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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 8Thoracic 1Lymphoid 1Gynecologic 1Genitourinary 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Ovarian Neoplasms 45Uterine Cervical Neoplasms 21Fallopian Tube Neoplasms 20Carcinoma, Ovarian Epithelial 15Neoplasms 8Endometrial Neoplasms 8Lung Neoplasms 7Breast Neoplasms 5Stomach Neoplasms 4Recurrence 4Pancreatic Neoplasms 4Neoplasm Metastasis 4Melanoma 4Head and Neck Neoplasms 4Gestational Trophoblastic Disease 4Vulvar Neoplasms 3Peritoneal Neoplasms 3Kidney Neoplasms 3Esophageal Neoplasms 3Colorectal Neoplasms 3Uterine Neoplasms 2Sarcoma 2Lymphoma, Non-Hodgkin 2Liver Neoplasms 2Laryngeal Neoplasms 2Hydatidiform Mole 2Gynecologic Cancer 2Glioblastoma 2Colonic Neoplasms 2Cholangiocarcinoma 2

Interventions

fludarabine 4aldesleukin 4Cyclophosphamide 4pembrolizumab 2fludarabine phosphate 2Polymerase Chain Reaction 2Gene Expression Profiling 2Counseling 2Bupropion 2Biopsy 2Adoptive Transfer 2entinostat 1bintrafusp alfa protein, human 1Zinc Oxide 1Vorinostat 1Varenicline 1Tomography, X-Ray Computed 1Tobacco Use Cessation Devices 1Taxes 1Surveys and Questionnaires 1Ritonavir 1Radiotherapy 1Psychiatric Rehabilitation 1Nicotine Replacement Therapy 1Nicotine 1NHS-IL12 immunocytokine 1Magnetic Resonance Imaging 1Liquid Biopsy 1Interleukin-2 1Indinavir 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Oropharyngeal Neoplasms × Drug Therapy × Gynecologic × Clear all
NCT03329950 2024-03-28

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

Celldex Therapeutics

Phase 1 Completed
132 enrolled
BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Mouth Neoplasms, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Cholangiocarcinoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Hyper-IgM Immunodeficiency Syndrome

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