Clinical Trials

BreastDermatologicEndocrineGynecologicHead & Neck

78 enrolled

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Uterine Cervical Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms, Adrenocortical Carcinoma, Triple Negative Breast Neoplasms

NCT05454358 2025-12-15

Letrozole as Maintenance Therapy for Post-surgical Endometrial Cancer Patients With NSMP

Phase 2/3 Terminated

12 enrolled

Endometrial Neoplasms

NCT05252416 2025-11-28

(VELA) Study of BLU-222 in Advanced Solid Tumors

GastrointestinalGynecologicSarcoma

50 enrolled

Adenocarcinoma Of Esophagus, Carcinosarcoma, Ovarian Neoplasms, Stomach Neoplasms, Endometrial Neoplasms

NCT05194735 2025-11-10

Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors

GastrointestinalGynecologicThoracic

8 enrolled 12 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT05798611 2025-11-06

ARTIST

36 enrolled

Neoplasm Metastasis, Endometrial Neoplasms

NCT05169437 2025-10-29

PAVO

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

22 enrolled 17 charts

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Urologic Neoplasms, Endometrial Neoplasms

NCT04272034 2025-10-16

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

105 enrolled

Nasopharyngeal Carcinoma, Esophageal Squamous Cell Carcinoma, Anus Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Mesothelioma, Neoplasm Metastasis, Carcinoma, Merkel Cell, Endometrial Neoplasms, Small Cell Lung Carcinoma

NCT05263492 2025-10-02

Study of Lenvatinib w/ Pembro in Black Participants w/Mismatch Repair-Prof Recurrent Endometrial Cancer

4 enrolled 8 charts

Recurrence, Endometrial Neoplasms

NCT06264921 2025-09-25

A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors

BreastGastrointestinalGynecologicThoracic

23 enrolled

Neoplasm Metastasis, Ovarian Neoplasms, Stomach Neoplasms, Uterine Diseases, Endometrial Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04278144 2025-09-15

A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors

BreastGastrointestinalGynecologicHead & NeckThoracic

175 enrolled

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT04458259 2025-08-28

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

DermatologicGastrointestinalGenitourinaryGynecologicThoracic

88 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Small Cell Lung Carcinoma

NCT06321068 2025-08-14

BAT1308 in Combination With Platinum-containing Chemotherapy is Used for the First-line Treatment of Advanced or Recurrent dMMR Endometrial Cancer

Phase 2/3 Terminated

5 enrolled

Endometrial Neoplasms

NCT04159155 2025-08-12

CAN-STAMP

Phase 2/3 Terminated

11 enrolled

GastrointestinalGynecologicThoracic

Endometrial Neoplasms, Cystadenocarcinoma, Serous

NCT05124743 2025-07-30

HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With Solid Tumors

Terminated

19 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06299163 2025-07-23

NM32-2668 in Adult Patients With Selected Advanced Solid Tumors

BreastDermatologicGenitourinaryGynecologicOther solid neoplasmSarcomaThoracic

11 enrolled

Adenocarcinoma of Lung, Mesothelioma, Malignant, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Leiomyosarcoma, Liposarcoma, Melanoma, Ovarian Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05714553 2025-07-18

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

19 enrolled

Squamous Cell Carcinoma of Head and Neck, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Esophageal Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT04577963 2025-07-14

A Study of Fruquintinib in Combination With Tislelizumab in Advanced Solid Tumors

BreastGastrointestinalGynecologic

52 enrolled 23 charts

Breast Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05274451 2025-07-01

A Study to Investigate LYL797 in Adults With Solid Tumors

BreastGynecologicThoracic

57 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Fallopian Tube Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Recurrence, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05891197 2025-07-01

START

Terminated

10 enrolled

BreastGynecologicThoracic

NCT04527900 2025-06-19

The UPPROACH (Upfront Intensity Modulated Proton Beam Therapy) Approach

2 enrolled

Endometrial Neoplasms

NCT03277482 2025-05-31

Durvalumab, Tremelimumab + Radiotherapy in Gynecologic Cancer

16 enrolled

Uterine Cervical Neoplasms, Ovarian Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms

NCT04152018 2025-05-28

Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors.

GastrointestinalGenitourinaryGynecologicHead & Neck

85 enrolled

Squamous Cell Carcinoma of Head and Neck, Bile Duct Neoplasms, Carcinoma, Renal Cell, Esophageal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Endometrial Neoplasms

NCT05396794 2025-05-15

SCC-BAREDU

Terminated

26 enrolled

GynecologicOther

Obesity, Endometrial Neoplasms

NCT05067972 2025-05-06

C4431001

30 enrolled 20 charts

BreastGynecologic

Breast Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT04514692 2025-04-23

Bone Marrow Sparing Image-Guided Radiation Therapy (RT) Incorporating Novel Use of GCSF and FDG-PET Imaging

7 enrolled 9 charts

Uterine Cervical Neoplasms, Endometrial Neoplasms

NCT04209465 2025-04-17

MasterKey-01

BreastGastrointestinalGenitourinaryGynecologicThoracic

91 enrolled 26 charts

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT05523440 2025-03-28

Bevacizumab and/or Niraparib in Patients With Recurrent Endometrial and/or Ovarian Cancer With ARID1A Mutation

7 enrolled

Ovarian Neoplasms, Endometrial Neoplasms

NCT04750941 2025-03-04

Study of Copanlisib and Ketogenic Diet

Phase EARLY_PHASE1 Terminated

1 enrolled 9 charts

GynecologicLymphoid

Lymphoma, Follicular, Endometrial Neoplasms

NCT04906382 2025-02-13

Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial Cancer

2 enrolled

GastrointestinalGynecologic

Turcot syndrome, Colorectal Neoplasms, Hereditary Nonpolyposis, Endometrial Neoplasms

NCT05229900 2025-02-10

A Study of SGN-ALPV in Advanced Solid Tumors

GastrointestinalGenitourinaryGynecologicThoracic

43 enrolled

Ovarian Germ Cell Cancer, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Endometrial Neoplasms

NCT04665921 2025-02-07

A Study of SGN-STNV in Advanced Solid Tumors

GastrointestinalGynecologicThoracic

111 enrolled

Adenocarcinoma, Mucinous, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Ovarian Neoplasms, Pseudomyxoma Peritonei, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT03601897 2024-12-27

A Phase 1b/2 Study of Rebastinib (DCC-2036) in Combination With Paclitaxel in Patients With Advanced or Metastatic Solid Tumors

177 enrolled 25 charts

BreastGynecologicSarcoma

Breast Neoplasms, Carcinosarcoma, Neoplasm Metastasis, Ovarian Neoplasms, Endometrial Neoplasms

NCT03099499 2024-12-24

Single Agent ONC201 in Recurrent or Metastatic Endometrial Cancer

19 enrolled

Endometrial Neoplasms

NCT05500508 2024-12-24

Oral AMXT 1501 Dicaprate in Combination With IV DFMO

BreastCNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckOther solid neoplasmThoracic

15 enrolled

Thyroid Cancer, Papillary, Diffuse Intrinsic Pontine Glioma, Mesothelioma, Malignant, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioma, Head and Neck Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT03514121 2024-11-22

FPA150-001

Phase EARLY_PHASE1 Terminated

95 enrolled 36 charts

BreastGynecologic

Breast Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT05001282 2024-08-07

A Study to Evaluate ELU001 in Patients With Solid Tumors That Overexpress Folate Receptor Alpha (FRα)

79 enrolled