Announcements Trials
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Phase

Phase EARLY_PHASE1 1Phase 1 1

Status

Terminated 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Thoracic 7Other solid neoplasm 7Gynecologic 2Genitourinary 2Sarcoma 1Gastrointestinal 1Breast 1

Conditions

Uterine Cervical Neoplasms 19Ovarian Neoplasms 12Fallopian Tube Neoplasms 9Stomach Neoplasms 4Vulvar Neoplasms 3Vaginal Neoplasms 2Peritoneal Neoplasms 2Mesothelioma, Malignant 2Carcinoma, Ovarian Epithelial 2Brenner Tumor 2Vomiting 1Uterine Neoplasms 1Triple Negative Breast Neoplasms 1Sertoli-Leydig Cell Tumor 1Sarcoma 1Rhabdomyosarcoma 1Recurrent Uterine Corpus Carcinoma 1Rectal Neoplasms 1Prostatic Neoplasms 1Penile Neoplasms 1Pelvic Neoplasms 1Ovarian gynandroblastoma 1Neoplasm Metastasis 1Nausea 1Lung Neoplasms 1Locally Advanced Cervical Squamous Cell Carcinoma, Not Otherwise Specified 1Locally Advanced Cervical Carcinoma 1Locally Advanced Cervical Adenocarcinoma 1Liposarcoma 1HIV Infections 1

Interventions

pembrolizumab 2fludarabine 2SS1(dsFv)PE38 2Platinum 2Hyperthermic Intraperitoneal Chemotherapy 2Cyclophosphamide 2Cisplatin 21,2-diaminocyclohexaneplatinum II citrate 2sodium thiosulfate 1enzalutamide 1entinostat 1X-Rays 1Surveys and Questionnaires 1Surgical Procedures, Operative 1Specimen Handling 1Referral and Consultation 1Polymerase Chain Reaction 1Paclitaxel 1Nivolumab 1Microarray Analysis 1Megestrol Acetate 1Magnetic Resonance Spectroscopy 1Levoleucovorin 1Leucovorin 1Ipilimumab 1Interleukin-2 1In Situ Hybridization, Fluorescence 1Immunoenzyme Techniques 1Gene Expression Profiling 1Gemcitabine 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Mesothelioma, Malignant × Platinum × Gynecologic × Clear all
NCT04491942 2026-04-13

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

National Cancer Institute (NCI)

Phase 1 Active not recruiting
74 enrolled
BreastGenitourinaryGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Penile Neoplasms, Triple Negative Breast Neoplasms

NCT04213794 2025-02-20

TOASTIT

Mayo Clinic

Phase EARLY_PHASE1 Terminated
2 enrolled
GastrointestinalGynecologicOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Colonic Neoplasms, Fallopian Tube Neoplasms, Liposarcoma, Ovarian Neoplasms, Pelvic Neoplasms, Rectal Neoplasms, Rhabdomyosarcoma, Sarcoma, Stomach Neoplasms, Desmoplastic Small Round Cell Tumor

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