesothelioma

Phase 1/2 Unknown

Mesothelioma, Malignant, Breast Neoplasms, Endometrial Neoplasms

NCT00031681 2013-09-30

7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)

BreastCNSGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

41 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Anus Neoplasms, Appendiceal Neoplasms, Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Esthesioneuroblastoma, Olfactory, Gastrointestinal Stromal Tumors, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT00601406 2013-08-26

Study of DNA Mutations in Predicting the Effect of External-Beam Radiation Therapy in Patients With Early Breast Cancer, Localized Prostate Cancer, or Gynecological Cancer

Phase NA Unknown

2,200 enrolled

BreastGenitourinaryGynecologicSarcoma

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Sarcoma, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms, Breast Neoplasms, Male

NCT00737230 2013-08-26

Care of Cancer Patients With Bowel Injury Caused by Radiation Therapy to the Pelvis

Phase NA Completed

250 enrolled

GastrointestinalGenitourinaryGynecologic

Anus Neoplasms, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Neoplasms, Prostatic Neoplasms, Radiation Injuries, Rectal Neoplasms, Testicular Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms

NCT00758056 2013-08-26

Study of Genes and the Environment in Patients With Endometrial Cancer in the East Anglia, Oxford, Trent, or West Midlands Regions of the United Kingdom

Unknown

2,000 enrolled

Endometrial Neoplasms

NCT00637637 2013-08-12

External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmSarcomaThoracic

60 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Thyroid Cancer, Papillary, Anus Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Burkitt Lymphoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Hodgkin Disease, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mouth Neoplasms, Mycosis Fungoides, Nasopharyngeal Neoplasms, Neoplasms, Wilms Tumor, Oropharyngeal Neoplasms, Pancreatic Neoplasms, Parathyroid Neoplasms, Penile Neoplasms, Pheochromocytoma, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Sezary Syndrome, Stomach Neoplasms, Tongue Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Endometrial Neoplasms, Lymphoma, Large-Cell, Anaplastic, Adenocarcinoma, Follicular, Adrenocortical Carcinoma, Esthesioneuroblastoma, Olfactory, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Histiocytoma, Malignant Fibrous, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

NCT01100359 2013-08-07

Liposome-Encapsulated Doxorubicin Citrate and Carboplatin in Treating Patients With Advanced or Metastatic Recurrent Endometrial Cancer

39 enrolled