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Phase

Phase 1/2 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 1Gynecologic 1Gastrointestinal 1

Conditions

Uterine Cervical Neoplasms 2Endometrial Neoplasms 2Vulvar Neoplasms 1Vulvar Diseases 1Uterine Cervical Dysplasia 1Rectal Neoplasms 1Papillomavirus Infections 1Ovarian Neoplasms 1Oropharyngeal Neoplasms 1Lung Neoplasms 1Head and Neck Neoplasms 1Esophageal Neoplasms 1Cystadenocarcinoma, Serous 1Carcinoma in Situ 1Breast Neoplasms 1Anus Neoplasms 1

Interventions

fludarabine 4aldesleukin 4Cyclophosphamide 4pembrolizumab 2fludarabine phosphate 2Polymerase Chain Reaction 2Gene Expression Profiling 2Counseling 2Bupropion 2Biopsy 2Adoptive Transfer 2entinostat 1bintrafusp alfa protein, human 1Zinc Oxide 1Vorinostat 1Varenicline 1Tomography, X-Ray Computed 1Tobacco Use Cessation Devices 1Taxes 1Surveys and Questionnaires 1Ritonavir 1Radiotherapy 1Psychiatric Rehabilitation 1Nicotine Replacement Therapy 1Nicotine 1NHS-IL12 immunocytokine 1Magnetic Resonance Imaging 1Liquid Biopsy 1Interleukin-2 1Indinavir 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Oropharyngeal Neoplasms × Diphenhydramine × Gynecologic × Clear all
NCT04432597 2026-05-18

HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

National Institutes of Health Clinical Center (CC)

Phase 1/2 Active not recruiting
39 enrolled
GastrointestinalGynecologicHead & Neck

Anus Neoplasms, Uterine Cervical Neoplasms, Oropharyngeal Neoplasms, Rectal Neoplasms

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