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Phase

Phase EARLY_PHASE1 1Phase 1 1

Status

Terminated 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Thoracic 57Other solid neoplasm 57Sarcoma 2Gynecologic 2Gastrointestinal 2Breast 2Lymphoid 1Head & Neck 1Genitourinary 1Endocrine 1CNS 1

Conditions

Uterine Cervical Neoplasms 182Ovarian Neoplasms 92Carcinoma, Ovarian Epithelial 46Fallopian Tube Neoplasms 35Endometrial Neoplasms 29Peritoneal Neoplasms 23Stomach Neoplasms 18Colorectal Neoplasms 13Carcinoma, Non-Small-Cell Lung 13Neoplasms 11Vulvar Neoplasms 9Recurrence 9Lung Neoplasms 8Squamous Cell Carcinoma of Head and Neck 7Pancreatic Neoplasms 7Locally Advanced Cervical Cancer 7Brenner Tumor 7Uterine Neoplasms 6Testicular Neoplasms 6Parkinson Disease 4, Autosomal Dominant Lewy Body 6Neoplasm Metastasis 6Carcinoma 6Urinary Bladder Neoplasms 5Sarcoma 5Colonic Neoplasms 5Breast Neoplasms 5Vaginal Neoplasms 4Triple Negative Breast Neoplasms 4Teratoma 4Small Cell Lung Carcinoma 4

Interventions

pembrolizumab 2fludarabine 2SS1(dsFv)PE38 2Platinum 2Hyperthermic Intraperitoneal Chemotherapy 2Cyclophosphamide 2Cisplatin 21,2-diaminocyclohexaneplatinum II citrate 2sodium thiosulfate 1enzalutamide 1entinostat 1X-Rays 1Surveys and Questionnaires 1Surgical Procedures, Operative 1Specimen Handling 1Referral and Consultation 1Polymerase Chain Reaction 1Paclitaxel 1Nivolumab 1Microarray Analysis 1Megestrol Acetate 1Magnetic Resonance Spectroscopy 1Levoleucovorin 1Leucovorin 1Ipilimumab 1Interleukin-2 1In Situ Hybridization, Fluorescence 1Immunoenzyme Techniques 1Gene Expression Profiling 1Gemcitabine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Mesothelioma, Malignant × Cisplatin × Gynecologic × Clear all
NCT04491942 2026-04-13

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

National Cancer Institute (NCI)

Phase 1 Active not recruiting
74 enrolled
BreastGenitourinaryGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Penile Neoplasms, Triple Negative Breast Neoplasms

NCT04213794 2025-02-20

TOASTIT

Mayo Clinic

Phase EARLY_PHASE1 Terminated
2 enrolled
GastrointestinalGynecologicOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Colonic Neoplasms, Fallopian Tube Neoplasms, Liposarcoma, Ovarian Neoplasms, Pelvic Neoplasms, Rectal Neoplasms, Rhabdomyosarcoma, Sarcoma, Stomach Neoplasms, Desmoplastic Small Round Cell Tumor

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