Clinical Trials

Carcinoma, Intraductal, Noninfiltrating, Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Hereditary Breast and Ovarian Cancer Syndrome

NCT05721326 2026-01-13

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

1,330 enrolled

Breast Neoplasms, Neoplastic Syndromes, Hereditary, Ovarian Neoplasms, Genetic Predisposition to Disease, Genetic Diseases, Inborn, Hereditary Breast and Ovarian Cancer Syndrome

NCT02760849 2026-01-07

Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

374 enrolled

Phase NA Not yet recruiting

Hereditary Breast and Ovarian Cancer Syndrome

NCT07236359 2025-11-19

Reborn-i

108 enrolled

Breast Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT06892275 2025-09-30

The FYI on MRI: A Multilevel Decision Support Intervention for Screening Breast MRI

Phase NA Recruiting

80 enrolled

Hereditary Breast and Ovarian Cancer Syndrome

NCT03426878 2025-09-11

CHARM

967 enrolled 13 charts

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Hereditary Breast and Ovarian Cancer Syndrome

NCT05130606 2025-08-28

CONTIGO - A Narrative Intervention to Enhance Genetic Counseling and Testing

Phase NA Recruiting

332 enrolled

Breast Neoplasms, Ovarian Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT02653105 2025-08-15

Women at Risk of Breast Cancer and OLFM4

150 enrolled

Phase NA Enrolling by invitation

Hereditary Breast and Ovarian Cancer Syndrome

NCT06914726 2025-08-05

PC-CDS

2,488 enrolled

Colorectal Neoplasms, Hereditary Nonpolyposis, Neoplastic Syndromes, Hereditary, Ovarian Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT06534424 2025-06-27

Clinical Impact of Enhanced Risk Assessments in Women With a BRCA1/2 Mutation, CARE Study

152 enrolled

Hereditary Breast and Ovarian Cancer Syndrome

NCT03246841 2024-12-12

TUMOSPEC

7,274 enrolled

Breast Neoplasms, Ovarian Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT04197856 2024-07-09

DIRECT

490 enrolled

Breast Cancer, Familial, Colorectal Neoplasms, Hereditary Nonpolyposis, Hereditary Breast and Ovarian Cancer Syndrome

NCT00673335 2024-07-01

LIBER

Phase 3 Completed

170 enrolled

Breast Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT02087592 2024-04-16

LIBRE

69 enrolled

Hereditary Breast and Ovarian Cancer Syndrome

NCT04508764 2024-04-16

Implementation of the Families Accelerating Cascade Testing Toolkit (FACTT) for Hereditary Breast and Ovarian Cancer and Lynch Syndrome

Phase NA Terminated

96 enrolled

Colorectal Neoplasms, Hereditary Nonpolyposis, Hereditary Breast and Ovarian Cancer Syndrome

NCT02516540 2024-04-11

LIBRE-2

Phase NA Unknown

600 enrolled

Hereditary Breast and Ovarian Cancer Syndrome

NCT05306002 2024-03-05

Nutritional Intervention and DNA Damage of Patients With HBOC

34 enrolled

BreastGenitourinaryGynecologic

Hereditary Breast and Ovarian Cancer Syndrome

NCT02203513 2022-09-10

A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer

Phase 2 Terminated

111 enrolled 15 charts

Breast Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT04544501 2022-05-02

Enhance the Use of Genetic Counseling and Testing in Latinas

61 enrolled

Hereditary Breast and Ovarian Cancer Syndrome

NCT03511690 2022-04-25

Testing an Intelligent Tutoring System to Enhance Genetic Risk Assessment

95 enrolled

Hereditary Breast and Ovarian Cancer Syndrome

NCT02705924 2021-11-30

Impact of a Psychoeducational Intervention on Expectations and Coping in Young Women Exposed to a High HBOC Risk

Phase NA Terminated

32 enrolled

Hereditary Breast and Ovarian Cancer Syndrome

NCT02956681 2021-10-04

Statewide Communication to Reach Diverse Low Income Women

88 enrolled

Hereditary Breast and Ovarian Cancer Syndrome

NCT00305695 2020-03-24

Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries

160 enrolled 10 charts

Osteoporosis, Ovarian Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT03075540 2019-12-12

Enhancing At-risk Latina Women's Use of Genetic Counseling for Hereditary Breast and Ovarian Cancer

88 enrolled

Hereditary Breast and Ovarian Cancer Syndrome

NCT02451735 2019-11-08

Genetic Counseling for Breast Cancer Survivors (GC for BC)

157 enrolled

Breast Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome, Triple Negative Breast Neoplasms

NCT03162276 2018-09-07

Trial of Inquiry Based Stress Reduction (IBSR) Program for BRCA1/2 Mutation Carriers

Phase 3 Unknown

118 enrolled

BreastGastrointestinalGenitourinaryGynecologic

Hereditary Breast and Ovarian Cancer Syndrome

NCT00892736 2018-06-29

Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy

Phase 1 Completed

98 enrolled

Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome, Triple Negative Breast Neoplasms

NCT03294343 2017-12-26

Risk-Reducing Surgeries for Hereditary Ovarian Cancer

Phase NA Unknown

600 enrolled

Colorectal Neoplasms, Hereditary Nonpolyposis, Hereditary Breast and Ovarian Cancer Syndrome

NCT00685256 2017-05-17

Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age Children

Phase 3 Completed

245 enrolled

Breast Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT02562170 2015-09-29

Protexa® Versus TiLoopBra® in Immediate Breast Reconstruction- A Pilot Study

Phase 4 Completed

50 enrolled

Breast Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT00535119 2015-05-22

Veliparib, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Cancer

Phase 1 Completed

107 enrolled

Hereditary Breast and Ovarian Cancer Syndrome

NCT01367639 2013-11-25

Trial of Inquiry Based Stress Reduction (IBSR) Program for BRCA1/2 Mutation Carriers

67 enrolled

Hereditary Breast and Ovarian Cancer Syndrome

NCT00321633 2013-08-26

Carboplatin or Docetaxel in Treating Women With Metastatic Genetic Breast Cancer

148 enrolled

Breast Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT01333748 2012-07-13

EXSAL

530 enrolled

Breast Neoplasms, Ovarian Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT00609505 2012-02-22

Telemedicine vs. Face-to-Face Cancer Genetic Counseling

130 enrolled

Breast Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Ovarian Neoplasms, Hereditary Breast and Ovarian Cancer Syndrome

NCT00253539 2011-04-13

Arzoxifene or Tamoxifen in Preventing Breast Cancer in Premenopausal Women at High Risk for Breast Cancer

3 enrolled