Clinical Trials

GastrointestinalGenitourinaryGynecologic

89 enrolled

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Neoplasm Metastasis, Pancreatic Neoplasms, Endometrial Neoplasms

NCT07458347 2026-04-15

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

GastrointestinalGynecologicThoracic

145 enrolled

Biliary Tract Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07189702 2026-04-08

BEND-MBEC

Phase NA Not yet recruiting

60 enrolled

Phase 2 Active not recruiting

Neoplasm Metastasis, Endometrial Neoplasms

NCT03428802 2026-04-03

Pembrolizumab in Treating Participants With Metastatic, Recurrent or Locally Advanced Cancer and Genomic Instability

21 enrolled 9 charts

BreastGynecologic

Breast Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms

NCT05036681 2026-03-27

A Phase II Study of Futibatinib and Pembrolizumab in Metastatic Microsatellite Stable Endometrial Carcinoma

Phase 2 Terminated

9 enrolled 10 charts

Neoplasm Metastasis, Endometrial Neoplasms

NCT05143970 2026-03-20

CHANCES

BreastGastrointestinalGynecologicThoracic

27 enrolled

Breast Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Endometrial Neoplasms

NCT05269381 2026-03-12

PNeoVCA

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

132 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Carcinosarcoma, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Carcinoma, Merkel Cell, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT06349642 2026-03-12

ELEPHAS-04

DermatologicGastrointestinalGenitourinaryGynecologicSarcomaThoracic

324 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinosarcoma, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Neoplasm Metastasis, Skin Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT05686226 2026-02-27

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

GastrointestinalGenitourinaryGynecologicHead & Neck

20 enrolled

Anus Neoplasms, Uterine Cervical Neoplasms, Neoplasm Metastasis, Oropharyngeal Neoplasms, Penile Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms

NCT07282834 2026-02-27

Charlie-2

200 enrolled

Phase 2 Not yet recruiting

Neoplasm Metastasis, Neoplasms, Peritoneal Neoplasms

NCT07424664 2026-02-20

A Single-arm, Multicenter Clinical Study of Becotatug Vedotin Combined With Zimberelimab in the Treatment of Recurrent and Metastatic Cervical Cancer, Vulvar Cancer and Vaginal Cancer

30 enrolled

Uterine Cervical Neoplasms, Neoplasm Metastasis, Recurrence, Vaginal Neoplasms, Vulvar Neoplasms

NCT07410494 2026-02-18

SELECT-CAR-NK

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidOther hematologic neoplasmPlasma cellThoracic

85 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Carcinoma, Hepatocellular, Liver Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Leukemia, Myeloid, Acute

NCT07410676 2026-02-18

EBNK-ST-001

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicOther hematologic neoplasmSarcomaThoracic

83 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Bronchogenic, Disease, Esophageal Neoplasms, Glioblastoma, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms

NCT07030283 2026-02-02

Intraperitoneal Paclitaxel With NALIRIFOX for Pancreatic Ductal Adenocarcinoma With Peritoneal Carcinomatosis

10 enrolled

Neoplasm Metastasis, Peritoneal Neoplasms

NCT05542407 2026-01-29

ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer

Phase 2 Not yet recruiting

58 enrolled

GynecologicOtherSarcoma

Carcinosarcoma, Disease, Neoplasm Metastasis, Obesity, Endometrial Neoplasms

NCT07363330 2026-01-26

A Phase II Study of Utidelone With Toripalimab in Advanced Cervical Cancer

32 enrolled

Phase 1 Active not recruiting

Uterine Cervical Neoplasms, Neoplasm Metastasis, Recurrence

NCT04673448 2026-01-09

Niraparib and TSR-042 for the Treatment of BRCA-Mutated Unresectable or Metastatic Breast, Pancreas, Ovary, Fallopian Tube, or Primary Peritoneal Cancer

18 enrolled

BreastGastrointestinalGynecologic

Breast Neoplasms, Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms

NCT06626256 2025-12-24

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Phase 1 Withdrawn

DermatologicGastrointestinalGenitourinaryGynecologic

Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT04329494 2025-12-10

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

GastrointestinalGynecologic

49 enrolled

Appendiceal Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Uterine Neoplasms, Colorectal Neoplasms

NCT06107868 2025-12-08

GyneRep

Phase 1 Active not recruiting

6 enrolled

Phase 3 Active not recruiting

Neoplasm Metastasis, Ovarian Neoplasms, Uterine Neoplasms

NCT05201547 2025-12-04

DOMENICA

260 enrolled

BreastGastrointestinalGenitourinaryGynecologicThoracic

Neoplasm Metastasis, Endometrial Neoplasms

NCT05472532 2025-11-20

INOVOLINE

Phase NA Completed

101 enrolled

Breast Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Stomach Neoplasms

NCT05475171 2025-11-19

Triage of Advanced Cervical Cancer Through Immunotherapy Induction (TRACTION)

40 enrolled

Uterine Cervical Neoplasms, Neoplasm Metastasis

NCT05296564 2025-10-02

Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers

BreastCNSDermatologicGynecologicSarcomaThoracic

3 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Sarcoma, Synovial, Triple Negative Breast Neoplasms

NCT05021237 2025-08-28

Personalized Ultra-fractionated Stereotactic Adaptive Radiotherapy for Metastatic Cervical Cancer

Phase 2 Active not recruiting

12 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Uterine Cervical Neoplasms, Neoplasm Metastasis

NCT05714553 2025-07-18

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

Phase 1/2 Terminated

19 enrolled

Squamous Cell Carcinoma of Head and Neck, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Esophageal Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT07040657 2025-06-27

Comparison of Two-Position and Four-Position Cervical Injection Techniques for Sentinel Lymph Node Mapping in Endometrial Cancer Using Methylene Blue

Phase NA Recruiting

100 enrolled

BreastDermatologicGenitourinaryGynecologicThoracic

Neoplasm Metastasis, Endometrial Neoplasms

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Phase 1 Terminated

221 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT05518253 2025-05-31

A Clinical Study of CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors

BreastGastrointestinalGynecologicSarcoma

30 enrolled

GenitourinaryGynecologic

Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms

NCT02632448 2025-05-02

A Study of LY2880070 in Participants With Advanced or Metastatic Cancer

Phase 1/2 Completed

229 enrolled

Breast Neoplasms, Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Sarcoma, Colorectal Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors, Triple Negative Breast Neoplasms

NCT06599463 2025-03-20

LARENA

Completed

351 enrolled

Phase EARLY_PHASE1 Not yet recruiting

Neoplasm Metastasis, Neoplasms, Endometrial Neoplasms

NCT06825455 2025-02-13

Allogeneic B7H3 CAR-γδT Cell Therapy for Advanced Solid Tumors

18 enrolled

Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms

NCT02732860 2025-01-30

REFLECT

BreastGastrointestinalGynecologic

120 enrolled

Breast Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Colorectal Neoplasms

NCT06686043 2024-11-13

HPV-VIM

85 enrolled

Uterine Cervical Neoplasms, Neoplasm Metastasis, Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms, Papillomavirus Infections

NCT01600040 2024-10-29

Proton Beam Teletherapy for Post-Hysterectomy Cancers of the Uterus and Cervix

Phase NA Completed

22 enrolled 6 charts

Uterine Cervical Neoplasms, Neoplasm Metastasis, Uterine Neoplasms

NCT06532539 2024-08-01

Cadonilimab With Chemoradiation for Recurrent and Oligometastatic Endometrial Carcinoma

30 enrolled

GastrointestinalGenitourinaryGynecologic

Neoplasm Metastasis, Neoplasm Recurrence, Local, Neoplasms, Endometrial Neoplasms

NCT03439085 2024-07-09

DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers

Phase 2 Terminated

41 enrolled 13 charts

Anal Canal Carcinoma, Anus Neoplasms, Uterine Cervical Neoplasms, Neoplasm Metastasis, Neoplasms, Penile Neoplasms, Recurrence, Vaginal Neoplasms, Vulvar Neoplasms

NCT05610501 2024-07-03

Ultrasound-guided Tru-Cut Biopsy in Pelvic Masses.

200 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmPlasma cellSarcomaThoracic

Uterine Cervical Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pelvic Neoplasms, Uterine Neoplasms, Endometrial Neoplasms

NCT04604158 2024-05-21

Evaluating the Effect of a Mobile Audio Companion (Elly) to Reduce Anxiety in Cancer Patients

Phase NA Completed

38 enrolled

Anxiety Disorders, Urinary Bladder Neoplasms, Breast Neoplasms, Glioblastoma, Head and Neck Neoplasms, Kidney Neoplasms, Leukemia, Lung Neoplasms, Lymphoma, Melanoma, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Social Isolation, Uterine Neoplasms, Colorectal Neoplasms

NCT06413992 2024-05-14

Camrelizumab Plus Fluzoparib for TP-53 Mutated Endometrial Cancer

117 enrolled

Phase 1 Not yet recruiting

Neoplasm Metastasis, Recurrence, Endometrial Neoplasms

NCT06383507 2024-04-25

A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors

18 enrolled

GenitourinaryGynecologicHead & Neck

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms

NCT02333604 2024-04-15

CER